biologics 3 prefilled syringes

Question 1

are prefilled syringes, pens, and autoinjectors formulations or dosage forms?

Answer 1

NO NONONON they are medical devices

Question 2

these devices are called

Answer 2

COMBINATION PRODUCTS

Question 3

ADVANTAGES of pre-filled syringes, pens, and autoinjectors

Answer 3

ease of use, convinence
easier to transport than vial and syringe
discrete
increased patient compliance
reduced risk of dosage error
reduced risk of product contamination

Question 4

DISADVANTAGES of pre-filled syringes, pens, and autoinjectors

Answer 4

higher cost than vial plus syringe
cannot mix two drugs
drug waste due to priming
greater surface to volume ration, presence of lubricants, can induce aggregation of protein drugs

Question 5

common features of prefilled syringes, autoinjectors, pens

Answer 5

drug solution
needle
piston or plunger
housing