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INICET > Biochemistry > Flashcards

Biochemistry Flashcards

1
Q

Amanita phalloides inhibits

A

RNA polymerase

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2
Q

Enzymes with ZINC as co factor

A

Carbonic anhydrase
Carboxy peptidase A and B
Cytosolic SOD
Alcohol dehydrogenase
Lactate dehydrogenase
ALA dehydratase
Adenosine deaminase
Alkaline phosphatase

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3
Q

Daily requirement of magnesium

A

400mg/day

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4
Q

At what blood glucose levels, does insulin begin to rise?

A

> 70mg/dL or 3.9mmol/L

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5
Q

Enzymes with magnesium as co factor

A

Kinase
Phosphatase
Mutase
Enolase

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7
Q

Enzyme deficiency in von girkes

A

Glucose 6 phosphatase

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8
Q

Enzyme deficiency in type 1b

A

Transporter of G-6PO4

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9
Q

Enzyme deficiency in Cori’s disease

A

Debranching enzyme

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10
Q

Enzyme deficiency in Anderson’s disease

A

Branching enzyme

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13
Q

Enzyme deficiency in Her’s disease

A

Hepatic Glycogen phosphorylase

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14
Q

Enzyme deficiency in Pompe’s disease

A

Acid maltase

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15
Q

Enzyme deficiency in Mc ardles disease

A

Muscle glycogen phosphorylase

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17
Q

Enzyme deficiency in Tarui’s disease

A

Erythrocyte/ Muscle PFK-1

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18
Q

Michelis menten equation

A

V1= Vmax * [S] / Km + [ S]

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19
Q

Kcat= Vmax/ total enzyme conc

A
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20
Q

Catalytic efficiency of an enzyme=

A

Kcat/Km

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21
Q

Examples of uncompetitive inhibition

A

Phenylalanine inhibits placental ALP

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22
Q

What is an aldonic acid

A

Oxidation at aldehyde group

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23
Q

D and L isomerism

24
Q

What is a uronic acid

A

Oxidation at 6th carbon atom

25
Q

What is a saccharic acid

A

Oxidation at both aldehyde group and 6th C atom

26
Q

Formula for hyaluronic acid

A

N acetyl glucosamine+ glucuronic acid

27
Q

Formula for keratan sulphate

A

N acetyl glucosamine+ galactose

28
Q

Formula for chondroitin sulphate

A

N acetyl galactosamine + glucuronic acid

29
Q

Formula for dermatan sulphate

A

N acetyl galactosamine+ iduronic acid

30
Q

Formula for heparan sulphate

A

Glucosamine + glucuronic acid

31
Q

Formula for heparin

A

Glucosamine+ iduronic acid

32
Q

Common features of mucopolysaccharidosis

A

Gargoylic faces- vertical facies
Frontal bossing
Depressed basal bridge
Gingival hypertrophy
Large tongue
Corneal clouding
Mental retardation
Visceralomegaly
Umbilical hernia

33
Q

Location of glycolysis

34
Q

Location of link reaction

A

Mitochondria

35
Q

Location of glycogenesis

36
Q

What is cahill’s cycle

A

Glucose alanine shuttle

37
Q

What is Cori’s cycle

A

Glucose Lactate shuttle

38
Q

ATP required to form 1 glucose from 2 lactate

40
Q

Enzyme deficiency in classic galactosemia

A

Galactose 1 P uridyl transferase

41
Q

Enzyme deficiency in Hereditary fructose intolerance

A

Aldolase B

42
Q

Specific test for galactosuria

A

Mucic acid test

43
Q

Specific test for fructosuria

A

Seliwanoff test/ Rapid furfural test

44
Q

Phospholipids with nitrogenous base

A

Lecithin
Phosphatidyl serine
Cephalin

45
Q

Phospholipids with non nitrogenous base

A

Cardiolipin
Phosphatidyl inositol
Phosphatidyl glycerol

46
Q

Histology feature in mucopolysaccharidosis

A

Reilly body inclusions in leucocytes

47
Q

Anomerism

48
Q

Epimerism

49
Q

Examples of suicide inhibition

A

Allopurinol inhibits xanthine oxidase
Aspirin inhibits COX
DfMO inhibits ornithine decarboxylase

INICET (17 decks)

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