biol exam 4 MC

Question 1

_______ mediate most of cell’s functions.
A. Carbohydrates
B. DNA
C. Lipids
D. Proteins
E. RNA

Answer 1

D. Proteins

Question 2

RNA processing does not include _____.
A. Addition of 5’ cap
B. Coding of 5’ UTR
C. Inclusion of specific exons
D. Removal of introns
E. Splicing of primary transcript

Answer 2

B. Coding of 5’ UTR

Question 3

Thymine dimers are indicative of ____.
A. Deletion
B. Frameshift
C. Inversion
D. UV damage
E. Missense

Answer 3

D. UV damage

Question 4

Chromosomal mutation categories include all of the
following, except ____.
A. Deletion
B. Duplication
C. Inversion
D. Missense
E. Translocation

Answer 4

D. Missense

Question 5

Which of the following is not one of the three critical
RNA processing steps in eukaryotes?
A. Splicing
B. Addition of 5’ cap
C. Addition of poly-A tail
D. Addition of Shine-Dalgarno sequence

Answer 5

D. Addition of Shine-Dalgarno sequence

Question 6

An apoenzyme is a protein that may be missing any of
the following, except ____.
A. Cofactors
B. Other protein sub-units
C. Prosthetic groups
D. Core protein

Answer 6

D. Core protein

Question 7

The number of unique proteins made in the human
body is a lot greater than the ~25,000 genes in the
human genome because of _____.
A. 5’ UTR
B. Alternative splicing
C. Selection
D. Fitness
E. Different sigma

Answer 7

B. Alternative splicing

Question 8

Which of the following terms indicates a presence of
histones.
A. Genome
B. Chromatin
C. DNA
D. Regulatory region
E. Phenotype

Answer 8

B. Chromatin

Question 9

____ can create multiple types of proteins from a
single gene.
A. Alternative splicing
B. Polyribosome
C. RNA polymerase
D. tRNA
E. 5’ UTR

Answer 9

A. Alternative splicing

Question 10

A gene has 12 exons. Assume that each exon could be
included or excluded from the mRNA. How many
combinations are possible?
A. 2 + 12
B. 20,000 ^ 10
C. 2 ^ 12
D. 12 ^ 2
E. 2 * 12

Answer 10

D. 12 ^ 2

Question 11

Which of the following is NOT needed to initiate
transcription in bacteria?
A. DNA template
B. Helicase
C. Promoter sequence
D. RNA polymerase
E. Sigma protein

Answer 11

B. Helicase

Question 12

Assume that for the arginine mutation experiment, all
mutants required arginine to grow. This could possibly
mean that _____.
A. Mutations do not determine protein function
B. There are multiple proteins involved in synthesis
of arginine
C. All mutations were in a single gene
D. “One gene, one protein” hypothesis is wrong

Answer 12

C. All mutations were in a single gene

Question 13

Change of a single amino acid in a polypeptide would
be due to _______ mutations.
A. Codon amplification
B. Frameshift
C. Nonsense
D. Silent
E. Missense

Answer 13

E. Missense

Question 14

The Genetic Code is all of the following except _____.
A. Conservative
B. Domain specific
C. Non-overlapping
D. Redundant
E. Unambiguous

Answer 14

B. Domain specific

Question 15

Which of the following statements about spliceosomes
is incorrect.
A. contain snRNPs.
B. contain both proteins and RNA.
C. make a lariat (loop) with the intron sequence.
D. are similar in all species on Earth.
E. remove all introns and sometimes exons as well.

Answer 15

D. are similar in all species on Earth.

Question 16

Which of the following open reading frame (ORF) has
the potential to transcribe a large protein?
A. Does not have an AUG.
B. Has lots of stop codons.
C. Has a stop codon next to an AUG.
D. Has a stop codon far downstream of an AUG

Answer 16

D. Has a stop codon far downstream of an AUG

Question 17

______ mutations alter the amino acids coded by the
downstream codons.
A. Frameshift
B. Missense
C. Nonsense
D. Point
E. Silent

Answer 17

A. Frameshift

Question 18

______ mutations prematurely terminate the
polypeptide chain.
A. Frameshift
B. Missense
C. Nonsense
D. Point

Answer 18

C. Nonsense

Question 19

Progeny from DD x Dd will have ____ of the progeny
showing recessive trait.
A. 0 %
B. 25%
C. 50%
D. 75%
E. 100%

Answer 19

A. 0 %

Question 20

Principle of segregation states that the two _____ will
segregate into two gametes.
A. Proteins
B. Phenotypes
C. Dominance
D. Alleles
E. Genes

Answer 20

D. Alleles

Question 21

Which of the following statements about mRNA
processing in eukaryotes is incorrect.
A. A guanosine is added as a 5’ cap.
B. A string of adenosine is added at the 3’ end.
C. The entire mRNA sequence codes for amino
acids.
D. All the introns are removed.
E. A 5’ UTR sequence may regulate translation.

Answer 21

C. The entire mRNA sequence codes for amino

Question 22

Which of the following is not correct about RNA?
A. RNA is found inside ribosomes
B. RNA can base pair with DNA
C. RNA can function as a catalytic molecule
D. RNA is the hereditary material in some
archaea
E. RNA may have been the first self-replicating
molecule

Answer 22

D. RNA is the hereditary material in some
archaea

Question 23

Principle of independent assortment states that the
_____ will be inherited independently.
A. Two alleles for a given gene
B. Two alleles for different genes
C. Two genes on different chromosomes
D. Two genes on the same chromosome

Answer 23

C. Two genes on different chromosomes

Question 24

In a test cross an individual with a _____ phenotype
will be crossed with an individual with _______
phenotype.
A. Dominant; hybrid
B. Dominant; recessive
C. Recessive; dominant
D. Hybrid; dominant
E. Hybrid; recessive

Answer 24

B. Dominant; recessive

Question 25

This pedigree chart suggests
that the disease is ________. (both mom and dad show the disease)
A. Autosomal dominant
B. Autosomal recessive
C. X-linked dominant
D. X-linked recessive
E. None of the above

Answer 25

B. Autosomal recessive

Question 26

This pedigree chart suggests that the disease is
________. (mom shows dad doesn’t)
A. Autosomal dominant
B. Autosomal recessive
C. X-linked dominant
D. X-linked recessive
E. None of the above

Answer 26

D. X-linked recessive