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BIOCHEMISTRY > Biochemistry Evals - Lipid oxidation ketogenesis; Acylglycerol and eicosanoids; Lipid transport and storage; Cholesterol > Flashcards

Biochemistry Evals - Lipid oxidation ketogenesis; Acylglycerol and eicosanoids; Lipid transport and storage; Cholesterol Flashcards

1
Q

Lanosterol to cholesterol except:

A

shortening of carbon 30 to 25

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2
Q

NSAIDS

A

inhibit PGH synthesis

cooxygenase

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3
Q

C27H450H

A

Cholesterol

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4
Q

Decrease 100 mg dietary

cholesterol, decrease 0.13 (true or false)

A

true

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5
Q

7 cycles and 8 acetyl coa

A

Acetyl coa

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6
Q

Beta oxidation produce

A

1 acetyl coa, 1 FADH2, 1 NADH

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7
Q

FA activated to acylcoa

A

acyl coa synthetase

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8
Q

Parent steroid in formation of

cholesterol

A

lanosterol

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9
Q

Role of leukotriene except

A

induce

sleep

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10
Q

APO B 100

A

LDL

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11
Q

Last stage of VLDL

A

LDL

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12
Q

Cholesterol excreted from liver as

A

bile salts

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13
Q

Inhibit PGHS1 and 2

A

aspirin

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14
Q

Carnitine deficiency uncommon

A

febrile seizure

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15
Q

Palmitate

A

106 ATP

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16
Q

Insulin increases the activity of

HMG CoA reductase

A

true

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17
Q

FA oxidation except

A

carboxylation

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18
Q

Biosynthesis of cholesterol

A

cytoplasm

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19
Q

Immediate substrate

A

acetylc oa

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20
Q

cleave alpha and beta

A

Thiolase

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21
Q

Cofactor LCAT

A

Apo A-I

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22
Q

Precursos of arachidonic acid

A

linoleic

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23
Q

Reverse cholesterol transport -

A

HDL

24
Q

10 yr old girl with carnitine

deficiency can’t produce

A

fatty acyl

carnitine

25
Q

Ketogenesis - where

A

liver

26
Q

Prostanoids

A

prostaglandin and

thromboxane

27
Q

Apolipoprotein in HDL

A

A

28
Q

Active

A

FFA

29
Q

Dieatary fats in the intestines

A

pancreatic lipase

30
Q

Cyclization of squalene

A

lanosterol

31
Q

Outer mitochondrial membrane

transfer

A

carnitine palmitoyl

transferase I

32
Q

Most abundant

A

cholesteryl ester

33
Q

Diacylglycerol + acetyl coa

A

free acyl coa

34
Q

Insulin activates or promotes

chuchu reductase - true or false

A

TRUE

35
Q

Glucagon activates or promotes

something reductase - true or false

A

false

36
Q

Alcohol produces

A

NADH

37
Q

Lipoprotein lipase cofacto

inhibitorr

A

CIII

38
Q

Free cholesterol from tissues

plasma HDL transported to liver - true or false

A

true

39
Q

Role of leukotrienes except

A

induce sleep

40
Q

Reduction of NADH ketogenesis

A

beta hydoxybutyryl acetoacetate

41
Q

LPP

A

18

42
Q

inc HMG-Coa reductase

A

Insulin

43
Q 
Hydrolyze arachidonic acid from
membrane phospholipids - 
a. epi,
b. thrombin, 
c. bradykinin
d. AOTA
A

AOTA

44
Q

FFA to acyl-coa (enzyme)

A

acyl-coa

synthetase

45
Q

True of chylomicrons except

A

predominantly cholesterol (dapat TAG)

46
Q

Predominant plasma lipid

A

Cholesteryl ester (36%)

47
Q

Most active plasma lipid

A

Unesterified FA

48
Q

Apo A

A

HDL

49
Q

Inhibits PLA from forming eicosanoids:

A

Steroids

50
Q

Oxidation of FA with odd number of Carbon yields?

A

Acetyl CoA + propionyl

51
Q

TRUE/FALSE: Elevated levels of cholesterol in LDL and VLDL is related with atherosclerosis while high HDL levels have a protective effect.

A

True

52
Q

Added to diacylglycerol to form TAG

A

fatty acyl coa?

53
Q

Starting material for ketogenesis:

A

Acetoacetyl CoA

54
Q 
Stimulates the release of arachidonic acid from the membrane phospholipid
A. Epinephrine
B. Thrombin
C. Bradykinin
D. AOTA
A

D. AOTA

55
Q

Cofactor for lipoprotein lipase

A

Apo CII

56
Q

Condensation of 6 IPP requires how many ATP

A

18 ATP

57
Q

Major protein of HDL, activates lecithin: cholesterol acyltransferase, LCAT:

A

Apo A-1

BIOCHEMISTRY (5 decks)

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