Biologic drug therapeutics (drugs used in immune diseases) Flashcards
1
Q
What are examples of anti-TNF drugs (TNF inhibitors)?
A
Adalimumab
Infliximab
Etanercept
2
Q
What drug class are adalimumab and infliximab?
A
TNF inhibitors
3
Q
What drug class is tofacitinib?
A
JAK inhibitor
4
Q
What monitoring requirements?
A
Full blood count
renal function- eGFR
LFTSs
Tuberculosis test- if latent TB give chemoprophylaxis first
hepatitis b and c screen
chest x-ray
review at least every 6 months
5
Q
Are brands interchangeable?
A
NO- can’t convert unless prescribed
need record of batch numbers, brand- patients should be on a disease registry
6
Q
What conditions can infliximab be used for?
A
RA
Chron’s
collitis
Psoriasis
Alkolysing spondylitis
7
Q
What is typical dosing of infliximab for RA?
A
30mg/kg at week 0, 2 and 6 and then every 8 weeks thereafter
