Biochemistry Evals - Lipid oxidation ketogenesis; Acylglycerol and eicosanoids; Lipid transport and storage; Cholesterol

Question 1

Lanosterol to cholesterol except:

Answer 1

shortening of carbon 30 to 25

Question 2

NSAIDS

Answer 2

inhibit PGH synthesis

cooxygenase

Question 3

C27H450H

Answer 3

Cholesterol

Question 4

Decrease 100 mg dietary

cholesterol, decrease 0.13 (true or false)

Answer 4

true

Question 5

7 cycles and 8 acetyl coa

Answer 5

Acetyl coa

Question 6

Beta oxidation produce

Answer 6

1 acetyl coa, 1 FADH2, 1 NADH

Question 7

FA activated to acylcoa

Answer 7

acyl coa synthetase

Question 8

Parent steroid in formation of

cholesterol

Answer 8

lanosterol

Question 9

Role of leukotriene except

Answer 9

induce

sleep

Question 10

APO B 100

Answer 10

LDL

Question 11

Last stage of VLDL

Answer 11

LDL

Question 12

Cholesterol excreted from liver as

Answer 12

bile salts

Question 13

Inhibit PGHS1 and 2

Answer 13

aspirin

Question 14

Carnitine deficiency uncommon

Answer 14

febrile seizure

Question 15

Palmitate

Answer 15

106 ATP

Question 16

Insulin increases the activity of

HMG CoA reductase

Answer 16

true

Question 17

FA oxidation except

Answer 17

carboxylation

Question 18

Biosynthesis of cholesterol

Answer 18

cytoplasm

Question 19

Immediate substrate

Answer 19

acetylc oa

Question 20

cleave alpha and beta

Answer 20

Thiolase

Question 21

Cofactor LCAT

Answer 21

Apo A-I

Question 22

Precursos of arachidonic acid

Answer 22

linoleic

Question 23

Reverse cholesterol transport -

Answer 23

HDL

Question 24

10 yr old girl with carnitine

deficiency can’t produce

Answer 24

fatty acyl

carnitine

Question 25

Ketogenesis - where

Answer 25

liver

Question 26

Prostanoids

Answer 26

prostaglandin and | thromboxane

Question 27

Apolipoprotein in HDL

Answer 27

A

Question 28

Active

Answer 28

FFA

Question 29

Dieatary fats in the intestines

Answer 29

pancreatic lipase

Question 30

Cyclization of squalene

Answer 30

lanosterol

Question 31

Outer mitochondrial membrane | transfer

Answer 31

carnitine palmitoyl | transferase I

Question 32

Most abundant

Answer 32

cholesteryl ester

Question 33

Diacylglycerol + acetyl coa

Answer 33

free acyl coa

Question 34

Insulin activates or promotes | chuchu reductase - true or false

Answer 34

TRUE

Question 35

Glucagon activates or promotes | something reductase - true or false

Answer 35

false

Question 36

Alcohol produces

Answer 36

NADH

Question 37

Lipoprotein lipase cofacto | inhibitorr

Answer 37

CIII

Question 38

Free cholesterol from tissues | plasma HDL transported to liver - true or false

Answer 38

true

Question 39

Role of leukotrienes except

Answer 39

induce sleep

Question 40

Reduction of NADH ketogenesis

Answer 40

beta hydoxybutyryl acetoacetate

Question 41

LPP

Answer 41

18

Question 42

inc HMG-Coa reductase

Answer 42

Insulin

Question 43

``` Hydrolyze arachidonic acid from membrane phospholipids - a. epi, b. thrombin, c. bradykinin d. AOTA ```

Answer 43

AOTA

Question 44

FFA to acyl-coa (enzyme)

Answer 44

acyl-coa | synthetase

Question 45

True of chylomicrons except

Answer 45

predominantly cholesterol (dapat TAG)

Question 46

Predominant plasma lipid

Answer 46

Cholesteryl ester (36%)

Question 47

Most active plasma lipid

Answer 47

Unesterified FA

Question 48

Apo A

Answer 48

HDL

Question 49

Inhibits PLA from forming eicosanoids:

Answer 49

Steroids

Question 50

Oxidation of FA with odd number of Carbon yields?

Answer 50

Acetyl CoA + propionyl

Question 51

TRUE/FALSE: Elevated levels of cholesterol in LDL and VLDL is related with atherosclerosis while high HDL levels have a protective effect.

Answer 51

True

Question 52

Added to diacylglycerol to form TAG

Answer 52

fatty acyl coa?

Question 53

Starting material for ketogenesis:

Answer 53

Acetoacetyl CoA

Question 54

``` Stimulates the release of arachidonic acid from the membrane phospholipid A. Epinephrine B. Thrombin C. Bradykinin D. AOTA ```

Answer 54

D. AOTA

Question 55

Cofactor for lipoprotein lipase

Answer 55

Apo CII

Question 56

Condensation of 6 IPP requires how many ATP

Answer 56

18 ATP

Question 57

Major protein of HDL, activates lecithin: cholesterol acyltransferase, LCAT:

Answer 57

Apo A-1