Biochemistry Flashcards

1
Q

Us + Es

A

renal function

electrolytes are charged atoms involved in passage of electricity

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2
Q

sodium

A

primary electrolyte in blood
hypo/hyper- natraemia

assess electrolyte, acid-base, water balance, renal function

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3
Q

potassium

A

mostly in cells
hypo/hyper-kalaemia
kidneys, fluid balance, nerve stimulation

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4
Q

IV fluids

A

water cannot be given by itself as it will destroy RBCs

dextrose, saline

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5
Q

urea + creatinine

A

metabolic waste products - nitrogen rich

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6
Q

GFR

A

glomerular filtration rate
= gold standard renal function test

normal > 90
kidney failure < 15

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7
Q

liver function test - enzymes

A

ALT, AST, ALP, GGT

BUT not specific for the liver

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8
Q

bilirubin

A

liver function test
< 21 umol/L
from breakdown of haem
high levels = jaundice

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9
Q

albumin

A
carrying molecule (e.g. Ca)
renal function
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10
Q

plasma proteins used for liver function test

A

total protein + albumin

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11
Q

CRP

A

(c-reactive protein)
marker of inflammation
acute phase protein

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12
Q

transferrin

A

plasma protein

transports iron through blood

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13
Q

fibrinogen

A

plasma protein

coagulation

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14
Q

amylase

A

plasma protein

pancreatic digestive hormone

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15
Q

insulin

A

glucoregulatory hormone

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16
Q

diabetes diagnostic criteria
random G
fasting G
OGTT

A

random > 11.1 mmol/L
fasting > 7.0 mmol/L
OGTT > 11.1

17
Q

normal blood glucose
normal G
OGTT

A

normal < 6.1 mmol/L

OGTT < 7.8 mmol/L

18
Q

hypo
hyper
ketone

A

hypo < 4
hyper > 7
ketone > 15

19
Q

calcium

A

major bone constituent

corrected takes into consideration that calcium is partly bound to proteins in the blood

20
Q

phosphate

A

2nd major constituent of bone

hypo/hyper-phosphateaemia

21
Q

ferritin

A

iron binding protein
represents iron stored in the body

(increased by infection, hepatitis, alcohol, haemochromatosis)

22
Q

urea

A

major excretory product of biochemical metabolism

23
Q

creatinine

A

specialised product of protein breakdown

mark renal function

24
Q

hypertension (lab test)

A

no lab test specifically for

blood pressure

25
Q

blood pressure (mmHg/mmHg)

A

normal: < 130 / < 85
stage 1 HT: 140-159 / 90-99
stage 2 HT: > 160 / > 100

26
Q
suggested lipid profile
Total chol
LDL
HDL
TAGs
A

Total chol: < 4
LDL: < 2
HDL: > 1.2
TAGs: < 1.7