Bio Notes Q-Cards Flashcards
what is an immune system?
defense which enables animals to avoid or limit many infections.
what is innate immunity?
a defense that is active immediately upon infection and is the same whether or not the pathogen has been encountered previously
what is adaptive immunity (acquired immune response)?
a defense found only in vertebrates. Animals with adaptive immunity produce a vast arsenal of receptors, each of which recognize a feature typically found only on a particular pathogen
when is adaptive immune response used?
it is activated after the innate immune response and develops more slowly
Innate immunity (rapid response) contains?
Barrier defenses: -skin -mucous membranes -secretions Internal Defenses: - phagocytic cells - natural killer cells - antimicrobial proteins -inflammatory response
adaptive immunity (slower response) contains what?
Humoral Response:
-Antibodies defend against Infection in body fluids
Cell-mediated Response:
-cytotoxic cells defend against infection in body cells
what is a lysozyme?
an enzyme that breaks down bacterial cell walls, further protects the insect digestive system
what is phagocytosis?
cellular ingestion and digestion of bacteria and other foreign substances
Cellular Innate Defenses include what?
- TLR
- Neutrophils
- Macrophages
- Dendritic Cells
- Natural Killer Cells
what are Toll-like Receptors?
bind to fragments of molecules characteristic of a set of pethogens
what are neutrophils?
they circulate in the blood, and are attracted by signals from infected tissues and then engulf and destroy the infecting pathogens
what are macrophages?
“big eaters” , they are large phagocytic cells
some migrate through the body and other reside permanently in organs and tissues where they are likely to encounter pathogens
what are dendritic cells?
mainly populate tissues, such as skin, that contact the environment.
They stimulate adaptive immunity against pathogens they encounter and engulf
what are natural killer cells?
these cells circulate through the body and detect the abnormal array of surface proteins characteristic of some virus-infected and cancerous cells
-they dont engulf, they RELEASE CHEMICALS THAT LEAD TO CELL DEATH
what is the process of innate cell immunity response?
- interstitial fluid in tissues, along with white blood cells in it, enter lymphatic vessels
- fluid inside the lymphatic system flows through lymphatic vessels throughout the body
- within the lymph nodes pathogens and foreign particles in the circulating lymph encounter and activate macrophages and other cells to carry out defense actions
- lymphatic vessels return lymph to the blood via two large ducts that drain into veins near the shoulders
what are internefrons?
proteins that provide innate defense by interfering with viral infections
what is an inflammatory response?
the changes brought about by signaling molecules released upon injury or infection
what is a histamine?
one important inflammatory signaling molecule, which is stored in the granules of mast cells, found in connective tissue
cell adaptive immune response relies on what?
T cells and B Cells, which are types of white blood cells called lymphocytes
where are lymphocytes made?
lymphocytes are made in the bone marrow, but where they mature is what defines what type of cell they will become
lymphocytes that mature in the thymus gland become?
become T cells