biological therapy for schizophrenia Flashcards

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1
Q

what is the most common treatment for schizophrenia

A

antipsychotic drugs

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2
Q

define antipsychotic drugs

A

used to reduce the intensity of positive symptoms of schisophrenia.

may be required in short of long term.

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3
Q

how can Antipsychotics be divided

A

typical (traditional)
atypical (newer, second-generation) drugs.

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4
Q

define typical antipsychotics.

A

e.g. chlorpromazine - tablets, syrup and injections.

been around since 1950’s

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5
Q

how dose chlorpromazine work

A

work by acting as antagonists in the dopamine system and aim to reduce the action of dopamine

Dopamine antagonists work by blocking dopamine receptors in the synapses in the brain, reducing the action of dopamine.

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6
Q

how dose chlorpromazine reduce hallucinations

A

because the antagonist effect normalises neutrasmission in key areas of brain.

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7
Q

what other effects dose chloropazamine have

A

sedation effect.

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8
Q

define atypical antipsychotics

A

aim to develop newer antipsychotics to maintain and improve suppression of symptoms and side effects of the drugs.

Clozapine - used since the 1970s

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9
Q

how dose clozapine work

A

binds to dopamine reception but also acts on serotonin and glutamate receptors

drug was more effective than typical antipsychotics

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10
Q

what dose clozapine help in symptoms.

A

reduces depression and anxiety in patients as well as improving cognitive functioning.

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11
Q

define risperiodne

A

drug as effective as clozapine but without serious side effects.

developed because clozapine was involved in the deaths of some patients from a blood condition

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