Bio week 8 Flashcards
DNA spelled out
deoxyribonucleic acid
DNA definition
a polymer of nucleotides that serves as genetic information
nucleic acid
complex molecules that store and transfer information within a cell; large polymers (complex molecules made of monomers) made of repeating units called nucleotides
uses of nucleic acid
- store information that determines the characteristics of cells and organisms
- direct the synthesis of proteins essential to the operation of the cell or organism
- chemically change (mutate) genetic characteristics that are transmitted to the future generations
- replicate prior to reproduction by directing the manufacturing of copies of itself
- a cell’s ability to make a particular protein comes from the genetic information stored in the cell’s DNA
processes that genetic information controls…
- the digestion and metabolism of nutrients and the elimination of waste
- repair and assembly of cell parts
- reproduction of healthy off spring
- ability to control when and how to react to environmental changes
- coordination and regulation of all life’s essential functions
nucleotide
fundamental subunit of nucleic acid constructed of a:phosphate group. a sugar, an organic nitrogenous base
sugar found in nucleotides
deoxyribose in DNA
ribose in RNA
nitrogenous bases and the base pairing rules
Adenine - Thymine
Cytosine - Guanine
RNA Adenine - Uracil
DNA replication
the process by which a cell makes copies of its DNA
Steps:1. enzyme called “heliacases” attach to DNA and separate the strands forming a “replication bubble”
2. enzyme “DNA Polymerase” helps attach new incoming nucleotides to the exposed strand according to the base pairing rule.
3. in prokaryotic cells, this process starts at one spot: origin of replication. In eukaryotic cells it starts simultaneously in different places
DNA code
the order of the nitrogenous bases is the genetic information to form the proteins. Each sequence of 3 nitrogenous bases is a code word for a single amino acid.proteins are strings of a few to a thousand amino acids.
RNA spelled out
ribonucleic acid
RNA definition
a polymer of nucleotides formed on the template surface of DNA by transcription
3 forms: mRNA, tRNA, rRNA
RNA function
RNA is made in the nucleus by DNA then moves to the cytoplasm to construct (within the ribosome) proteins.
Steps in Protein Synthesis
- Transcription
2. translation
transcription
process of using DNA as a template to synthesize RNA.
RNA polymerase “reads” sequence of DNA nitrogenous bases and uses base pairing rules to build new sequence of RNA
RNA polymerase
enzyme that attaches to DNA moving along strand until locating a “promoter sequence” indicating a “protein coding region” of the strand
coding strand
the part of the separated DNA strand with in the replication bubble used for coding.
termination sequence
nucleotide sequences indicating when RNA polymerase should stop replicating the gene
mRNA
carries the blueprint for making the necessary protein
tRNA
transfers a specific amino acid into the ribosome for assembly into a protein
rRNA
a clover leaf globule of RNA which is part of the ribosome
translation
the process of using the information in RNA to direct protein synthesis by attaching amino acids together
codon
a set of 3 nucleotides that codes for the placement of a specific amino acid
initiation
protein synthesis begins with the small ribosomal subunit binding to the mRNA and moving along until it finds the AUG codon. Then tRNA places MET to the AUG codon on the mRNA and continues placing aminos according to the base pairing rule. This process continues (elongation) until “termination” when the ribosome reaches a stop codon on the mRNA.
nearly universal genetic code
nearly all cells (bacteria, acrchae, plant and animal) use NDA to store genetic information and nearly all use the same codons and same amino acids to form proteins. All eukaryotic cells do this in the nucleus and cytoplasm.