BIOLOGY LECTURE FINALS Flashcards
GREGOR MENDEL AND ELEMENTARY GENETICS
The term genetics was derived from the greek word ____ meaning ____ .
This term was first coined by ____ in 1906.
_____ is the branch of biology that deals with the principles of heredity and variation in all living things.
Gen
To become/ to grow into something
William bateson
Heredity
GREGOR MENDEL AND ELEMENTARY GENETICS
____ is our genetic heritage, passing from the parents to their offspring. These traits can be physical, a disease or behavioral and _____ is the difference in the genetic make up or physical appearance of a different organisms
Heredity
Variation
GREGOR MENDEL AND ELEMENTARY GENETICS
BRANCHES OF BIOLOGY
1. ____ Field that studies the structure and function of genes at a molecular level.
2. ____ Study the processes by which organisms grow and develop
3. ____ concerned with the study of the structure and function of the cell, especially the chromosomes
4. ____ the study of how genetic variation leads to evolutionary change
5. ____ study of the fundamental relationship between genes, protein, and metabolism. This involves the study of the cause of many specific heritable disease
Molecular genetics
Developmental genetics
Cytogenetics
Evolutionary genetics
Biochemical genetics
GREGOR MENDEL AND ELEMENTARY GENETICS
BRANCHES OF GENETICS
6. ___ the field of study that examines the role of genetics in animal (including human) behavior
7. ___ the study of allele frequency distribution and change under the influence of the four main evolutionary processes: natural selection, genetic drift, mutation and gene flow
8._____ the study of continuously measured traits (such as height or weight) and their mechanisms
Behavioral genetics
Population genetics
Quantitative genetics
APPLICATION OF GENETICS (5)
1. This includes selective breeding, producing high yielding crops, advancements in meat production through breeding that supplied the protein needs, and the use of selected microbial strains that improved the fermentation of foods and food products.
2. Genetic diseases and abnormalities have been identified and appropriate preventive measures are prescribed. Knowing the nature of these defects made it easier to take the preventive steps, including gene therapy.
3. Knowledge of the inheritance of certain desirable or undesirable characteristics will help individuals, prospective parents, and families to understand their genetic history and adapt to the most effective way of treatment, if necessary.
4. Genetics helped solve problems of disputed parentage in settling child support, estate claims or even baby mix-up in hospitals. DNA profiles or fingerprints of suspects have been found to be an accurate tool in identifying criminals.
5. This involves joining of DNA segments from different biological sources producing genetically modified organism (GMO) or transgenic plants, animals, or microorganisms. Therapeutic proteins, hormones and vaccines are also produced using this technology.
Plant, animal and microbial improvement
Medicine
Genetic counseling
Legal application
Recombinant DNA Technology
THEORY OF _____ by ____
This theory suggests that ____ small particles in the body were formed everywhere in the man’s body and such gemmule reflected the characteristics of the body part from where it was formed.
Pangenesis
Charles darwin
Gemmules
_____ proposed his theory of ____ based on the pangenesis theory. Body modifications acquired by use or disuse could be transmitted to the offspring because the gemmules formed reflected such modifications. He stated that CHANGE IS WHAT ORGANISMS WANT OR NEED
Jean Baptiste de Lamarck
Theory of Inheritance of acquired characteristics
____ disproved the theory of pangenesis with his theory of ____.
This theory proposed that ____ or sex cells perpetuated themselves in reproduction generation after generation. While ____ or body cells were reproduced by germplasm to protect and reproduce itself.
August weisman
Germplasm theory
Germplasm
Somatoplasm
He discovered that hereditary characteristic were determined by elementary factors that are transmitted between generations. He believe that ___ is inherited from generation to generation that each descendant has a physical copy of this material
Gregor mendel
Gene
MENDELIAN OBSERVATION
• Garden peas are ____, they are true-breeding plants. They always produce offspring that look like the parent
• Garden peas mature within ___
• Large quantities of garden peas could be ___
Mendel applied _____ he classified the hybrid ___ and determined their perspective frequencies
Self-pollinating
One season
Cultivated simultaneously
Quantitative approach
Progenies
Mendel observed seven characteristics from his garden peas, each with two contrasting traits.
• For the seeds, he observed the ___ (either round or wrinkled)
• ____ (yellow or green)
• Flower color ( white or violet)
• ____ (full or constricted) and color ___
• ___ (axial pods with flowers along terminal pods with flower at top) and ___ (long or short)
• Mendel confirmed that he was using ___ for white or violet flower color (How mendel perform his experiment)
Form
Color
Pod form
Yellow or green
Stem place
Stem size
True-breeding plants
MENDELIAN OBSERVATION
•___ are those that are inherited unchanged in a hybridization while ___ disappear in the offspring of hybridization but reappear in the offspring of the hybrids
Dominant traits
Recessive
CHROMOSOMES THEORY OF INHERITANCE
In 1903 ____ and ____ independently suggested the pair factors (in Mendel’s observation) is paralleled by the separation of homologous chromosomes during meiosis
• The individual genes are found at specific locations on chromosomes, and the behavior of chromosomes during meiosis can explain why genes are inherited, these observation proposed the ____
• This theory was confirmed when ___ discovered the sex chromosomes on his study about fruit flies
Walter sutton and theodor boveri
Chromosome theory of inheritance
Thomas hunt morgan
CHROMOSOMES
The term chromosomes comes from the greek words ___ and ___ which stands for color and body. Chromosomes are thread like structure located inside the nucleus of the cell. The ___ provides support for the structure of chromosomes coiling it and keeping it highly condensed
Chroma
Soma
Protein histone
CHROMOSOMES
Chromosomes are also ___ females have two _ Chromosomes (XX) while males have one _ and one _ (__)
Chromosomes has different parts :
• ___ the constricted region of the chromosomes. It help keep chromosomes properly aligned during cell division and the attachment site for the sister chromatids
• ___ are located at the ends of the chromosomes. Protect the ends of the chromosomes and sustain chromosome stability
• ___ region on either side of the centromere.
• The short arm ___
• The long arm ___
Sex determinants
X (XX)
X & Y (XY)
Centromere
Telomeres
Chromosomes arms
P arm
Q arm
TYPES OF CHROMOSOMES
• Chromosomes can be ____ when centromere occupies the terminal position, so that the chromosomes has just one arm.
• ____ when the centromere occupies a sub-terminal position (one arm is very long and other is very short)
• ____ Chromosomes are when centromere is positioned slightly awar from the mid-point so that the two arms are unequal.
• ____ is when centromere lies in the middle of chromosomes so that the two arms are almost equal
Telocentric
Acrocentric
Sub-metacentric
Metacentric
DNA STRUCTURE
The DNA are made up of ____
• In 1944 ___, ____ and ___ concluded that the DNA is the genetic material. But DNA was first identified in the late 1860s by swiss chemist ____
• DNA is composed of repeating nucleotides, which are made up of a ___ (ribose or deoxyribose) , a ___ (purine (G,A) And pyrimidines (C,T) and ___
Bases ( Cytosine, Guanine, Adenine, Thymine)
Deoxyribonucleic acid
Oswald avery, colin macleod and maclyn mcCarty
Friedrich miescher
Pentose sugar
Nitrogenous base
Phosphoric acid
CENTRAL DOGMA
First used by ___
Summarize the event from DNA to RNA to protein production. It explains the flow of genetic information in making functional proteins.
• This describes the step-by-step process of the duplication of the DNA (__), how DNA is transcribed into RNA (__) and how RNA is translated into proteins (__)
Francis crick
Central dogma
Replication
Transcription
Translation
CENTRAL DOGMA (REPLICATION)
• During DNA replication, each of the two strands that make up the double helix serves as a template from which new strands are copied. The new strand will be complementary to the parental or “old” strand. This is known as ___ replication.
• There are specific nucleotide sequence called ____ at which replication process begins. When the helicase unwinds and opens the DNA, a Y-Shaped structure called ____ is formed
Semiconservative replication
Origins of replication
Replication fork
DNA (TRANSCRIPTION)
• The region of unwinding is called a ___
• Transcription proceeds from one of the two DNA strands, called the ____ RNA polymerase moves along the template strand, separates the two strands while complementing DNA template nucleotide with RNA nucleotides.
- ___ are complexed with ribosomal proteins to form ribosomes, which are protein synthesizing organelles of the cell.
- ___ provides the template that contains the nucleotide code for the amino acid sequence of a protein.
- ___ transfer amino acids from the cytoplasm to the ribosomes
Transcription bubbles
Template strand
rRNA
mRNA
tRNA
DNA (TRANSLATION)
The process by which the mature mRNA is used as a template for synthesizing protein. Carried out in ribosomes. Each amino acid is defined by a three nucleotide sequence called a ___
• The relationship between a nucleotide codon and it’s corresponding amino acid is called the ___
• Three of the 64 codons terminate protein synthesis and release the polypeptide from the translation and machinery. They are UAA, UAG and UGA they are called ___
Codon
Genetic code
Stop codons
GENES AND GENE INTERACTIONS
Mendel concluded that individuals had two discrete copies of the characteristics that are passed individually to offspring. He called these as ____ which we call now genes
• A ___ is the unit of heredity occupying a particular location on the chromosomes and passed on to offspring.
• ___ are gene variants that exist at the same relative locations on homologous chromosomes
• The observable traits expressed by an organism are reffered to as its ___ (it is referred to the appearance of an organism) (height, eye color, etc.)
• organisms underlying genetic makeup is called its ___
Factors
Genes
Alleles
Phenotype
Genotype
GENES AND GENETIC INTERACTIONS.
____ is a hereditary factor express itself when present
____ Is a hereditary factor that is hidden and Expressed only when two recessive alleles are combined
• Mendel used in his experiment were each ____ for the trait he was studying. This means that an organism has two identical alleles, one on each of their homologous chromosomes.
• When p plants with contrasting traits were cross fertilized, all of the offspring were ___ for the contrasting traits meaning their genotype had different alleles for the gene being examined (Bb)
Dominant allele
Recessive
Homozygous
Heterozygous
LAW OF DOMINANCE
____ this states that heterozygote, one trait will conceal the presence of another trait for the same characteristics. Rather than both alleles contributing to a phenotype, the dominant allele will be expressed exclusively.
Law of dominance
MONOHYBRID CROSS
The fertilization between true breeding parents that differ by only the characteristics being studied. It is called ____
• a ___ is a device invented by ___ used for determining probabilities (measures of likelihood)
• ____ can be determined from a punnet square. And if the pattern of inheritance (dominant or recessive) is know, ___ can also be determined
Monohybrid cross
Punnet square
Reginald Punnet l
Genotypic ratios
Phenotypic ratio
LAW OF SEGREGATION
Mendel proposed the ___ this law states that paired unit factors (genes) must segregate equally into gametes such that offspring have an equal likelihood of inheriting either factor.
• In ___ the dominant expressing organisms is crossed with an organism that is homozygous recessive for the same characteristics
Law of segregation
Test score
LAW OF INDEPENDENT ASSORTMENT
___ states that genes do not influence each other regarding the sorting of alleles into gametes, and every possible combination of alleles for every gene is equally likely to occur.
It can be illustrated by the ____ a cross between two true breeding parents that express different traits for two characteristics
Law of independent assortment
Dihybrid cross
ANIMAL STRUCTURE AND FUNCTION
The word animal came from the Latin word ____ which means having breath. Animals are diverse group of organisms that make
up the ____
• ___ animals are composed of many cells that are fused together
• ___ animals obtain their energy by consuming the bodies of other organisms (Animals must convert these macromolecules into the simple molecules required for maintaining cellular function. This conversion is a multistep
process involving ____ and ___
• ____ animal reproduction is necessary for the survival of species
Animalis
Kingdom Animalia.
Heterotrophic
Digestion and absorption
Sexual reproduction
COMMON CHARACTERISTICS OF ANIMALS
___ The process in which an organism develops from a single-celled zygote to a multicellular organism is complex
and well-regulated.
• ____ undergoes rapid cell division to form ____ in the process termed as ____
•The blastula arranges
themselves in two layers: the ____ and the outer layer called the ____
• During ____ the embryonic stem cells express specific sets of genes which will determine their ultimate cell type
Development
Zygote
Blastula
Cleavage
Inner mass cells
Trophoblast
Differentiation
COMMON CHARACTERISTICS OF ANIMALS
___ Most animals are able to respond rapidly to external stimuli as a result of the activity of their nerve cells and
muscle cells.
•____ is the ability of an organism to move of its own accord by expending energy and it can be in the form
of walking, slithering, swimming, or flying to propel themselves through world.
• ____ is the biological property of an organism describing its lack of means of selflocomotion.
• Homeostasis- This “constancy of the internal milieu” was first recognized in the 19th century. Later on, the term homeostasis
was formed to describe the constancy of the body’s internal environment.
• These equilibrium conditions are maintained by mechanisms collectively called as ___
Movement
Motility
Sessility
Feedback systems
COMMON CHARACTERISTIC OF ANIMALS
• ___ When a change occurs in an animal’s environment, an adjustment must be made. The receptor senses the change in the environment,
then send signals to the control center which in turn generates a response. Homeostasis is maintained by this
• ____ maintains the direction of the stimulus, possibly accelerating it. One example here is the uterine contraction
during childbirth.
• ____ is the process of maintaining salt and water balance across membranes within the body. There is a constant
input of water and electrolytes (ions) into the system.
Negative feedback
Positive feedback (loop)
Osmoregulation
MAIN ANIMAL DIVISION
•____ animals have
no pattern or symmetry; example is a sponge.
•____ is when any plane cut along the
longitudinal axis through the organism produces
equal halves, but not a definite left or right side.
This is mostly found in aquatic animals.
• ____ is when an animal can be divided into roughly mirror-image halves only
along one particular plane through the central axis.
Asymmetrical
Radial symmetry
Bilateral symmetry
MAIN ANIMAL DIVISION
The evolution of bilateral symmetry is accompanied by ____ the concentration of sensory organs and brain in a defined head
region. Cephalization produces an ____(head) end, where sensory cells, sensory organs, cluster of nerve cells, and organs for
ingesting food are concentrated.
• The other end of a cephalized animal is designated ___
and may feature a tail.
• We also have the ___ side that contains the cranial and spinal
cord and
• the ____ side that contains the thoracic activity – one that surrounds the lungs
and heart
Cephalization
Anterior
Posterior
Dorsal
Ventral
MAIN ANIMAL DIVISION
____
The blastula
folds upon itself to form the three layers of cells. Each of these layers is called a germ
layer and each germ layer differentiates into different organ systems.
• The ___ gives rise to the nervous system and the epidermis.
• The ___ gives rise to the muscle cells and connective tissues in the
body.
• The ___ gives rise to columnar cells found in the
digestive system and many internal organs
Germ layers
Ectoderm
Mesoderm
Endoderm
MAIN ANIMAL DIVISION
___ The members of many bilateral animal have a fluid-filled
cavity between the digestive tube and the outer body wall.
• The most widespread type of body cavity is a ____ , a fluidfilled cavity that is completely lined with a thin layer of tissue
that develops from mesoderm.
Animals that have coelom are called coelomates. These are
the annelids, arthropods, mollusks, echinoderms, and
chordates.
• Other animals have a body cavity that is not
completely surrounded by a mesoderm-derived tissue. They
are called as ____ and they include the roundworms.
• While animals that do not have body cavity at
all are known as ____.
Body cavities
Coelom
Pseudocoelomates
Acoelomates
TYPES OF ANIMAL TISSUE
____
Epithelial cells are the body’s
gatekeepers, protecting and
regulating the movement of
substances in and out of the body
• The types of epithelial tissues are
classified by the shape of the cells
present, to which they can either be ___, ____ and ____
the number of layers of cells – either ____, ____ or ___.
Epithelial tissue
Cuboidal, columnar, squamous
Simple, stratified or psudostratified
TYPES OF ANIMAL TISSUE
_____ serve mainly to support and bind other tissues. Connective tissues can be place into three main categories:
1. _____ – also called the areolar
connective tissue; this combines with the epithelial tissues to form the membranes. They contain a diffuse
network of protein fibers, loosely woven through a clear extracellular fluid. It surrounds, cushions and supports most organs of the body.
2. ______ – contains collagen fibers,
which are densely packed in an orderly parallel arrangement – a design that contributes to the flexibility and tremendous strength of tendons and ligaments. Tendons connect bones to muscles, while ligaments connect bones to bones.
3. ________ – this includes the
cartilage, bone, fat, and blood.
•____ covers the ends
of bones at joints, provides the supporting framework for
the respiratory passages, support the ears and the nose,
and forms shock-absorbing pads between the vertebrae.
•_____ or ____ has large amount of two types of matrix material –
organic and inorganic matrix.
• _____ collectively known as ____
tissue are modified for long-term energy storage. They serve as
insulations to help maintain body temperature, and function in
cushioning against damage to body organs.
• ____ is considered a
connective tissue because it has a matrix
Connective tissue
Loose connective tissue
Fibrous connective tissue
Specialized connective tissue
Cartilage
Bone or osseous tissue
Fat cells / adipose tissue
Blood
TYPES OF ANIMAL TISSUE
____
You owe your ability to sense and respond to the world to nerve tissue,
which makes up the brain, the spinal cord, and the nerves that travel
from them to all parts of the body.
• ____ are specialized to generate electric signals and to conduct
these signals to other neurons, muscles, or glands. Glial cells surround,
support, electrically insulate, and protect neurons
Nervous tissue
Neurons
TYPES OF ANIMAL TISSUE
_____
The long, thin cells of muscle tissue contract (shorten) when stimulated, then relax passively. There are three types of muscle tissues
in an animal body: smooth, skeletal, and cardiac. They differ by the
presence or absence of striations or bands, the number and
location of nuclei, whether they are voluntary or involuntary, and
their location within the body.
1. ____ is generally under voluntary, or
conscious control. Its main function is to move the
skeleton, as occurs when you walk or turn the pages of a
book.
2. ____ is located only in the heart. It is
spontaneously active and involuntary.
3. ____ lacks the orderly arrangement of thick
and thin filaments. It is embedded in the walls of
digestive tract, the uterus, the bladder, and large blood
vessels. It produces slow, sustained contractions that are
mostly involuntary.
Skeletal muscle
Cardiac muscle
Smooth muscle
ORGAN SYSTEM ____
• MAJOR STRUCTURES
Mouth, esophagus, stomach, small and large
intestines, glands producing digestive secretions
• PHYSIOLOGICAL ROLE
Supplies the body with nutrients that provide energy and materials
for growth and maintenance
Digestive
ORGAN SYSTEM
• MAJOR STRUCTURES
Nose, pharynx, trachea, lungs/gills
• PHYSIOLOGICAL ROLE
Provides an area for gas exchange between the blood and the
environment
Respiratory
ORGAN SYSTEM ___
• MAJOR STRUCTURES
Heart, blood vessel, blood
• PHYSIOLOGICAL ROLE
Transport nutrients, gases, hormones, metabolic wastes, assist in
temperature contro
Circulatory