Biocompatibility Flashcards
variables of biocompatibility of a material
duration, properties, health of host
testing for biocompatibility (IRB) lasts about blank years
40
irb is the blank
institutional review board
testing of biocompatibility can be performed on blank, cell blank, and blank prepared for extraction
animals, cultures, premolars/third molars
adverse response to biomaterial
inflammation
inflammation could be due to these
mutagenicity, allergy, toxicity
cell death, harmful effects like lead
toxicity
part of some bridges that some people are allergic to
nickel
allergic response is when there is a blank reaction and is dose blank
disproportionate, independent
allergic reactions can be of these types
1-4
pulp, periodontal, apical, tongue, buccal or labial mucosa are examples of blank inflammation
local
ingested, inhaled, released at apex, absorption through mucosa, blood or lymph is more related to blank
systemic
the shade of our teeth come from blank
dentin not enamel
bleaching teeth goes through blank and bleaches blank
enamel, dentin
systemic response variables
excretion rate, site of exposure, duration of exposure
electrochemical reaction of materials example
opposing teeth during occlusion creating current
things that can happen to a bio material
corrosion, oxidation, electrochemical, mechanical, digestion
is finish or polish more important
finish
surface characteristics that can affect biocompatibility
texture, oxygen inhibition of reaction, absorption, adhesion, attraction of LPS
immune cells reacting differently to biomaterial
immunotoxicity
cells that are naked nerve endings that are extremely sensitive in the dentin
odontoblast
inflammation can be caused by defective oral blank
anatomy
dentin resin interface of restoration must have no blank
spaces
interface that requires osseointegration and biointegration
implant-bone
testing in the body
in vivo
testing outside the body
in vitro
responsibility of dentist regarding biomaterials
msds (material safety data sheet)
compatible with life
biocompatible