Bio: Nervous System Flashcards

1
Q

The nervous system enables organisms to..

A

The NS enables organisms to receive and respond to stimuli from external and internal environments

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2
Q

Neuron

A

Functional unit of the NS.

Converts stimuli into electrochemical signals, which are conducted through NS.

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3
Q

Is the ES or NS faster at responding to stimuli

A

NS

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4
Q

4 kinds of invertebrate NS

A

Protozoa
Cnidaria
Annelida
Arthropoda

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5
Q

Protozoa NS

A

unicellular. no organized NS.

respond to stimuli such as touch, heat, light, chemicals

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6
Q

Cnidaria

A

Nerve net
limited centralization
jellyfish.

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7
Q

annelida

A

Earthworms
Possess a PRIMITIVE CNS with defined ventral nerve cord and anterior “brain” of fused ganglia (nerve cell body clusters)
Nerve pathways from receptors to effectors

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8
Q

arthropoda

A

Arthropod brains are similar to annelid brains.
Arthropods are more specialized sense organs.
compound or simple eyes
tympanum for sounds

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9
Q

Neuron Structure

A

basic building block of NS.

Elongated cell of several dendrites, cell body, single axon.

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10
Q

Dendrite

A

cytoplasmic extensions of the cell body that receive information and transmit it to the cell.

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11
Q

Cell body

A

soma

long cellular process that transmits impulses away from cell body

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12
Q

Myelin

A

Most mammalian axons are sheathed by it.
allows for faster impulses.
Made by glial cells. (oligodendrocytes in CNS
Schwann cells produe yelin in PNS)

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13
Q

Nodes of anvier

A

gasps between myelin

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14
Q

Synaptic terminals

A

axons end. synaptic boutons or knobs

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15
Q

Neurotransmitters are released from?

A

synaptic terminals into synapse clef in gap between axon terminals of one cell and dendrites of next cell

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16
Q

Function of Neuron

A

receive signals from sensory receptors or other neurons.

Transfer this info along axon.

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17
Q

Action potentials

A

Impulses that travel the length of axon and invade nerve terminal, causing NT replease into synapse.

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18
Q

When a neuron is at rest potential difference between extracellular space and intracellular space is

A

Resting potential

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19
Q

Resting potential charge

A

Neuron is polarized here at -70 mV.
inside of neuron is more negative than the outside.
Due to selective ionic permeability of neuronal cell membrane and is maintained by active transport by sodium potassium pump.

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20
Q

Sodium potassium pump

A

Because transmission of action potentials lead to disruption of ionic gradients, the gradients are restored by Na/K pump.
uses ATP transports 3 NA OUT for every 2 K in.
AT REST. pump ensures hi conc of K inside neuron than outside and opposite for Na.

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21
Q

How is the resting potential created?

A

neuron is selectively permeable to K, so K diffuses down its concentration gradient, leaving net negative INSIDE.
Neurons at rest are impermeable to NA so that the cell remains polarized at -70 mV.
Negative proteins are trapped INSIDE cell

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22
Q

Action potential

A

if a cell is sufficiently excited or DEPOLARIZED (inside becomes less negative), then an action potential is gen

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23
Q

Minimum threshold membrane potential

A

-50 mV.

level at which AP is initiated

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24
Q

Ion channels in nerve cell membrane open in response to

A

Changes in voltage.

That’s why theyre called voltage gated ion channels

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25
Q

When does an action potential begin

A

When voltage gated Na channels open in response to small changes inmembrane potential that lead to depolarization thus letting na to rush down its electrochemical gradient, causing a rapid depolarization.
Then the Na channels close, and K channels open, letting K to come in and repolarize to a negative potential

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26
Q

Hyperpolarization

A

Neuron may shoot past the resting potential and become even more negative inside than normal.

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27
Q

Refractory period

A

very difficult or impossible to initiate another action potential… It represents the time Na+ channels need to recover from inactivation.

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28
Q

Describe AP

A

all or none.
nerve fires maximally or not at all.
stimulus intensity is coded by action potential frequency

29
Q

Impulse propagation

A

axons can propagate AP bidirectionally.. but information transfer only goes dendrite to synaptic terminal.

30
Q

Why do synapses operate in one direction?

A

Because refractory periods make the backward travel of AP impossible.

31
Q

The greater the diameter of the axon and the more heavily it is myelinated… the FASTER or SLOWER? the impulses will travel?

A

FASTER.
Myelin increases conduction velocity by insulating axon so that the membrane is permeable to ions only in the nodes of Ranvier.

32
Q

Synapse

A

Gap between axon terminal of one neuron (presynaptic) and the dendrites of another neuron (postsynaptic)

33
Q

How else can neurons communicate?

A

Neurons also may communicate with postsynaptic cells other than neurons, such as cells in muscles or glands called effector cells.

34
Q

What does the nerve terminal contain?

A

neurotransmitters. membrane bound vesicles full of cemical messengers

35
Q

When do the synaptic vesicles fuse with presynaptic membrane?

A

When the AP arrives at the nerve terminal and depolarizes it… the synaptic vesicles fuse with the presynaptic membrane and release NT into the synapse.
NT diffuses across synapse and acts on receptor proteins of the postsynaptic membrane.

36
Q

How do you remove a NT from synapse?

A

Taken back up into the nerve terminal via an uptake carrier protein.It’ll be reused or degraded
It can be degraded by enzymes in synapse (acetylcholinesterase inactivates acetylcholine)
Diffuse out of synapse.

37
Q

Effect of drugs on synapses
Curare
Botulism toxin
Anticholinesterase

A

Curare: block postsynaptic acetylcholine receptors so that acetylcholine cant interact with the receptor… paralysis by blocking nerve impulses to muscles.

Botulism toxin: prevents result of acetylcholine from presynaptic membrane and results in paralysis

Anticholinesterase: used as nerve gases. inhibit acetylcholinesterase. Acetylchoine isn’t degraded in the synapse and continues to affect postsynaptic membrane.no coordinated muscular contractions can happen

38
Q

Afferent neurons

A

Neurons that carry sensory info about EXTERNAL or INTERNAL environment TO BRAIN or SPINAL CORD.

39
Q

Efferent neurons

A

Neurons that carry MOTOR commands FROM BRAIN or SPINAL CORD to various parts of body

40
Q

Interneurons

A

Some neurons only participate in local circuits.
link sensory and motor neurons in brain and spinal cord.
Cell bodies and nerve terminals in same location

41
Q

What is a nerve

A

Bundles of axon covered with connective tissue.

42
Q

What is a cluster of neuronal cell bodies?

A

In the periphery: GANGLIA

In the CNS: NUCLEI

43
Q

NS

A

-Central - brain -spinal cord

Peripheral -somatic -autonomic (-sympathetic -parasympathetic)

44
Q

CNS

A

Brain and spinal cord

45
Q

Brain

A

mass of neurons
outer gray matter (Cell bodies) and inner white matter (myelinated axons)
Forebrain, midbrain, hindbrain

46
Q

Forebrain

T,O,D(t and h)

A

Telencephalon-> cerebral cortex. highly convoluted gray matter that can be seen on the outside of the brain. important for integrating sensory input and motor responses. and vip for memory and creative thought.

Olfactory bulb: center for reception and integration of olfactory

Diencephalon-> has thalamus and hypothalamus
Thalamus->relay and integration center for spinal cord and cerebral cortex
Hypothalamus-> visceral functions… hunger.. thirst.. sex..wter bal..blood p.. temp.. endocrinesystem via feedback

47
Q

Midbrain

A

relay center for visual and auditory impulse

Als in motor control

48
Q

Hindbrain

A

Posterior of brain madeof cerebellum, pons, medulla
CEREBELLUM: modulate motor impulses initiated by cerebral cortex and importance for maintenance of balance, handeye coord. timing of rapid movememnts.
PONS-> relay center to allow cortex to communicate with cerebellum
MEDULLA-> breathing, heart rate, GI

Midbrain. pons. medulla. equals BRAINSTEM

49
Q

Spinal cord

A

Elongated extension of brain that is a conduit for sensory information to brain and motor information from brain

spinal cord can integrate reflexes.

outer is whitematter containing motor and sensory axons. inner graymatter containing nerve cell bodies.

50
Q

Sensory information enters the spinal cord through

A

the dorsal horn

Cell bodies of these sensory neurons are in the dorsal root ganglia

51
Q

all motor information exits the spinal cord through the

A

ventral horn.

reflex, sensory fibers synapse directly on ventral horn motor fibers.

52
Q

PNS

A

nerves and ganglia
sensory nerves which enter CNS and motornerves which leave CNS are part of PNS.
Two primary divisions
SOMATIC. AUTONOMIC NS. both have motor and sensory comp

53
Q

SOMATIC ns

A

innervates skeletal muscles

voluntary move

54
Q

AUTONOMIC ns

A

involuntary ns.
body’s internal enviro without conscious control
ANS innervates cardiac and smooth muscles (blood vess, dig tract, bladder, bronchi)

VIP in bp control, GI motility excretory, resp, rep,

composed of sympathetic andparasympatheic

55
Q

Sympathetic NS

A
fight or flight.
emergency
increases bp, hr, blood flow to skeletal, dilate bronchioles to increasegas exchange.
 decrease gut motility. 
Use norepinenephrine as primary NT
56
Q

Parasympathetic NS

A

conserve enrgy. restore body to rest.
lower hr. increase gut motility.
VAGUS NERVE. uses acetylchoine as a NT to innervate many thoracic and abdominal viscera

57
Q

Eye

A

detects photons and transmits info to brain.

58
Q

eyeball

A

covered by sclera (thick, opaque)
Under sclera is choroid (supplies retina with blood. choroid is dark, pigmented area that reduces reflection in eye)
innermost layer is retina that has photoreceptors that sense light

59
Q

cornea

A

transparent part at front of eye.
bends focuses light rays into pupil, whose diameter is controlled by pigmented, muscley iris.
iris responds to intensity of light. light goes through lens, which is behind pupil.
lens’s shape and focal length are controlled by ciliary muscles. Lens focuses image on to retina

60
Q

What is in retina

A

Photoreceptors. transduce light into AP.
cones hi intensity illumination. contain 3 diff pigments that absorb rgb
Rods low intensity illumination. rod pigment rhodopsin absorbs one wavelength

61
Q

Bipolar cells

A

photoreceptor cells synapse onto bipolar cells which in turn synapse onto ganglion cells. which bundle to form optic nerves which conduct visual info to brain.

62
Q

blind spot

A

point at which optic nerve exits the eye. no photoreceptors.

63
Q

fovea

A

small area of retina packed with cones. vip for high acuity vission

64
Q

eye contains jellylike material called

A

vitreous humor.
helps maintain shape and optical props

aqueous humor is made by eye and exits through ducts to join venous blood.

65
Q

Eye disorders

myopia, hyperopia, astigmatism. cataracts. glaucoma

A

nearsight. farsight. weird cornea shape. opaque lens. increase pressure in eye due to blociking of outflow of aqueous humor.

66
Q

ear

A

transduces sound energy aka pressure waves into impulses perceived by brain as sound

67
Q

sound waves pass through 3 regions as they enter ear

A

outer ear (auricle and auditory canal) to tympanic membrane (eardrum where vibrates at same frequency as incoming sound.) -> 3 ear bones(malleus, incus, and stapes) amplify stimulus and transmit into inner ear (cochlea and vestibular apparatus) for equilibrium.

68
Q

Vibration of ossicles exerts pressure on cochlea fluid, stimulating

A

hair cells in basilar membrane to transduce pressure into AP, which travel via auditory/cochlear nerve to brain for processing.