Biochemistry

Question 1

What are the subunits of pyruvate dehydrogenase and what is their corresponding prosthetic group?

Answer 1

• E1: TPP
• E2: Lipoamide
• E3: FAD

Question 2

What are the effects of insulin on blood glucose?

Answer 2

• Increase glucose uptake
• Increases glycogen synthesis
• Decreases glycogen breakdown
• Increases glycolysis, acetyl-CoA production
• Increases FA synthesis
• Increases TAG synthesis

Question 3

What are the metabolic effects of epinephrine?

Answer 3

• Increase glycogen breakdown
• Decrease glycogen synthesis
• Increase gluconeogenesis
• Increase glycolysis
• Increase FA mobilization (adipose tissue)
• Increase glucagon secretion
• Decrease insulin secretion

Question 4

What are the metabolic effects of glucagon?

Answer 4

• Increase glycogen breakdown
• Decrease glycogen synthesis
• Decrease glycolysis
• Increase gluconeogenesis
• Increase FA mobilization
• Increase ketogenesis