Biological Flashcards

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1
Q

1) What are the parts of a neuron?

A
1) Dendrite
Nucleus
Axon
Myelin sheath
Node of Ranvier
Schwann Cell
Axon Terminal
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2
Q

1) What is Action Potential?

A

1) The method by which the electrical impulse passes down the axon of the neuron to stimulate the release of neurotransmitters (chemical messengers) to another neuron.

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3
Q

1) What are the three types of neurons?

A

1)
Sensory Neurons - Carry messages along PNS to CNS. They have long dendrites and short axons.

Motor Neurons - Carry messages from the CNS, along nerves in the PNS to effectors in the body. They have short dendrites and long axons.

Relay Neurons - Connect sensory and motor neurons together, and also connect to other relay neurons, only found in CNS. Short dendrites and short axons.

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4
Q

1) What are Excitatory Neurotransmitters?

2) What’s an example?

A

1) Excitatory neurotransmitters cause the axon to become less negative. Therefore, excitatory neurotransmitters increase the likelihood of an action potential firing.
2) Dopamine

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5
Q

1) What are Inhibitory Neurotransmitters?

2) What’s an example?

A

1) Inhibitory neurotransmitters cause the axon to become more negative. Therefore, inhibitory neurotransmitters decrease the likelihood of an action potential firing.
2) Serotonin

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6
Q

1) Communication within a neuron is ______?

2) Communication between neurons is ______?

A

1) Electrical

2) Chemical

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7
Q

1) What is Synaptic Transmission?

A

1) When an action potential reaches the presynaptic terminal, it causes the vesicles to fuse with the presynaptic membrane and release their contents (neurotransmitters) into the synaptic cleft.

Once the neurotransmitters are in the synaptic cleft they diffuse across and bind to the receptors on the postsynaptic neuron. The chemical signal is converted back into an electrical signal in the postsynaptic neuron, which may fire another AP.

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8
Q

1) What happens to neurotransmitters that remain in the synaptic cleft?

A

1) They are either reabsorbed into the presynaptic neuron by an uptake pump, this is a process called reuptake and means the neurotransmitters can be used again.
Or enzymes break down the neurotransmitters within the synaptic cleft.

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9
Q

1) What does the neurotransmitter Serotonin do?

A

1) Associated with mood control in the limbic system of the brain. Involved in feelings of hunger and pain.

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10
Q

1) What does the neurotransmitter Dopamine do?

A

1) Emotional and cognitive functioning. Reinforcement in learning and addiction.

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11
Q

1) What does the neurotransmitter Acetylcholine do?

A

1) Involved in muscle contractions so is key to motor functioning. Also important for cognitive functions such as attention, memory and learning.

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12
Q

1) What does the neurotransmitter Noradrenaline do?

A

1) Emotion and mood control- as well as sleeping.

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13
Q

1) Explain the reward pathway

A

1)The brain contains a reward pathway which causes us to experience a pleasant and rewarding feeling.

Behaviour + nice feeling = continued/repeated behaviour

The reward pathway has evolved – it is adaptive for us to feel good after eating high-calorie food for example, as it ensures we store enough fat on our bodies in preparation for periods of famine.
Drugs hijack this reward system and produce pleasurable feelings without any adaptive functioning, e.g. cocaine floods the synapses with excess levels of dopamine as it blocks the molecules on presynaptic neuron involved in its reuptake.

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14
Q

1) Explain the effects of Cocaine

A

1)Increases the activity in the dopamine pathway by blocking the reuptake of dopamine, it mimics the structure of dopamine binding to the uptake pumps on the presynaptic neuron.

As a result the synapse is flooded with excess quantities of dopamine, available for binding with postsynaptic receptors. Excess of dopamine creates the euphoric “high” that the person feels when taking cocaine.

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15
Q

1) Explain the effects of Nicotine

A

1)Targets aspects of the dopamine pathway increasing the amount and transmission of dopamine by blocking the enzyme that breaks it down. It also mimics acetylcholine and binds to nicotinic receptors stimulating them.

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16
Q

1)Explain the effects of Alcohol

A

1) Has a depressant effect on the nervous system; it acts to inhibit neural transmission by increasing the action of GABA (inhibitory neurotransmitter), this makes memory less efficient (slows down neural communication). But does increase serotonin which makes individuals feel happier.

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17
Q

1) Your brain controls/processes your body _________

2) Which means…

A

1) Contralaterally

2) The right side of your brain is responsible for controlling the left side of your body and vice versa.

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18
Q

1) The two hemispheres are linked by a “bridge” of nerve fibers called the ________?

A

1) Corpus Callosum

19
Q

What is the role of the frontal cortex?

A

1) It is the location for awareness of what we are doing (rational thinking and decision making),
-Governs social interactiona and regulates behaviour
-Makes up 40% of the cerebral cortex in humans.

20
Q

What is the role of the temporal lobe?

A

The temporal lobe handles most of our memory functions, understanding language and processing auditory information

21
Q

What is the role of the occipital lobe?

A

The occipital lobe is at the back of the brain, but it processes sight, object and facial recognition.

22
Q

What is the role of the parietal lobe?

A

The parietal lobe controls language but also specialises in touch and directing bodily movements.

23
Q

What is aggression?`

A

A behaviour that is intended to cause injury, both psychological or physical

24
Q

What is the prefrontal cortex’s link to aggression?

A
  • Has connections to amygdala and hypothalamus.

- Damage to the area leads to problems with anger management, irritability and impulse control.

25
Q

What is the hypothalamus’ link to aggression?

A
  • Maintains homeostasis through regulation of hormones

- Linked to aggressive behaviour via production of testosterone

26
Q

What is the amygdala’s link to aggression?

A
  • Centre for emotion, behaviour and motivation
  • Plays a role in responding to threats and challenges
  • Connects to prefrontal cortex and this could lead to expression of aggression
27
Q

One strength evaluation point to support arguments of drugs effects on the brain

A

-There is lots of evidence supporting the arguments.

  • Olds & Milner (1954) found a pleasure centre in rat brains.
  • The rats pressed the lever up to 2000 times in an hour.
  • Dopamine was the source as the rats wanted to feel the feeling they did when the press it.
  • Straiker et al (2012) looked at the effect of cannabis and found an effect in the hippocampus of mice.
  • They showed similar addictive behaviour to humans when dosed,
  • This is reliable research with careful controls

-Strength because the rats got addicted. This proves dopamine was released and addiction is real.

28
Q

One weakness evaluation point to support arguments of drugs effects on the brain

A
  • There’s a complexity in how transmission works in the brain which is hard to capture.
  • Cannabis limits hippocampal activity but also leads to more dopamine activity .
  • Having one explanation for the mode of action of a recreational drug seems simplistic

-Weakness because human brains are more complex

29
Q

AO1 of the classic study - (R et al)

A

A - To investigate whether ppt pleading NGRI would show brain dysfunctions in areas of the brain associated with violence

All ppt remained med free for 2 weeks prior to PET scan.

P - Two groups of 41 people : 39 males and 2 females in each group.
Experimental group- Criminals with convictions for murder/manslaughter who were being tested to gain evidence supporting NGRI.
Consisted of 6 schizophrenic, 23 organic brain damage and the rest with other disorders.

Control group - Matched with experimental group on age and gender. All screened for general health.

Ppt were given continuous performance tasks (CPT) to completed . They did this for 10 minutes before being injected with FDG. After 32 minutes, a PET scan was completed to see which brain areas were being used.

F- More activity on the right side of the brain

  • Less activity on the left side of the brain
  • Less activity in prefrontal cortex and corpus callosum.

C - Brain activity of murders was significantly different from brain structure /activity of non-murderers.

30
Q

A03 of classic study - (R et al)

A

Strength - High controlled study

  • Evenly matched ppt on age, sex and mental disorders
  • Standardised procedures used (32 min CPT was consistent)
  • Ppt were drug tested to ensure effects of drugs wouldn’t confound brain scan
  • Findings on the relationship between brain regions and violence can be fairly measured

Weakness - Small subject of violent criminals

  • 41 criminals who pleaded insane
  • This doesn’t provide a conclusive explanation of violent behaviour as a whole.
  • e.g. it doesn’t explain behaviour of raging alcoholics but not murderers or murderers who didn’t plead insane.
  • The findings can’t be used to explain all types of aggressive violent behaviour
31
Q

What’s the difference between structural and functional imaging?

A

Structural imaging ( e.g. CT scan) produces a static image whereas functional imaging (PET Scan, MRI) produces images in action.

32
Q

AO1 and AO3 of CT scans

What does CT scan stand for?

A

(Computed tomography)
-Use X-ray beams at different angles
-A computer compiled the images to create cross-sectional images showing structure not function.
Used to see major structural problems like a tumor.

32
Q

AO1 and AO3 of CT scans

What does CT scan stand for?

A

(Computed tomography)
-Use X-ray beams at different angles
-A computer compiled the images to create cross-sectional images showing structure not function.
Used to see major structural problems like a tumor.

S: Quick to conduct and gives accurate details of brain structure

W: No detail about brain function
W: Low resolution images
W: Potential risks due to X-ray radiation

33
Q

AO1 and AO3 of PET scans

What does PET stand for

A

(Position Emission Tomography)

  • Measures activity in the brain by tracking glucose usage
  • Person injected with radiotracer (FDG) which binds to glucose in the blood
  • More active brain areas need glucose and so will be detected by the scanner.

S: Indicates specific areas in brain involved in the experience.

W: Radioactive tracer may kill or damage cells or cause levels of mutation. Makes the scan invasive compared to fMRI.
Not used on pregnant women

34
Q

AO1 an AO3 of fMRI scans

What does fMRI stand for?

A

(functional magnetic resonance imaging)

  • Uses radiofrequency energy and magnetic field to measure blood oxygen levels in the brain
  • ‘Haemodynamic’ oxygen usage measured by the scan which forms a 3D image by detecting changes in magnetism.

S: High resolution images

W: In order for fMRI , you have to stay still and this may be difficult for some people.

W: Anyone who has a cardiac pace-maker or recent metal surgical implants can’t have fMRI

35
Q

AO1 : What is the role of testosterone in aggression?

A
  • Testosterone is present in all humans, but much higher in males
  • Giammanco et al demonstrated that experimental increases in testosterone are related to more aggressive behaviour in the males of several species
36
Q

AO1 : What is the role of cortisol in aggression?

A
  • Manages stress levels
  • Inhibits aggression
  • Virkkunen reported low levels of cortisol in violent offenders
37
Q

AO3 : Strength of hormones explaining aggression

A

-High control in studies
-Motelica-Heino, Edwards and Roffi found rodents which are castrated show no aggression.
-When they’re injected with testosterone, the aggression re-emerged.
-It shows testosterone made the rats aggressive and this demonstrates cause and effect relationship.
-

38
Q

What are the 4 evolution theories?

A

1) Aggressive gene - MAOA
- Warrior gene, used to survive from our ancestors

2) As a tool to assert dominance/social status
- Helps gain territory, resources and used in hunting

3) For mate retention
- Buss argued males develop strategies for mate retention.
- Prevents rival’s genes being passed on

4) Epigenetics
- Environmental stimuli can cause genetic modifications

39
Q

Psychodynamic explanation of aggression

2 components

A

Eros - Life Instinct

Thanatos- Death Instinct

40
Q

Freud’s personality theory

3 components

A

Id

  • Pleasure Principle
  • Age 0-2
  • No thought of consequences
  • Animalistic
  • In the unconscious

Ego

  • Reality Principle
  • Age 3-5
  • Logical, rational
  • Mostly conscious

Superego

  • Morality Principle
  • Age 5/6
  • Moral, conscious sense of right and wrong
  • After effect (e.g. guilt, shame)
41
Q

AO1 of contemporary study - (B et al)

A

A
- To investigate aggression in monozygotic (MZ) and dizygotic (DZ) twins and see how genetics and the environment affect it.

P

  • Twin Study Design
  • 234 twins from QNTS
  • (44 male MZ, 50 female MZ, 41 male DZ, 32 female DZ)
  • QNTS collected data from 5 months old
  • At 72 months (6 years) data collection stopped
  • Teacher and Peer rating took place
  • They both rated social and physical aggression

F

  • Only 20% (teacher) and 23% (peer) of social aggression was explained by genetic factors.
  • Genetic factors explain physical aggression
  • Non shared environmental factors explained social aggression
  • A significant correlation between social and physical aggression explained by overlapping genetic influences
  • Boys more physically aggressive, girl smore socially aggressive

C

  • Genetic characteristics predispose some children to aggressive behaviour (e.g. poor self-control, irritable temperament)
  • Environmental factors hugely impact aggressive behaviour ( e.g. parental behaviour)
42
Q

AO3 of contemporary study (B et al)

1 S + 1 W

A

Strength:

  • Researchers used ratings of aggression from two sources (teachers + peers)
  • Extremely similar results so results are therefore reliable and valid measure of aggressive behaviour

Weakness:

  • All twin studies are based on equal environment assumption. The assumption states MZ and DZ twins experience similar treatment to the same extent
  • The assumption may be wrong. It’s likely the parents of DZ twins will behave more aggressively towards one than the other because they’re dissimilar
  • Undermines the validity of the twin study method