Biochemistry Flashcards
What blood tests can be done to test if the patient is a chronic drinker?
Gamma GT
MCV
Triglycerides
Why are triglycerides high in alcohol excess?
Due to increased synthesis in the liver
If a patient presents to A+E, is unconscious and you suspect they have been drinking what tests should you do?
Glucose - exclude hypoglycaemia
Serum osmolality
What is the simplest formula for serum osmolality?
2x [Na]
What is a normal serum osmolality?
275-295 mmol/kg
A patient comes in comatose and has their electrolytes measured. They come back normal and therefore their calculated osmolality is normal (290 mmol/kg). However their measured osmolality was not (340 mmol/kg). What is this gap called?
Osmolal gap
Something else contributing to osmolality
If an alcoholic has abdominal pain, what should you measure?
Amylase
LFT
What are the liver function tests?
ALT Bilirubin Alk phos Albumin GGT PTR
What is ALT a measure of?
Liver damage
Where is ALT found?
Liver
Where is ALP found?
Liver Bone Small intestine Kidneys Placenta
Where is albumin synthesized?
Liver
Albumin is raised in a systemic inflammatory response. True or false?
False
It false in a systemic inflammatory response
What does the prothrombin ratio measure?
Clotting factors synthesized in the liver
Indicaor of current liver synthetic function
Gives indication of patient’s bleeding tendency
If an alcoholic presents with vomiting, what tests should you do?
U&Es
LFT
Amylase
ABG