Biological Treatment for OCD Flashcards
see labeled diagram of how neurotransmitters work on showbie
What does SSRI stand for
Selective Serotonin Reuptake Inhibitors
What does SSRI do
Work on increasing certain neurotransmitters in the brain by preventing the re-absorption of serotonin
By preventing the re-absorption of serotonin, SSRIs effectively increase the levels of serotonin in the synapse & thus continue to stimulate the post-synaptic neuron
Who is SSRI given to
People with depression to help increase mood
Biochemical factors of SSRI
- Insel (1991), SSRIs can reduce symptoms of OCD in 50-60% of cases
- Zohar et al. (1996) found that SSRIs can alleviate symptoms (anxiety) in 60% of patients with OCD
When are drugs used
- Drugs are often used alongside cognitive-behavioural therapy (CBT)
- The drugs reduce the sufferers emotional symptoms, sa anxiety or depression
- This means that the patient can then engage more effectively w CBT
- Some sufferers may response best to CBT alone w/o the need for medication
Alternative to SSRIs
Tricyclics - an older type of antidepressant that has same effect on serotonin as SSRIs
SNRIs - serotonin-noradrenaline reuptake inhibitors. 2nd line of defence for patents who do not response well to SSRIs
NASSAs - noradrenaline & specific serotonergic antidepressants
Evaluations (PROS)
Drug therapy is effective at tackling OCD symptoms - there is clear research to suggest that SSRIs are effective in reducing the severity of OCD symptoms (Soomro, 2009)
Drugs are cost-effective & non-disruptive - drug treatments are cheap in comparison to psychological treatments and, unlike psychotherapy, they are non-disruptive to patient’s lives
Evaluations (CONS)
- Drugs can have side-effects
- Unreliable evidence for drug treatments
- Some cases of OCD follow trauma
Evaluations (CONS): Drugs can have side-effects
- Although the use of drugs is effective for most, a significant minority receive no benefit and/or may suffer side-effects: weight gain, sexual dysfunction, loss of memory.
- Coming off a drug is a slow process in which the dosage has to be gradually reduced over a period of 6 months - risk of relapse
Evaluations (CONS): Unreliable evidence for drug treatments
- If drug companies sponsor the research they may decide to suppress any results that do not support the drug they are marketing
- Currently, many drug companies do not publish all of their results & may indeed be supressing evidence. This suggests that the data on the effectiveness of drugs may not be trustworthy
Evaluations (CONS): Some cases of OCD follow trauma
- Although OCD is widely believed to be biological in origin, it is also accepted that OCD can have different causes.
- There is a case for proposing that cases of OCD where there is no family history of OCD, but there is a relevant life event, should be treated differently from those where there is a family history & no trauma. It may be that for these cases drugs are not appropriate