biological psychology Flashcards
evidence for drugs affecting brain functioning
- Van de Oever- found changes in the medial prefrontal cortex in rats with heroin addictions.
Evidence of limbic system in aggression
Charles Whitman- found to have a cancerous tumour in his hypothalamus near his amygdala. School shooting at the University of Texas.
Coccaro et al- studied a group of people with intermittent explosive disorder using FMRI (pictures of threatening and non threatening stimuli). Compared to control group, Ps who had IED had a greater amount of activity in their amygdala when they saw threatening stimuli. Also had lower levels of activity in PFC which may have meant it was harder to inhibit amgydala.
Evidence for prefrontal cortex and aggression
Case study- Phineas Gage who suffered accidental damage to his PFL. Went from a quite, sober, nice family man to an aggressive, irritable drunk. Evidences how the PFC may be involved in moderation of our aggressive or violent behaviour.
CAT scan- Grafman et al- studied veterans in the Vietnam war. Found that veterans with structural damage to PFC were more aggressive than those with structural damage to other areas
Raine et al- studied 41 violent murderers pleading NGRI and found that they had brain dysfunction previously implicated in violent behaviour such as the amygdala and PFC.
Evidence for neurotransmitters and aggression
Clinical drug studies- role of serotonin in aggression. In clinical studies, antidepressants which raise serotonin levels, SSRIs, also tended to reduce irritability and reactive aggression.
Ferrari et al- studied the link between neurotransmitters and aggression in rats. Allowed rats to fight at the same time everyday by introducing an intruder rat. On the 11th day they did not introduce an intruder rat and measured levels of seratonin and dopamine in the brain. They found that as the rats were anticipating a fight, they had lower levels of seratonin in the brain.
evidence for testosterone and aggression
Wagner et al- observed aggression levels in Mice and noticed that after castration aggression levels dropped. When the castrated mice were reinjected with testosterone their aggression levels gradually rose back up to pre castration levels. This provides evidence for how testosterone causes aggression.
Dabbs et al- measured the aggression levels of 89 male prisoners who had committed violent and non violent crimes. Found that VIOLENT prisoners tended to have higher testosterone levels than non violent prisoners
Gender differences in aggression levels
Maccoby and Jacklin 1974- undertook many different lab experiments and field experiments in different social classes and various cultures which concluded than boys are consistently more aggressive than girls.
Issue and debate- (gender) research perpetuates differences between men and women. Research may support or perpetuate gender stereotypes that are oversimplified or exaggerated. Women are also capable of committing violent crimes.
Gottesman and Shields twin study APRC
Aimed to distinguish whether schizophrenia had a biological basis. They identified 57 schizophrenic patients that were members of a twin pair and tracked down the other twin. The twins were split into 4 categories (both twins were diagnosed, cotwin was diagnosed with a similar disorder, cotwin was diagnosed with a disorder not similar to schizophrenia and while proband had schizophrenia cotwin was healthy)
Results: concordance rates were higher in females than males. Concordance rates for severe schizophrenia was 75% for MZ twibut only 24% for DZ twins.
Conclusions: suggest schizophrenia does have a biological genetic basis and is influenced by a persons genes. However, the concordnace rate for MZ schizophrenia was not 100% so it may suggest social factors may have an effect
Ludeke et al APRC
Aim: to determine if peoples personalities could be influenced by their genes. The researchers looked at traditionalism, authoritarianism and religiousness by examining the attitudes of MZ and DZ twins separated at birth.
Procedure: Researchers studied 66 MZ twins and 56 DZ twins separated at birth and reunited. Ps were members of the Minnesota Study of Twins Reared apart group. They filled in various self report measures.
Results: strong correlations were found across all in MZ twins while only conservatism scored strongly for DZ twins.
Conclusions:
Genes do not have an influence on peoples attitudes towards traditionalism.
Cortisol and aggression explanation and evidence
Low cortisol levels appear to be linked with high levels of aggression.
Barzman et al- found that low levels of cortisol in the saliva were linked to a higher number of aggresive incidents in psychiatric patients.
Wilson and Daly- evolution and aggression
Proposed that status competition is a way of explaining the evolutionary advantage of male aggression. Men will compete in risky activities such as violence to attract females, gain higher status and increase chances of successfully reproducing.
evidence for catharsis (freud)- Megargee and Mendelsohn
Aimed to see if there was a link between aggression and personality types. People that were interviewed were given personality tests. They found that these criminals had repressed their anger so much that it had just exploded. They concluded that if people do not let their aggression out in small amounts they will be unable to control it.
evidence against catharsis (freud)- Bushman et al
In his study of Catharsis in aggression found that p’s who had engaged in catharsis by venting their anger and aggression were actually more aggressive than those who did nothing
describe the process of synaptic transmission (3)
An electrical impulse travels along the pre-synaptic neuron (1). The impulse reaches the synaptic vesicles to
release a neurotransmitter (1). These diffuse across the synaptic gap and attach receptors (1)
how does cocaine work?
Cocaine works by blocking the transporter receptors on the presynaptic dopamine neurons in the Ventral Tegmental Area (VTA). As a result the pre-synaptic neurons do not re-uptake dopamine, therefore dopamine remains in the synaptic cleft for longer. This prolongs and intensifies the stimulation of the post-synaptic neuron. Because the VTA activates the nucleus accumbens, the user experiences euphoria
Explain how FMRI works
Looks at neural activity in the brain. FMRI detects the rate at which oxyhaemoglobin becomes deoxyhaemoglobin using BOLD contrast imaging. If an area has a high BOLD contrast imaging then it can be inferred that this area of the brain is used in the behaviour observed. The MRI scanner produces a strong magnetic around the participant. This causes molecules in the magnetic field to move in a slightly different way and release radio-waves which the scanner can then detect.
For example, Caccoro used FMRI to look at activity levels of the amygdala in people with intermittent explosive disorder.