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Derm MSL/Tremfya > Biologics Review > Flashcards

Biologics Review Flashcards

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Dermatology Board Prep flashcards
1
Q

Infliximab target

A

TNF

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2
Q

Rituximab target

A

CD20

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3
Q

Ixekizumab target

A

IL-17A

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4
Q

Natalizumab

A

mucosal and endothelial adhesion molecules

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5
Q

Tildrakizumab-asmn

A

p-19 subunit of IL-23

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6
Q

Toclizumab

A

IL-6 receptor

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7
Q

Vedolizumab

A

mucosal adhesion molecule

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8
Q

Adalimumab

A

TNF

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9
Q

Brodalumab

A

IL-17RA

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10
Q

Guselkumab

A

p-19 subunit of IL-23

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11
Q

Sarilumab

A

IL-6 receptor

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12
Q

Golimumab

A

TNF

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13
Q

Secukinumab

A

IL-17A

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14
Q

Ustekinumab

A

p40 subunit of IL-12 and IL-23

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15
Q

Certolizumab

A

TNF

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16
Q

Abatacept

A

CD80 and CD86

17
Q

Etanercept

A

TNF

18
Q

Guselkumab binds to the p__ subunit of IL-__; inhibiting its interaction with the IL-__ receptor, thus inhibiting the release of proinflammatory cytokines and chemokines.

A

19, 23, 23

19
Q

What are the 3 types of recombinant antibody fragments?

A

Fragment of antigen binding (Fab), Single chain variable fragments (ScFv), 3rd generation (3G molecules)

20
Q

Certolizumab is an example of what?

A

Fab

Derm MSL/Tremfya (8 decks)

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