Biochemical Engineering Flashcards
The occurrence of cell growth begins with adding a small quantity of living cells to a liquid solution of essential nutrients at a suitable __ and __.
pH, temperature
There are two interacting systems involved – the biological phase consisting of a ___________ and the environmental phase or the _________.
cell population, growth medium
The medium often consists of liquid with dispersed gas bubbles, a liquid-liquid system comprised of immiscible liquid phases, or sometimes a three-phase system with two liquids and one gas phase.
Multiphase
Thermal interaction occurs where cells generate ____, while the medium set the _____ of the cells.
heat, temperature
Commonly, conditions within the biological reactor differ from point to point in space because of the scale of the tank and the high viscosity and non-Newtonian nature of broth in some situations.
Spatial uniformity
On the single-cell level, different cells in the population at a given point in time and
a given small region in space vary with respect to age and chemical activity. Cells of different ages are often characterized by different types of metabolic functions and activities.
Cell-to-cell heterogeneity
- Multicomponent cellular representations
- Single component cellular representations
- A perspective constituting of heterogeneous cells
- A perspective considering average cellular properties
- Structured
- Unstructured
- Segregated
- Unsegregated
Bioreactors which use enzymes to perform biological reactions inside the vessel
Enzyme reactors