Bio344-Exam#3 (Q's & A's) Flashcards
What does the protein cohesin do?
It keeps identical chromosomes attached to each other
What are the components of a proteoglycan?
protein, a tetrasacharide linker and glycosaminoglycans
Which cyclin becomes abundant in a cell when the cell moves from the G2 phase into mitosis?
M cyclin
Which factor below would directly impact filament growth rates?
subunit concentration
What does the protein Myc do?
It is a DNA binding protein that increases transcription of the cyclin D gene which codes for the G1 cyclin.
How does Ca2+ cause muscle contraction?
it binds troponin which shifts tropomyosin on the actin filaments
What happens to microtubules when they lose their GTP cap?
they will likely shrink
What is a function of the basal lamina?
filters toxins from blood in the formation of urine
What is a function of hemidesmosomes?
anchor cells to the extracellular matrix
What would happen in a cell if p27 proteins are degraded?
A p27 protein can bind to a cyclin Cdk complex thus in the absence of p27 many CdK would remain active.
What is the structure of collagen?
Three alpha-helices wrapped around each other
What does the E2F protein do?
It is a DNA binding protein that initiates S-phase gene transcription
What extracellular signal causes a cell to divide?
mitogens
What kind of proteins are gap junctions made out of?
connexins
What happens if the DNA of a dividing cell is damaged?
The enzyme p53 is activated
What could activate the enzyme p53?
DNA damage
What enzyme is responsible for moving a cell between the different phases of the cell cycle?
cyclin dependent kinase
What protein is present in desmosomes?
cadherin
What protein reduces M-CdK levels during the M phase?
APC
How can an active cyclin dependent kinase complex be inactivated?
through inhibitory phosphorylation