Biological Molecules Pt2 Flashcards
What are amino acids
The monomer from which proteins are made
What is the structure of an amino acid
R
H2N — C — COOH
H
What is the structure of an amine group
NH2
What is the structure of a carboxyl group
COOH
What does the R represent in an amino acid
The side chain, each one has a different one
What reaction joins 2 amino acids together and what is formed
Condensation reaction forms a peptide bond
What is a dipeptide
Condensation reaction between 2 amino acids
What is a polypeptide
Condensation of many amino acids
Functions of protein
- Enzymes - functional proteins
- Blood clotting - defence proteins
- Hormones
- Antibodies
What is primary structure of a protein
The order of amino acids (a chain), changing one may alter properties completely
What is the secondary structure of a protein
When a polypeptide folds a fully functional protein is produced :
1. Alpha helix
2. Beta pleated sheet
Bonds = hydrogen bonds between - charge on carboxylic acid groups and + charge on amino acids
What is the tertiary structure of a protein
The a-helix or b-pleated sheet fold further to give a unique tertiary structure held together by:
1. Hydrogen bonds between r groups
2. Hydrophobic interactions
3. Ionic bonds (strong)
4. Disulphide bridge (string)
What is the quaternary structure of protein
When more than 1 polypeptide chain is bound together
What are the 2 types of quaternary structure
- Globular - e.g haemoglobin
- Fibrous- e.g collagen (triple helix)
What is a conjugated protein
A protein to which another chemical group is attached e.g lipoprotein
Biuret test
Add biuret solution into solution if protein present blue —> purple
Function of dna
Holds genetic information
Function of rna
Transfers genetic info from dna to ribosomes
What are rna and dna polymers of
Nucleotides
What makes up a nucleotide
- pentose
- nitrogen containing organic base
- phosphate group
Components of a dna nucleotide
Deoxyribose, phosphate group and one of organic bases:adenine, thymine, guanine or cytosine
Components of an rna nucleotide
Ribose, phosphate group, of of organic bases: adenine, uracil, guanine, cytosine
What does a condensation reaction between 2 nucleotides form
A phosphodiester bond
What is a dna molecule
A double helix with 2 polynucleotide chains held together by hydrogen bonds between specific complementary base pairs