Biological Molecules Pt2 Flashcards

1
Q

What are amino acids

A

The monomer from which proteins are made

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2
Q

What is the structure of an amino acid

A

R

H2N — C — COOH

         H
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3
Q

What is the structure of an amine group

A

NH2

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4
Q

What is the structure of a carboxyl group

A

COOH

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5
Q

What does the R represent in an amino acid

A

The side chain, each one has a different one

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6
Q

What reaction joins 2 amino acids together and what is formed

A

Condensation reaction forms a peptide bond

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7
Q

What is a dipeptide

A

Condensation reaction between 2 amino acids

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8
Q

What is a polypeptide

A

Condensation of many amino acids

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9
Q

Functions of protein

A
  1. Enzymes - functional proteins
  2. Blood clotting - defence proteins
  3. Hormones
  4. Antibodies
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10
Q

What is primary structure of a protein

A

The order of amino acids (a chain), changing one may alter properties completely

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11
Q

What is the secondary structure of a protein

A

When a polypeptide folds a fully functional protein is produced :
1. Alpha helix
2. Beta pleated sheet
Bonds = hydrogen bonds between - charge on carboxylic acid groups and + charge on amino acids

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12
Q

What is the tertiary structure of a protein

A

The a-helix or b-pleated sheet fold further to give a unique tertiary structure held together by:
1. Hydrogen bonds between r groups
2. Hydrophobic interactions
3. Ionic bonds (strong)
4. Disulphide bridge (string)

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13
Q

What is the quaternary structure of protein

A

When more than 1 polypeptide chain is bound together

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14
Q

What are the 2 types of quaternary structure

A
  1. Globular - e.g haemoglobin
  2. Fibrous- e.g collagen (triple helix)
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15
Q

What is a conjugated protein

A

A protein to which another chemical group is attached e.g lipoprotein

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16
Q

Biuret test

A

Add biuret solution into solution if protein present blue —> purple

17
Q

Function of dna

A

Holds genetic information

18
Q

Function of rna

A

Transfers genetic info from dna to ribosomes

19
Q

What are rna and dna polymers of

A

Nucleotides

20
Q

What makes up a nucleotide

A
  • pentose
  • nitrogen containing organic base
  • phosphate group
21
Q

Components of a dna nucleotide

A

Deoxyribose, phosphate group and one of organic bases:adenine, thymine, guanine or cytosine

22
Q

Components of an rna nucleotide

A

Ribose, phosphate group, of of organic bases: adenine, uracil, guanine, cytosine

23
Q

What does a condensation reaction between 2 nucleotides form

A

A phosphodiester bond

24
Q

What is a dna molecule

A

A double helix with 2 polynucleotide chains held together by hydrogen bonds between specific complementary base pairs

25
What is an rna molecule
A relatively short polynucleotide chain
26
Why is dna a stable molecule
1. Phosphodieseter backbone protects the more reactive bases 2. Hydrogen bonds link the base pairs, forming bridges between the phospodiester upright strands
27
Structure and function of dna
1. Stable molecule so passes from generation to generation without much change 2. 2 strands only joined by h bonds so can easily be separated during dna replication 3. Extremely large molecule so carry’s lots of info 4. Helical shape means genetic material is protected 5. Base pairing means dna is able to replicate and transfer info as mRNA
28
Differences between rna and dna
- rna single stranded dna double - rna uracil dna thymine - rna ribose dna deoxyribose - rna no h bonds dna h bonds - rna no complemtary base pairing dna does
29
Which bases are larger and how many h bonds do they have
G and a larger, c and t smaller Gc 3h bonds At 2 h bonds
30
What is ATP made up of
A base (adenine) a sugar (ribose) 3 inorganic phosphate groups
31
What happens when ATP is hydrolysed
ATP + WATER —> ADP +Pi + energy
32
What enzyme catalysises the hydrolysis of atp
ATP hydrolase
33
What is atp used for
Main source of energy to carry out processes within cells
34
How can the inorganic phosphate that is released during the hydrolysis of ATP be used
To phosphorylate other compounds, making them more reactive
35
3 ways of phosphorylation
1. Photophosphorylation (in chlorophyll containing plant cells during photosynthesis) 2. Oxidative phosphorylation (in animals + plants during respiration) 3. Substrate level phosphorylation
36
How is ATP resynthesised
The condensation of ADP and Pi and is catalysed by ATP synthase during photosynthesis or respiration