Biology paper 1 Flashcards
Cells -
Contains genetic information that controls the functions of the cell.
Nucleus
Cells -
Controls what enters and leaves the nucleus.
Cell membrane
Cells -
Where many cell activities and chemical reactions in the cell occur.
Cytoplasm
Cells -
Provides energy from aerobic respiration
Mitochondria
Cells -
Synthesis (makes) proteins
Ribosome
Cells -
Where photosynthesis occurs
Chloroplast
Cells -
Used to store water and other chemicals as cell sap
Permanent vacuole
Cells -
Strengthens and supports the cell. (Made of cellulose in plants).
Cell wall
Cells -
A loop of DNA, not enclosed within a nucleus.
DNA loop
Cells -
A small circle of DNA, may contain genes associated with antibiotic resistance.
Plasmid
Cells -
Acrosome contains enzymes to break into egg; tail to swim; many mitochondria to provide energy to swim.
Sperm cell
Cells -
Long to transmit electrical impulses over a distance.
Nerve cell
Cells -
Contain protein fibres that can contract when energy is available, making the cells shorter.
Muscle cell
Cells -
Waterproofed cell wall; cells are hollow to allow water to move through.
Xylem cell
Cells -
Some cells have lots of mitochondria for active transport; some cells have very little cytoplasm for sugars to move through easily.
Phloem cell
Cells -
Long extension to increase surface area for water and mineral uptake; thin cell wall.
Root hair cell
Cells -
Contains: cytoplasm, nucleus, ribosome, mitochondria and cell membrane.
Animal cell
Cells -
Contains: cytoplasm, nucleus, ribosome, mitochondria, cell membrane, chloroplast, vacuole and cell wall.
Plant cell
Microscopy -
The degree by which an object is enlarged
Magnification
Microscopy -
The ability of a microscope to distinguish detail.
Resolution
Microscopy -
Basic microscope with a maximum magnification of 1500x. Low resolution.
Light microscope
Microscopy -
Microscope with a much higher magnification and resolving power than a light microscope. This means that it can be used to study cells in much finer detail.
Electron microscope
Mitosis and the cell cycle
- Number of sub-cellular structures increase
- Number of chromosomes double
- One set of chromosomes is pulled to each end of the cell
- The nucleus divides
- Cytoplasm and cell membranes divide to form two identical cells
Stem cells -
Can divide into most types of cells
Used for therapeutic cloning
Embryonic stem cells
Stem cells -
Can divide into a limited number of cells
Adult stem cell
Stem cells -
Found in plants
Can differentiate (divide) into any type of plant cell
Meristem
Pros of using stem cells
Treatment of diseases such as diabetes, dementia and paralysis
Cons of using stem cells
Ethical and religious objections
Can transfer viruses held within cells
Transport across membranes -
Diffusion definition
Spreading out of the particles resulting in a net movement from an area of higher concentration to an area of lower concentration
Transport across membranes -
Diffusion use
Oxygen and carbon dioxide in gas exchange (leaves and alveoli)
Urea from cells into the blood plasma for excretion in the kidney
Transport across membranes -
Osmosis definition
The diffusion of water from a dilute solution to a concentrated solution through a partially permeable membrane.
Transport across membranes -
Osmosis use
Movement of water into and out of cells
Transport across membranes -
Active transport definition
The movement of substances from a more dilute solution to a more concentrated solution. Requires energy from respiration.
Transport across membranes -
Active transport use
Absorption of mineral ions (low concentration) from soil into plant roots. Absorption of sugar molecules from lower concentration in the gut into the blood which has a higher sugar concentration.
Factors affecting diffusion -
Difference in concentrations explanation
The greater the difference in concentrations, the faster the rate of diffusion.
Factors affecting diffusion -
Temperature explanation
Particles move more quickly at higher temperatures, so rate of diffusion increases.
Factors affecting diffusion -
Surface area of membrane explanation
The greater the surface area the quicker the rate of diffusion.
Adaptation of exchange surfaces
- Large surface area
- Thin membrane (provides short diffusion path)
- Ventilation (in animals for gas exchange - maintains a concentration gradient)
- Efficient blood supply (in animals - maintains a concentration gradient
Organisation -
Tissue
A group of cells with a similar structure and function
muscle, tissue
Organisation -
Organ
A group of tissues performing a specific function
heart, leaf
Organisation -
Organ system
A group of organs that perform a specific function (digestive system)
Enzymes key terms -
Enzyme
A biological catalyst that can speed up the rate of reaction without being used itself. Made of a large protein molecule.
Enzymes key terms -
Substrate
The chemical that fits into the active site of an enzyme
Enzymes key terms -
Lock and key model
Only one type of substance can fit into the active site of an enzyme, like a key fits into a lock.
Enzymes key terms -
Denatured
When the active site of an enzyme changes shape and the substrate can no longer fit in. Can be caused by pH or temperature.
Testing for biological molecules -
Starch chemical test
Add orange/brown iodine solution
Testing for biological molecules -
Starch positive result
Colour turns blue/black
Testing for biological molecules -
Sugar chemical test
Add blue Benedict’s solution. Place in a boiling water bath for 5 minutes
Testing for biological molecules -
Sugar positive result
Colour turns green / yellow / orange / brick red
Testing for biological molecules -
Protein chemical test
Add blue Biuret solution
Testing for biological molecules -
Protein positive result
Colour turns lilac/purple
Testing for biological molecules -
Lipid chemical test
Add ethanol and decant into water
Testing for biological molecules -
Lipid positive result
Cloudy white emulsion
Human digestive enzymes -
Amylase
Function - breaks starch into sugars
Sites of production - salivary glands, pancreas, small intestine
Sites of action - mouth, small intestine
Human digestive enzymes -
Protease
Function - breaks proteins into amino acids
Sites of production - stomach, pancreas, small intestine
Sites of action - stomach, small intestine
Human digestive enzymes -
Lipase
Function - breaks lipids (fats) into fatty acids and glycerol
Sites of production - pancreas, small intestine
Sites of action - small intestine
Other chemicals -
Hydrochloric acid
Acid with pH produced by the stomach. Unravels proteins.
Other chemicals -
Bile
Emmulsifies fats (turns them into droplets to give a greater surface area). It is alkaline so neutralises acids from the stomach. Produces in liver, stored in gall bladder and is released into the small intestine.
Structures in the heart -
Pacemaker
Group of cells in the right atrium that controls resting heart rate.
Structures in the heart -
Right ventricle
Pumps deoxygenated blood to the lungs for gas exchange.
Structures in the heart -
Left ventricle
Pumps oxygenated blood to the body. Thick, muscular wall.
Structures in the heart -
Valve
Stops blood flowing the wrong way / leaking.
Structures in the lungs -
Alveoli
Small sacs where gas exchange occurs. Surrounded by capillaries. Oxygen moves from the alveoli into the capillaries, carbon dioxide moves from the capillaries into the alveoli.
Structures in the lungs -
Trachea and Bronchi
Tubes through which gases move. Lined with cartalige so they don’t collapse.
Heart disease -
Coronary heart disease
Build up of fatty material in coronary arteries. Can lead to a blood clot and a heart attack.
Heart disease treatment -
Stent
What - wire mesh that opens up a blocked artery
Advantage - keeps artery open, low risk of surgery
Disadvantage - fatty materials can rebuild
Heart disease treatment -
Statin
What - drug that reduces cholesterol
Advantage - reduces fat being deposited in arteries
Disadvantage - side effects (liver damage)
Heart disease treatment -
Heart transplant
What - replacement heart from a donor
Advantage - long-term
Disadvantage - major surgery, could be rejected
Heart disease treatment -
Artificial heart
What - man-made heart used while waiting for transplant
Advantage - not rejected, keeps patient alive
Disadvantage - short life time, battery has to be transported, limited activity
Heart disease treatment -
Mechanical heart valve
What - mechanical replacement of faulty heart valve
Advantage - can last a life-time
Disadvantage - can damage red blood cells
Heart disease treatment -
Biological heart valve
What - biological replacement of faulty heart valve
Advantage - don’t damage red blood cells
Disadvantage - valve hardens and may need replacing
Blood vessels -
Artery
Purpose - takes blood away from the heart
Adaptation - thick wall to withstand high pressure
Blood vessels -
Vein
Purpose - takes blood back the the heart
Adaptation - thin wall. Valves to prevent backflow of blood.
Blood vessels -
Capillary
Purpose - exchange of substances between blood and cells
Adaptation - wall is one cell thick to allow quick diffusion of substances
Components of the blood -
Plasma
Liquid part of the blood. Transport blood cells as well as carbon dioxide, proteins, glucose, hormones and urea.
Components of the blood -
Red blood cells
Carries oxygen. Packed with haemoglobin, a protein that blinds to oxygen. No nucleus to create extra space for haemoglobin. Biconcave shape to give a large surface area.
Components of the blood -
White blood cells
Destroys pathogens. Some can produce antibodies.
Components of the blood -
Platelets
Cell fragments that help to clot wounds.
Movement within plants -
Transpiration
The loss of water vapour from the leaves by evaporation from cells and then out through the stomata.
Movement within plants -
Transpiration stream
The movement of water from the roots, up the steam to the leaves.
Movement within plants -
Translocation
The movement of dissolved sugars around the plant
Factors affecting transpiration -
Temperature
Increasing temperature increases the transpiration rate as water evaporates quickly.
Factors affecting transpiration -
Humidity
Increasing humidity decreases the rate of transpiration as water evaporates slowly.
Factors of transpiration -
Wind speed
Increasing wind speed increases the transpiration rate as water evaporates quickly.
Factors of transpiration -
Light
Increasing light increases the rate of transpiration as the stomata opens.
Cell adaptation for movement within plants -
Root hair cell
Extension gives a large surface area to absorb water and minerals.
Cells adaptation for movement within plants -
Xylem
Vessels are strengthened by lignin to withstand pressure. Cell walls are waterproof.
Cell adaptation for movement within plants -
Phloem
End of cells contain pores to allow dissolved sugars to move between cells.
Cell adaptation for movement within plants -
Guard cells & Stomata guard cells
Can open the stomata to allow gas exchange or close to prevent water loss.
Leaf structure and plant tissues -
Epidermis
Covers the surfaces of the leaf; lets light penetrate.
Leaf structure and plant tissues -
Xylem
Carries water and minerals from the roots around the plant.
Leaf structure and plant tissues -
Phloem
Carries dissolved sugars made through photosynthesis around the plant.
Leaf structure and plant tissues -
Palisade mesophyll
Where most photosynthesis takes place. Cells contain many chloroplasts. Absorbs light.
Leaf structure and plant tissues -
Spongy mesophyll
Some photosynthesis. Has air spaces for diffusion of carbon dioxide and oxygen.
Leaf structure and plant tissues -
Guard cells
Cells that open and close stomata.
Leaf structure and plant tissues -
Stoma
Opening that allows carbon dioxide and oxygen to diffuse in and out of the leaf.
Pathogens and disease -
Measles
Pathogen - virus
Spread - droplets from sneezes and coughs
Effect - can be fatal
Prevention - vaccination of children
Pathogens and disease -
HIV
Pathogen - virus
Spread - sexual contact, needle exchange
Effect - damages some white blood cells
Prevention - antiretroviral drugs when infected
Pathogens and disease -
Tobacco mosaic virus
Pathogen - virus
Spread - direct contact
Effect - mottling leaves, reduces photosynthesis
Pathogens and disease -
Salmonella
Pathogen - bacteria
Spread - infected food
Effect - fever, abdominal cramps, diarrhoea, vomiting
Prevention - vaccinations of poultry (chickens)
Pathogens and disease -
Gonorrhoea
Pathogen - bacteria
Spread - sexual contact
Effect - discharge from penis/vagina, pain when urinating
Prevention - controlled by anitbiotics, spread prevented by condoms
Pathogens and disease -
Rose black sport
Pathogen - fungus
Spread - spores carried by water or wind
Effect - leaves turn yellow, fall early. Photosynthesis reduced
Prevention - treated by fungicides or destroying affected leaves
Pathogens and disease -
Malaria
Pathogen - protist
Spread - by a vector - mosquito
Effect - fever, can be fatal
Prevention - preventing mosquito’s from breeding, using mosquito nets
Non-specific defences -
Tranchea and bronchi
Produces mucus to trap pathogens. Contains cilia to move mucus for swallowing.
Non-specific defences -
Nose
Contains hairs and mucus to trap pathogens.
Non-specific defences -
Stomach
Contains hrydrochloric acid to destroy pathogens.
Non-specific defences -
Skin
Physical barrier to pathogens.
Key terms -
Pathogen
A microorganism that causes disease.
Key terms -
Bacteria
A type of pathogen that produces toxins that damage tissues.
Key terms -
Viruses
A type of pathogen that lives and replicates with cells and causes cell damage. It is difficult to kill viruses without damaging cells.
Key terms -
Antibodies
Some white blood cells produce antibodies. These bind to pathogens and destroy them or stick them together.
Key terms -
Antitoxins
Some white blood cells produce antitoxins. Antitoxins neutralise toxins.
Key terms -
Antibiotics
Antibiotics kill bacteria. Specific antibiotics should be used for specific bacteria. Some bacteria are resistant to antibiotics. Do not kill viruses.
Key terms -
Painkillers
Painkillers relive symptoms but don’t kill pathogens.
Key terms -
Phagocytosis
Some white blood cells engulf pathogens.
Drugs -
Aspirin
Originates from the willow tree.
Drugs -
Digitalis
A heart drug. Originates from foxglove plants.
Drugs -
Penicillin
Discovered by Alexander Fleming from the penicillium fungus.
Drugs -
New drugs
Most new drugs are synthesised by chemists in the pharmaceutical industry. The starting point may be a chemical extracted from a plant.
Clinical trials -
Preclinical - cells, animals
Tests for toxicity and efficacy before testing humans.
Clinical trials -
Healthy volunteers
Very low doses to test for toxicity.
Clinical trials -
Patients
Larger groups. Test for toxicity, efficacy and dose. Placebos may be used in double-blind trial.
Clinical trial key terms -
Placebo
A drug with no active ingredients, designed to mimic a real drug. Used to test i the effects of a drug on a patient are just psychological.
Clinical trial key terms -
Double-blind trial
The volunteers do not know which groups they are in, and neither do the researchers, until the end of the trial.
Clinical trial key terms -
Toxicity
How harmful the drug is. May have dangerous side effects.
Clinical trial key terms -
Efficacy
How effective the drug is.
Clinical trail key terms -
Dose
The amount of the drug given to the patient.
Photosynthesis equation
Carbon dioxide + water = glucose + oxygen
Key terms -
Chloroplast
The plant organelle where photosynthesis takes place.
Key terms -
Chlorophyll
The green pigment that absorbs energy from light.
Key terms -
Endothermic
Photosynthesis takes energy in (in the form of light). It is an endothermic reaction.
Key terms -
Diffusion
The spreading out of particles by random motion from where they are in high concentration. Occurs is gasses and liquids.
Uses of glucose
- Used in respiration to provide energy
- Converted into starch for storage
- Converted into fats and oils for storage
- Produce cellulose to strengthen cell wall
- Produce amino acids to make proteins (also needs nitrate ions from the soil)
Limiting factor
The factor that stops the rate of photosynthesis from increasing; could be light intensity, carbon dioxide, temperature or amount of chlorophyll.
Respiration -
Energy
Energy in organisms is needed for chemical reactions to build larger molecules, movement and keeping warm.
Respiration -
Aerobic respiration
Aerobic respiration provides energy. It requires oxygen. It is an exothermic reaction (produces heat). In mitochondria.
Aerobic respiration word equation
glucose + oxygen = carbon dioxide + water
Respiration - Anaerobic respiration (muscles)
No oxygen needed. Provides less energy than aerobic respiration as glucose not fully oxidised. Occurs during intensive exercise. In cytoplasm.
Respiration -
Lactic acid
Produced in anaerobic respiration in muscles. Build up of lactic acid causes fatigue. Lactic acid must be taken to the liver by the blood so that it can be oxidised back to glucose.
Respiration -
Oxygen debt
The amount of extra oxygen the body needs after exercise to react with the lactic acid and remove it.
Respiration - Anaerobic respiration (plant & yeast cells)
No oxygen needed. In yeast cells it is called fermentation - economically important for manufacture of bread and alcoholic drinks. In cytoplasm.
Respiration - Anaerobic respiration (plant & yeast cells) word equation
glucose = ethanol + carbon dioxide
Response to exercise -
Increase in breathing rate
Increases rate at which oxygen is taken in the lungs.
Response to exercise -
Increase in heart rate
Oxygenated blood is pumped around the body at a faster rate. Carbon dioxide is removed at a faster rate.
Response to exercise -
Increase in breath volume
A greater volume of oxygen is taken into each breath.
Metabolism
The sum of all the reactions in a cell or body. Some of these reactions require the energy released from respiration.
Metabolism reactions
- Conversion of glucose to starch, cellulose or glycogen
- Formation of lipids from glycerol and fatty acids
- Use of glucose and nitrates to make amino acids (plants only)
- Respiration
- Breakdown of proteins to urea