BIOLOGICAL EXPLANATIONS

Question 1

GENETICS

Answer 1

• schizophrenia does run in families

GOTTESMAN ET AL

Question 2

DOPAMINE HYPOTHESIS

Answer 2

• The original dopamine hypothesis stated that schizophrenia suffered from an excessive amount of dopamine.

Question 3

HYPERDOPAMINERGIA

Answer 3

• high dopamine level in brain subcortex. Excess dopamine in Broca’s area is asscoiated with speech poverty and auditory hallucinations

Question 4

HYPODOPAMINERGIA

Answer 4

• new model; low dopamine level in brain cortex.

GOLDMAN-RAKIC ET AL

• low dopamine level in prefrontal cortex
• negative symptoms

Question 5

Evidence for genetic susceptibility

Answer 5

• Gottesman table

TIENARI ET AL
- adopted children with history of SZ are at risk of developing