Biology Test 1 Flashcards

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1
Q

What is the bottom-up approach to producing synthetic life?

A

Bottom-up approaches seek to assemble a group of non-living components that collectively will exhibit the characteristics of life.

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2
Q

What does David Deamer feel is the ‘final’ problem that keeps synthetic life (Life 2.0) from being a laboratory reality?

A

The inability of synthetic systems to make more catalysts.

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3
Q

Deamer, the optimist, says “ Is there any hope? The answer is yes, a faint glimmer of hope.” Which of the following is NOT a reason behind his use of the word hope?

A

It is not yet clear how to apply von Neumann’s theory to synthetic life.

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4
Q

Deamer proposes the use of ribozymes, which are engineered RNA molecules that don’t naturally exist. Ribozymes can be engineered to perform a limited range of catalytic functions. What other attribute would ribozymes have to have in order to provide a solution to Deamer’s dilemma?

A

They would have to be able to copy themselves.

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5
Q

When Adam Reid says that he thinks the Venter group did the equivalent in the computer world “to ditching Windows and installing Linux in its place,” what is he saying in criticism of their claim of constructing a synthetic organism?

A

Venter’s group wrote new (synthetic) software to drive existing (natural) hardware (the recipient bacterial cell).

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6
Q

According to Adam Reid, all criticism of the Venter group’s claims aside, they did make some major contributions. What were these contributions or advances? At least two of these answers are correct and you should choose all of the correct answers.

A

New methods which advance the ability to synthesize much longer DNA molecules than ever before.

Techniques which allow a genetic program to be successfully transplanted into a recipient organism.

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7
Q

Venter’s group mainly copied the known code of Mycoplasma mycoides into a chemically synthesized DNA molecule. Several errors (mutations) inadvertantly occurred during the production of the synthetic DNA and initially were fatal in that they prevented the successful rebooting of the recipient cell with the synthetic DNA. What is the primary significance of this for synthetic biology?

A

It shows that it will be difficult to engineer new genes without producing fatal mutations.

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8
Q

Dr. Jim Collins says that “Biology is messy and …often gets in the way of clever engineering”. What is the profound truth in this sarcastic statement?

A

Biology shows us we don’t understand because our designs don’t work.

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9
Q

Why is DNA viewed as the operating system of the cell since the concept of an operating system (such as the Mac OS or Windows) is a computer concept?

A

Operating systems control hardware in both cases, but they are distinct from the hardware they control.

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10
Q

The label ‘top down’ has been applied to a management style where all decisions of significance are made by a few executives. We applied the label ‘top down’ to the approach of Venter’s group to synthetic biology because:

A

It starts with the goal of synthetic biology, a functional living organism, to try to understand how to produce synthetic life.

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11
Q

Which of these is NOT an acceptable analogy to what Venter’s group accomplished?

A

A baboon heart transplanted into a human.

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12
Q

What motivated the first attempt at biological classification?

A

A conviction that God created the world in an organized and purposeful way.

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13
Q

Which of these is NOT true of the concept of biological discontinuity?

A

The gradual accumulation of mutations in genes causes organisms to produce distinct types.

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14
Q

Although the biological world is fundamentally discontinuous, some discontinuities are more significant than others.

The most fundamental discontinuity (for which there are no intermediate forms) is that which separates organisms based on:

A

whether they have a nucleus.

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15
Q

Who invented the process of classification (taxonomy) and what were the largest categories in their classification?

A

Linnaeus; Plants, Animals

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16
Q

Which of these is NOT a good reason why classification systems undergo frequent revision?

A

The growth of scientific understanding of how organisms function.

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17
Q

What is involved in the traditional concept of a universal common ancestor?

A

The view that all living organisms evolved from a single organism that was the first living thing.

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18
Q

Which of these is the best characterization of the status of biological classification?

A

There is no consensus on classification because of scientitist’s inability to harmonize all of the discordant data.

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19
Q

What is the significance of the fact that traditionally biologists have represented life with a tree, but that now they have taken to using the shrub as a more accurate characterization?

A

Highly significant because a shrub doesn’t have a single trunk

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20
Q

What is the meaning in this diagram of the places where lines intersect on this diagram (what do the nodes signify)?

A

They signify organisms predicted by evolution, but not yet discovered.

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21
Q

Apes and humans both contain genes which are recognizable as very similar and yet have a few differences in their codes. Which of these should NOT characterize the response of Bible-Believers?

A

Expect that the few differences in the codes of the genes will turn out to be functionally very significant.

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22
Q

Why is a biological classification system needed?

A

It provides a standard of comparison when I need to determine the identity of an organism I have collected.

The sheer number of different kinds of living organisms demands a logical approach to organizing them.

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23
Q

Many organisms already have common names, so why do we bother to assign scientific names to them in addition to their common name? For example why bother with Canis familiaris since we already have the name, dog? Choose all that apply.

A

Scientists don’t like the common names that are used

Common names don’t have an obvious rationale behind them
.
Common names may differ from one part of the world to another.

Scientific names are informative and tell us something significant about the organism.

Scientific names mesh with the logic of the classification system.

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24
Q

What language is at the root of scientific names like Canis familiaris?

A

Latin

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25
Q

Why are scientific names italicized (or underlined) when they are found in print? Think of Canis familiaris.

A

Because they are Latin terms.

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26
Q

Is there a logic behind scientific names?

A

Yes, they are logical and are based on the name of the person who discovered the organism.

Yes, they are logical and are based on some characteristic of the organism.

27
Q

Which of these did Venter’s group NOT claim to have accomplished?

A

Created synthetic life.

28
Q

According to the article, what is the bedrock of traditional classification?

A

The study of morphology (form).

29
Q

What is the difference between classification and identification?

A

Classification involves creating an organized system in which known organisms are purposely placed and when an organism is found, it can be identified based on the classification of other, similar, specimens.

30
Q

Which of these is NOT a disadvantage of traditional identification methods?

A

They require the existence of a well-thought-out classification sytem.

31
Q

Which of these is NOT the reason that a single gene in mitochondrial DNA was chosen as the basis for barcoding?

A

The CO1 gene of mitochondria is very similar in divergent types of organisms.

32
Q

In principle what is involved in determining that an organism just barcoded as described is, in fact, a brand-new previously unknown organism?

A

The barcode is outside the normal range of variation for barcodes of known organisms.

33
Q

Which of these is NOT true of rats?

A

Rats have been placed on the IUCN list as ‘modest concern.

34
Q

Based on your reading within the sources included in Case 3, which of these statements is factually true?

A

Fewer than 50 people worldwide have eaten golden rice.

35
Q

Golden rice was produced through the process of bioengineering. Which of these is a true statement in regard to this process as it was carried out in golden rice?

A

The Golden Rice project was a humanitarian initiative and will never make money.

36
Q

The Golden Rice Biosafety page says “Fewer than about 50 people have tasted Golden Rice so far.” Which of these is the correct reason based on the sources in Case 3?

A

The Golden Rice Board is trying to be extremely cautious so that the scientific data from testing will make the case that Golden Rice is safe.

37
Q

Greenpeace says that “GE Rice Threatens Biodiversity.” Which of these is/are sound reason(s) to be suspicious of this claim?

A

There are already over 20,000 varieties of rice which exist without threatening each other.

Hybrids of rice are difficult to produce in the wild.

The Greenpeace web article was big on assertion and remarkably short on scientific evidence.

38
Q

What is Noel Kingsbury’s position on the definition of ‘natural’ as applied to fruits and vegetables that were available decades ago before agriculture became a big business?

A

They were the result of thousands of years of selective breeding.

39
Q

According to the publisher’s statement, what does Kingsbury feel were the driving forces behind human efforts at producing hybrids (new varieties)?

A

To make the fruits and vegetables more attractive to buyers.

To make fruit and vegetable production more reliable

To increase plant productivity and thus the yield from each planting.

To make fruits and vegetables more nutritious.

40
Q

To what extent were the farmers who engaged in selective breeding and hybridization well-informed about what they were doing?

A

Although technically skilled, farmers and scientists until quite recently (20 years) had to adopt a try-it-and-see mentality because cause-effect in hybridization was not understood at the genetic level.

41
Q

What common misconceptions about genes does Dr. Collins attack in the following quote:

“Although the Human Genome Project has expanded the parts list for cells, there is no instruction manual for putting them together to produce a living cell. It is like trying to assemble an operational jumbo jet from its parts list — impossible.”

A

DNA is destiny. Cells and organisms are all just readouts of our DNA.

42
Q

According to your reading, which of thes is NOT a reason why it has been difficult to estimate the number of different kinds of microbes (microscopic organisms) in environments like the ocean?

A

Microbes are found in very diverse environments.

43
Q

Metagenomics (environmental genomics) is a revolutionary approach to estimating the number of microbes in environments primarily because it

A

Concentrates on recovering communities of genes rather whole microbes.

44
Q

The Sorcerer II expedition in the Sargasso Sea directly identified:

A

Over a million genes.

45
Q

Which of these is a good reason for studying Mycoplasma genitalium based on the abstract you just read?

A

This organism has the smallest number of genes of any known organism.

46
Q

What is the implication of being able to disrupt a gene in Mycoplasma genitalium and having the organism continue to function?

A

The gene codes for something which is not absolutely required for life

47
Q

What is the logical connection between disabling genes in a living organism and producing a synthetic life form? (This involves making an inference and would not be found in the abstract directly).

A

Determining what genes the cell can do without helps synthetic biologists know what functions a synthetic cell must include.

Determining what genes are absolutely vital helps us to better understand natural cells so that we more fully appreciate how genes are responsible for life functions from an engineering vantage point.

48
Q

Which of these is NOT compatible to the concept of a paradox? A statement or group of statements which:

A

Require deep understanding to reconcile

49
Q

What is these is NOT part of the essence of a chicken and egg paradox? These are in the form of “Which came first, the chicken or the egg?”

A

Differences in maturity

50
Q

All life that we know of is based on a combination of DNA, RNA, and protein. DNA is the repository of coded information, RNA is a temporary copy of the DNA code (a blueprint) used in the synthesis (in cooperation with proteins in machines called ribosomes) of proteins. Proteins perform most of the actions of the cell.The foundational relationship of DNA/RNA/Protein is called the Central Dogma of Molecular Biology.

There is a paradox here. Which of the following is the best statement of the paradox?

A

Protein machines are required in order for the blueprint in RNA to cause the production of more proteins.

51
Q

Which of these is an accurate statement about the place of prokaryotic organisms in the living world?

A

Prokaryotes outnumber eukaryotes and outweigh eukaryotes in nearly every environment on earth.

52
Q

Which of these is NOT an environment in which prokaryotes have been found to live (not just survive)?

A

At high temperatures such as those in the molten lava of an erupting volcano

53
Q

Which of these is NOT true of hydrothermal vent ecosystems?

A

Their primary energy source is sunlight.

54
Q

Prokaryotes living in deep-sea environments use a variety of chemical sources of energy. Mark ALL of the sources that they use.

A

Iron
Hydrogen sulfide
Methane
Hydrogen

55
Q

The biosphere is that portion of planet earth where life is found. In the 1950’s scientists believed that living organisms lived in only the upper few meters of the earth’s crust and perhaps the upper 100 meters or so of the ocean. Why was the region below this considered incapable of supporting life? Mark ALL correct answers (at least they would have been defended as correct in the 1950’s—they have all been disproven since then).

A

Lack of sunlight
High pressure
Too far away from the photosynthetic organisms that power the food chain.

56
Q

According to the abstract, how many species of beetles (Coleoptera) were found in Erwin’s study in Panama?

Use numerals only in your answer.

A

945

57
Q

How many kinds of trees did Erwin sample in this study?

A

1

58
Q

In this study, how many different trees were sampled by fogging?

Use numerals only in your answer.

A

19

59
Q

Based on the abstract you read, what was Terry Erwin’s intent in conducting this research study.

A

to determine the number and species richness of beetles (Coleoptera) in the forest canopy of Panama.

60
Q

What does the body make from Vitamin A that makes vision possible?

A

Retinal

61
Q

What is it that actually absorbs the light when it enters the eye?

A

Rhodopsin

62
Q

What is the defect in vision that Vitamin A deficiency causes in adults?

A

night blindness

63
Q

What is/are the most prevalent defect(s) Vitamin A deficiency causes in children? (Select all correct answers)

A

Total Blindness

Death

64
Q

The exact structure of Rhodopsin is known.

A

False