bio vac bac Flashcards

1
Q

Characteristics of a living thing

A

Reproduce, made of cells, use energy, grow/adapt, have a lifespan, respond to their environment

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2
Q

Viruses have what non living, and living characteristics

A

Non living: Are made of biological particles, don’t use energy, don’t grow or have lifespan, don’t respond to environment

Living: Do evolve, reproduce only with a host

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3
Q

Virus structure

A

capsid, nucleic acid, spikes/tail fibres

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4
Q

Viral specificity

A
  • Proteins inside capsid match proteins of cells virus can invade.
  • DNA of virus is more similar to its host than other types of virus.
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5
Q

Name virus with multiple hosts

A

Rabies

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6
Q

Cell structure is different from virus because

A

Virus has capsid, nucleic acid, tail fibres??

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7
Q

what does a virus need to replicate

A

a host cell

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8
Q

Why does lysogenic cycle make you fell sicker than the lytic cycle

A

The lytic cycle attacks quickly whereas the lysogenic cycle will lay dormant for years and not cause an immediate reaction while appearing healthy.

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9
Q

Lytic cycle can be triggered by what

A
  • Traumatic event
  • Compromised immune system
  • Smoking/Poor diet
  • Environmental Chemicals
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10
Q

Three lines of defence

A

First- Physical and chemical barrier
Second- Inflammatory Response
Third- Immune responce

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11
Q

What phagocytes engulf pathogens

A

White blood cells

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12
Q

What is an antigen

A

Made of white blood cells, induce an immune response in the host

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13
Q

Lytic Cycle Steps

A
  1. Attachment and entrance: Virus recognizes host cell and attaches to it. Whole Virus or nucleic acid, enters the cell.
  2. Synthesis of proteins and nucleic acid: Viruses rewire the hosts machinery to replicate its own nucleic acids, enzymes, capsid proteins, and other viral proteins.
  3. Assembly: The viral units assemble into new viral particles
  4. Lysis: Host cell explodes and releases the new viral particles. Can take place in 25-45 minutes.
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14
Q

Lysogenic Cycle Step

A
  • Virus does not kill or cause immediate infection
  • DNA/RNA is replicated along with the host cell DNA
  • coexists with host cell for many cycles while appearing healthy
  • Trigger will activate viral DNA to start lytic cycle such as: traumatic event, compromised immunes system, smoking, environmental chemicals
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15
Q

Symptoms of inflammatory response

A

Swelling, redness, pain in area of infection

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16
Q

Non specific, and specific lines of defence

A

1st, 2nd: Non specific

3rd: Specific

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17
Q

Proteins secreted by lymphocytes

A

Antibodies - attach to pathogens so phagocytic cells can recognize and destroy
Interferons - coat non-infected cells; mask proteins on cell membranes
Interleukins - activate other white blood cells to fight infection

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18
Q

What are vaccines made of

A

Solutions prepared from viral components or inactivated viruses

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19
Q

Vaccines protect us with

A

Passive Immunity - injection of antibodies; short lived ability to fight infection
Active Immunity - live micro organisms that have been cultivated under conditions that disable their virulent properties
Stimulate production of antibodies

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20
Q

Why do scientists want to determine who patient zero is in an epidemic

A

It allows them to learn where the illness originated, and hows it’s transmitted

21
Q

What is a virus with RNA

A

Retrovirus

22
Q

All bacteria are

A

Prokaryotes

23
Q

Bacteria are found under domains

A

Eubacteria (true bacteria)

Archaea (ancient bacteria)

24
Q

Bacteria dates back

A

3.5 billion years

25
Difference between prokaryotes and eukaryotes cells
Prokaryotes: Smaller, No nucleus, genetic material free floating in cytoplasm Eukaryotes: Bigger Nucleus, bound organelles like mitochondria
26
Structure of Bacteria cell
Cell wall: gives bacteria structure Cell membranes: Slows material to pass through Flagellum: Movement Plasmid: Store genetic material/circular Dna
27
3 main shapes of bacteria
Coccus (Sphere) (pnenomia) Bacillus (Rod) (E.coli) Spirillus (Wavy spiral shape) (Siphillis)
28
Autotrophic | Heterotrophic
Autotrophic: Make their own food Heterophobic: obtain food from organic material.
29
Photosynthetic | Chemosynthetic
Autotrophy. Photosynthetic-Bacteria convert CO2 and water to glucose by using energy from sunlight. Chemosynthetic-use energy from chemicals to make glucose
30
Parasitic | Saprophytic
Heterotrophy. Parasitic-Obtain food from living organisms Saprophytic-obtain food from dead organisms also known as decomposers
31
Aerobic Respiration
requires oxygen to obtain energy. Glucose and oxygen converted to water and CO2. (Glucose+O2=H2O+CO2)
32
Anaerobic Respiration (fermentation)
Oxygen is not required. Glucose broken down into alcohol and CO2. (Glucose=Alcohol + CO2 CATP)
33
Obligate aerobes
Must use aerobic respiration
34
Obligate anaerobes
Must use anaerobic respiration. Oxygen is toxic to them.
35
Facultative anaerobes
can switch to anaerobic if needed
36
Antibiotics
Chemicals that inhibit the growth of or destroy bacteria
37
How do antibiotics work
work by targeting properties of bacteria cells that are different form human cells.
38
What is a superbug
Bacteria that has antibiotic resistance which means it can withstand the effect of an antibiotic
39
How can bacteria can become antibiotic resistant
- Natural selection through random mutation. | - Resistance genes are often carried in plasmid and can be passed through conjugation
40
3 Main arrangements of cells
Diplo (pairs) Strepto (chain) Staphylo (clump)
41
Gram + and Gram -
Gram positive: thick peptidoglycan layer that make up cell walls. Appear violet after gram stain. Gram negative: Single thin layer of peptidoglycan layer with outer layer of lipids in its cell walls. Doesn't retain purple dye and turns pink in safranin.
42
how do we identify stained bacteria under microscope
Colour, shape, arrangement
43
why do we grow bacteria on agar
??
44
Each colony represents
a single bacterium that has divided repeatedly
45
Colony morphology is based on
Size, Form, Elevation, Margin, Colour
46
Binary Fission
asexual reproduction. DNA duplicates. Bacteria cell divides producing identical daughter cells
47
Conjugation (horizontal gene transfer)
transfer of DNA between bacteria through cell to cell contact. (sexual reproduction). Plasmid is a small circular piece of DNA is transferred from donor to recipient through piles (hair like appendage)
48
Advantages of binary fission, conjugation
Binary Fission is advantageous because they can reproduce on their own at a much quicker rate. Conjugation requires transfer between 2 bacteria and takes longer. Gene transfer as a faster evolution and is non-random.