Biology - Mitosis/Meiosis/Cancer Flashcards

Defining Mitosis Meiosis and Cancer

1
Q

Is a big cell always better?

A
  • If a cells size is doubled then it would require 8x more nutrients and have 8x more waste to excrete
  • Surface area increases by 4x
  • Plasma membrane would not have enough surface area to allow oxygen, nutrients, and wastes to diffuse
  • Cells would either die from their own waste or starve to death
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2
Q

Cell size:

A
  • Limited in size
  • Female egg is the largest cell in the human body (can be seen without a microscope)
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3
Q

Structure of eukaryote chromosomes

A

During most of cells life cycle, the chromosomes exist as CHROMATIN (strands of DNA wrapped around protein)

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4
Q

Chromosomes

A

When cell enters mitosis, chromatin coils up into the form of chromosomes

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5
Q

Chromosomes structure

A
  • Consists of DNA wrapped
    around proteins (Histones)
  • DNA & histone molecules form bead like structures called NUCLEOSOMES
  • Nucleosomes fold DNA and become tightly packed to form chromosomes during mitosis
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6
Q

Two Copies

A
  • Due to DNA replication in the S phase, each chromosomes has an identical copy
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7
Q

The Cell Cycle

A
  • Cells go through to two general periods
  • Interphase is the growth period (growing)
  • Mitosis is the period of division (÷ of nucleus)
  • Most of the cells life is spent carrying out the activities of interphase.
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8
Q

What is cytokinesis ?

A

When the chromosome membrane splits

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9
Q

What are the roles of cell division ÷

A
  • Un unicellular organisms
    + Method of Reproduction
  • Multi cellular organisms
    + Growth
    + Maintenance
    + Replacement
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10
Q

What are spindles and what stage of the cell cycle are they found?

A
  • Found in the Metaphase stage
  • Football shaped structure consisting of thin fibers made of micro-tubes
  • Separates sister chromatids
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11
Q

What is a chromatid

A
  • Esch sister chromatic is attached to its own spindle fiber
  • Ensures that each new cell will get an identical and complete set of chromosomes
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12
Q

What is Cytokinesis and what cells is it found in?

A
  • Found in animal cells
  • Toward the end of telophase the plasma membrane pinches in along the equator to creat two separate cell identical to the original
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13
Q

What happens to plant cells?

A
  • PLasma membrane doesn’t pinch in. Instead, a cell plate is formed and is place across the cells equator. (Picture a line down the center of the cell)
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14
Q

What is contacts inhibition?>

A
  • Cell to cell communication
  • Cells communicate w/ each other by producing band secreting chemical signals
  • When changes occur in the genetic control of these chemicals - cancer can result.
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15
Q

What is the structure and function of DNA?

A
  • DNA is made up of nucleotides
  • Each. Nucleotide contains:
    + Deoxyribose (sugar)
    + a phosphate group
    + a nitrogen base
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16
Q

What are the 4 bases of nucleotides?

A
  • Adenine (A)
  • Thymine (T)
  • Cytosine (C)
  • Guanine (G)
    (A & T go together and C & G go together)
17
Q

What 2 bases are purines?

A

Adenine and guanine

18
Q

What 2 bases are pyrimidines?

A

Cytosine and thymine

19
Q

What are Chargaff’s rules?

A
  • the % of guanine and cytosine in a cell are =
  • the % of adenine and thymine are =
  • The amount of purines = the amount of pyrimidines
20
Q

Structure of DNA

A
  • 2 chains of nucleotides in DNA are joined by hydrogen bonds between bases
  • Covalent bonds join the sugar and phosphate sides together
21
Q

How does Mitosis reproduce?

A
  • Asexual (Clones)
  • single parent (only 1 cell needed)
  • Passes all genes from 1 parent
  • Offspring is genetically identical
22
Q

How does Meiosis reproduce?

A
  • Sexual (Variation)
  • 2 parents
  • Each parents passes down half of their genes
  • Offspring have unique genetic combination
23
Q

How many rounds or meiosis are there?

A

2 rounds of cell ÷:

24
Q

What happens in Meiosis 1?

A
  • Prophase 1
  • Métaphase 1
  • Anaphase 1
  • Telophase 1 & cytokinesis
25
Q

What happens in Meiosis 2?

A
  • Prophase 2
  • Metaphase 2
  • Anaphase 2
  • Telophase 2 and cytokinesis
26
Q

What happens in Prophase 1?

A
  • Crossing over occurs (introduces genetic diversity)
  • Forms a tetrad
  • Homologous chromosomes pair up & form tetrads
  • Can exchange portions of their chromatids
  • Results to produce new genetic combinations
27
Q

What is the result of Meiosis 2?

A
  • Produces 4 genetically different cells
    Males: 4 sperm cells
    Females: 1 egg & 3 polar bodies (Polar bodies don’t participate in reproduction)
28
Q

What is genetic recombination?

A
  • Peas have 7 pairs of chromosomes
    + pease can form up to 128 different kinds of sperm
  • Humans have 23 pairs of chromosomes
  • They can form up to 8 million different kinds of sperm or eggs.
29
Q

What is Interphase?

A
  • Nucleus is still visible
  • DNA is in loose strand of chromatin
  • G1: Cell grows
  • S: DNA replication
  • G2: Preparation for Mitosis
30
Q

What happens in Prophase?

A
  • Chromatin coils into chromosomes and becomes visible
  • Centrioles separate and move to poles
  • Nucleolus disappears
  • Nuclear envelope breaks down
31
Q

What happens in Metaphase?

A

Chromosomes line up along the middle (equator) of the cell

32
Q

What happens in Anaphase?

A
  • Centromeres separate
  • Sister chromatids separate into chromosomes
  • Chromosomes move to opposite poles
33
Q

What happens in Telophase?

A
  • Chromosomes reach poles and begin to uncoil
  • Nuclear envelope re-forms
  • Spindle breaks apart
  • Nucleus becomes visible
34
Q

What happens in Cytokinesis?

A
  • Division of the cytoplasm
  • Plants develop a cell plate