biological therapy for schizophrenia Flashcards
what is the most common treatment for schizophrenia
antipsychotic drugs
define antipsychotic drugs
used to reduce the intensity of positive symptoms of schisophrenia.
may be required in short of long term.
how can Antipsychotics be divided
typical (traditional)
atypical (newer, second-generation) drugs.
define typical antipsychotics.
e.g. chlorpromazine - tablets, syrup and injections.
been around since 1950’s
how dose chlorpromazine work
work by acting as antagonists in the dopamine system and aim to reduce the action of dopamine
Dopamine antagonists work by blocking dopamine receptors in the synapses in the brain, reducing the action of dopamine.
how dose chlorpromazine reduce hallucinations
because the antagonist effect normalises neutrasmission in key areas of brain.
what other effects dose chloropazamine have
sedation effect.
define atypical antipsychotics
aim to develop newer antipsychotics to maintain and improve suppression of symptoms and side effects of the drugs.
Clozapine - used since the 1970s
how dose clozapine work
binds to dopamine reception but also acts on serotonin and glutamate receptors
drug was more effective than typical antipsychotics
what dose clozapine help in symptoms.
reduces depression and anxiety in patients as well as improving cognitive functioning.
define risperiodne
drug as effective as clozapine but without serious side effects.
developed because clozapine was involved in the deaths of some patients from a blood condition