Biochemistry Flashcards
what is the only amino acid that is achiral?
glycine; it does not have 4 different groups attached the the alpha carbon
what is the only amino acid with an R configuration?
cysteine
are the amino acids found in eukaryotes L or D conformation?
L
will a majority of the species be protonated or deprotonated if the pH is less than the pKa?
protonated
will a majority of the species be protonated or deprotonated if the pH is greater than the pKa?
deprotonated
at very low pH, do amino acids tend to be positively or negatively charged?
positive
what is the pKa of the carboxyl group of an amino acid?
2
what is the pKa of the amino group of an amino acid?
9-10
pKa
pH at which a species is 50% protonated and 50% deprotonated
pH > pKa =
deprotonation
pH < pKa =
protonation
at very high pH, do amino acids tend to be positively or negatively charged?
negative
is the species more likely to be positive or negative at acidic conditions?
positive
is the species more likely to be positive or negative at basic conditions?
negative