*BIOLOGY LECTURE EXAM 3* Flashcards
What is the forth type of biological molecule and what does DNA stand for?
Nucleic Acid
Deoxyribose Nucleic Acid
Draw and label a nucleotide.
ON NOTES!
What did Rosalind Franklin do to contribute to the discovery of DNA structure?
Took photo 51 that showed that DNA was double helix
What components make up chromatin?
DNA & histone proteins
Draw and label the two classes and four type of nitrogenous bases in DNA?
ON NOTES!
Draw and label a small section of DNA with four different base pairs?
ON NOTES!
Whose rules are you following when your paring up these nitrogenous bases?
Chargaff
Why does DNA replication occur?
Cell is about to divide, so both cells have the same amount of DNA
What are the three stages of DNA replication?
Initiation, Elongation, & Termination
Where do origin of replication occur along the double helix and why?
Areas that are rich in adenine and thymine because they require less energy to break apart
What enzyme unwinds the DNA and what does it need to work?
Helicase & ATP
What enzyme cuts, repairs, and alleviates the stress of supercoils?
Topoisomerase
Why are these enzymes (Topoisomerase) important from a medicinal perspective?
Because antibiotics target topoisomerase
What does DNA polymerase type III need to synthesize new DNA? What is the only direction that it can do this in?
It needs a 3’ OH of RNA primer; 5’ to 3’
Describe the initial difference between the leading strand and the lagging strand of the DNA replication fork?
The leading strand is made up of one RNA primer and a continuous new strand of DNA; the lagging strand is made up of RNA primers and DNA stretches called Okazaki fragments.
What enzyme cuts out RNA primers and inserts new DNA nucleotides in their place?
DNA Polymerase Type I