Biological membranes Flashcards
roles of membranes
- partially permeable barriers between the cell and its environment, between organelles and the cytoplasm within organelles.
- site of chemical reaction
- site of cell signalling
- compartalisation: provides specific conditions for certain reactions to occur
fluid mosaic model
proposed that the fabric of the membrane consisted of a phospholipid bilayer with proteins floating in it making up a mosaic pattern. The lipid molecules can change places with each other, and some of the proteins may move, giving fluidity
role of components in the membrane
phospholipid bilayer- allows the membrane to be partially permeable
cholesterol- restricts the lateral (sideways) movement of other molecules in the membrane regulating the fluidity.
peripheral proteins - provides mechanical support, or are connected to proteins or lipids to make glycoproteins and glycolipids which function is cell recognition, as receptors.
integral proteins- protein carriers or channel proteins involved in the transport of molecule across the membrane.
how do drugs and hormones move into a cell
they bind to the membrane-bound receptors
why is it important that the membrane fluidity is controlled?
so that at high temperatures the membrane is less fluid therefore preventing water and dissolved ions leaking out of the cell.
How does an increase in temperature affect the cell membrane structure?
as temperature increases, the phospholipids gain kinetic energy meaning thy will move more. This causes gaps to appear between the phospholipids so the membrane will become more permeable. at high temperatures the proteins in the membrane will denature,
How does a decrease in temperature effect the cell membrane permeability?
when water freezes it expands and forms ice crystals which pierce and break the cell membrane
how does ethanol and detergents affect the cell membrane permeability?
they both dissolve the phospholipid bilayer making the membrane more permeable
passive transport
substances that can be exchanged across cell membranes without requiring metabolic energy from cells(no ATP)
diffusion
the net movement of molecules from an area of higher concentration to an area of lower concentration
facilitated diffusion
the net movement of molecules from an area of higher concentration to an area of lower concentration across a partially permeable membrane via protein channels or carriers
what happens at an equilibrium?
the particles are still moving freely and randomly but there is no net movement
factors that affect the rate of diffusion
temperature- as temperature increases, molecules have more kinetic energy so rate of diffusion increase visa versa.
diffusion distance- the thicker the membrane the slower the rate of diffusion
surface area-more diffusion takes place across larger surface areas
concentration gradient- the steeper the concentration gradient the faster diffusion
osmosis
the movement of water molecules from a region of higher water potential to a region of lower water potential through a partially permeable membrane
water potential of water
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