BIOLOGICAL APPROACH TO EXPLAINING OCD Flashcards

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1
Q

how many explanations are there for OCD in the biological approach?

A

2

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2
Q

what are the two explanations for OCD?

A

genetic

neural

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3
Q

what are candidate genes in OCD?

A

a gene of interest when looking a particular behaviours/characteristics that could be inherited

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4
Q

what are family studies?

A

family studies are when you look at similarities within families for example if one relative has OCD what at the chances of others

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5
Q

what are chromosomes?

A

23 pairs of chromosomes, 46 in total

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6
Q

what are genes?

A

information about a part of you

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7
Q

what is DNA?

A

a chemical structure

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8
Q

what are concordance rates?

A

the rate of similarity e.g. in twin studies

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9
Q

what are two candidate genes that can lead to the inheritance of OCD?

A

COMT

SERT

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10
Q

what does the COMT gene regulate?

A

levels of dopamine

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11
Q

in OCD, are the levels of dopamine increased or decreased?

A

they are increased

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12
Q

who supports that the COMT gene can lead to higher levels of dopamine?

A

Tukel who says that a variation/mutation in the COMT gene can lower activity and increase levels of dopamine

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13
Q

what does the SERT gene regulate?

A

the levels of serotonin

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14
Q

are levels of seratonin increase or decreased on OCD?

A

decreased

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15
Q

who has research to support the SERT gene leading to the inheritance of OCD?

A

Ozaki found that a mutation of SERT gene in unrelated families with 6/7 members with OCD had lower levels of seratonin

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16
Q

OCD is…

A

polygenic

17
Q

what does polygenic mean?

A

means many genes

18
Q

who found that there may be over 230 genes involved in the inheritance of OCD?

A

Taylor

19
Q

what are neural explanations for OCD?

A

serotonin

decision making system

20
Q

how does the neural explanation describe serotonin?

A

low levels of serotonin lower mood

21
Q

what are the neurotransmitters responsible for?

A

responsible for relaying information from one neuron to another

22
Q

what occurs if there are lower levels of serotonin than normal?

A

no transmission of mood relevant information

23
Q

what is impaired in the frontal lobes?

A

decision making systems

24
Q

what are the frontal lobes responsible for?

A

logical thinking and decision making

25
Q

what part of the brain is dysfunctional in OCD according to the neural explanation?

A

the paragippocampal gyrus

26
Q

what is the parahippocampal gyrus responsible for?

A

processing unpleasant emotions