BIO106 FINAL EXAM Flashcards
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What’s the difference between large and small animals in terms of energy requirements?
Large animals eat more food, produce more waste. It also takes them longer to mature and reproduce.
Smaller animals lose heat and water more rapidly. They have a higher metabollic rate.
Smaller animals have a larger surface area to volume ratio than larger animals so they lose more heat.
SMALL animals require MORE energy than large animals.
what is homeostasis?
It is the ability to maintain a stable internal enviornement.
what is a homeostatic system? What energy is required?
A homeostatic system are negative feedback loops and composed of a sensor, integrator and effector.
ATP is the form of energy required for the system to function.
what factors must be regulated in biological organisms?
body temperature, pH, blood sugar, blood pressure, response to external stimuli, circadian rythms, allosteric and hormonal regulation of glycolysis, mitochondria regulation,
What is a set point?
The set point of a system is a normal target value for a variable.
What are the 3 components of a homeostatic system?
Sensor, Integrator, Effector
Example: blood sugar regulation
sensor = pancreas (receptors)
integrator = pancreatic beta cells
effector = insulin
BONUS QUESTSTION: what is the name of Dr. Marcec’s cat?
betty
What are the total energy expenditure factors?
How do they relate to homeostasis?
Resting metabollic rate (RMR): referring to body’s basic functions
Non-exercise activity thermogenesis (NEAT): referring to ones daily activities.
Calories burned during exercise
Thermic effect of food (TEF): when we eat
All 4 factors relate to homeostasis because they all represent negative feedback loops that regulate our bodily functions to maintain our internal enviornment.
what are the regulating factors in allosteric regulation of glycolysis & cellular respiration?
Allosteric regulation refers to the activity of an enzyme that’s being modulated by the binding of a regulatory molecule at a site that isn’t the active site on the enzyme.
In terms of glycolysis a high concentration of allosteric inhibitors will stop enzyme activity. High levels of glycolysis products will inhibit the enzymes from continuing to breakdown glucose.
phosphofructokinase is an enzyme that can be inhibited.
This is direct regulation.
what are the regulating factors in hormonal regulation of glycolysis & cellular respiration?
Hormones such as insulin and glucagon are produced by the pancreas and are sensed by cells through receptors on plasma
membrane, activating regulatory pathways.
Insulin promotes glycolysis as it uptakes glucose into cells.
Glucagon promotes glycogenesis in liver so it can release glucose to be a substrate in glycolisis later on
This is indirect regulation.
when is it necessary to use glucogenesis pathway?
The glucogenesis pathway is the opposite of glycolysis. It is used when blood glucose levels are low and the body has to use its reserves within the liver to produce suffiecient glucose within the body.
Usually occurs during starvation or other energy deprived situations.
Why do we get angry when we are hungry?
We get angry when we are hungry because our blood glucose levels drop, causing our bodies to go on alert mode (fight or flight). This paired with adrenaline and cortisol being released makes someone irritable.
What is the importance of body fat?
Body fat is important because:
it provides the most energy and is able to store it for later use
protects us from injury
absorbs vitamins very well
helps maintain our body temperature
synthesizes sterioid hormones
boosts satiety, improves cholestorol levels and helps our immune system
Where do we store our fat?
Body fat is stored within adipose tissue, making up our subcutaneous and visceral fat.
There are 3 type of adipocytes (fat cells)
White fat cells: are the most abundant, 1 fat droplet w/ few organelles. They store energy and insulate the body and cushions vital organs.
Found: underneath skin & internal organs
Beige fat cells: scattered amongst white adipocytes, sometimes generate heat
Found: within white adipose tissue
Brown fat cells: many fat droplets with many mitochondria. Prominent in fetal life and infancy.Generate heat.
Found: upperback & underneath clavicles
What is called when lipid metabolism is out of homeostasis? What are the causes?
It is called obesity.
Can be caused by an unhealthy diet, lack of physical activity, obesity, genetic factors, etc.
what are the advantages and disadvantages of being an ecotherm or endotherm?
Ectotherms: depend on their surroundings to regulate body temp.
Advantages: can hibernate and have low metabollic rates
Disadvantages: limited to only living in certain locations, vulnerable to enviornmental changes
Endotherms: control body temp. regardless of external temp. by generating internal heat.
Advantages: great flexbiility to live anywhere
Disadvantages: high energy requirements, vulnerable to food scarcity
what are the benefits of studying hibernation?
It can help us research transplants, understand aging, life in space, food consumption and therapeutic hypothermia.
Why is oxygen a problem in aerobic organism?
reactive oxygen species are not good, but our cells keep them in check if not it can affect our immune system, if not then we could die from the excess oxygen.
What are the organelles and their functions in the secretory pathway? (There are 5)
- Golgi apparatus: processed and sorted into their final destinations
- Nucleus: Where the DNA comes from, DNA replication and transportation happen here (surrounded by ribosomes
and the ER) - Endoplasmic reticulum (ER): Makes proteins and lipids, making sure proteins are folded correctly.
- Secretory vesicles: transport protein from one place to another inside the cell.
- Plasma membrane: Acts as the cellar broader and releases products outside the cell.
Why are muscles key to animal movement?
Muscles are key to movement because they amplify and coordinate energy expenditures at the molecular level, making possible work at many different levels.
Energy comes from ATP.
What are the functions of muscle tissue?
There are 3 types of muscle tissue (skeletal, cardiac & smooth).
Skeletal muscle pulls on bones, causing movements at the joints.
Smooth muscle supports wall of internal organs
Cardiac muscle in the heart pumps blood.
All protect, generate heat and aide in blood circulation.
What is the structure and function of SMOOTH muscle?
spindle shaped with non-striated unnucleated fibers
involved in involuntary movement.
it is found within walls of internal organs (GI tract, blood vessels, respiratory passages)
What is the structure and function of CARDIAC muscle?
striated & branched; fiborous cells lined with intercalcated discs (gap junctions)
involved in involuntray movements
It is found within the heart as it forms the thick middle layer.
Gap junctions link cardiac muscles so electrical impulses can travel through (ions flowing btwn cells). This starts with the depolarization of Ca2+
*calcium is necessary for muscle movement
What is the structure and function of SKELETAL muscle?
straited cells with myosin and actin fibers organized
they have lots of nuclie and mitochondria
What’s the difference between voluntary and involuntary muscles?
Voluntary muscles are skeletal muscles, as they under conscious control.
Involuntary muscles are smooth and cardiac, they do not work under conscious control.
What are the three muscle energy use classifications?
Type 1 slow oxidative
fibers: small
Contractile speed: slow
Rate of fatgiue: slow
**Type 2A fast oxidative glycolytic **
fibers: medium
contractile speed: fast
rate of fatigue: intermediate
Type 2B fast oxidative glycolytic
fibers: large
contractile speed: fast
rate of fatigue: fast
What is Dr.Marcec’s favorite color?
Blue
What is a sacromere made out of?
What motor proteins are involved?
They are made out of actin and myosin.
myosin heads are braided together to create a thick filament
Actin is attached to z-discs; connects filaments end to end, giving something to pull against. Actin is a thin filament.
What is the use of ATP in muscle movement in terms of kinetic and potential energy?
ATP is used in muscle movement and it works as potential energy and when converted to ADP it is kinetic energy.
atp = pe
adp = ke
Describe vesicle trafficking
- Transported to their specific destination by motor proteins
- Docked by SNARE proteins