Bio Explanation- Neural Correlates

Question 1

Neural explanation Sz- dopamine hypothesis

Answer 1

OG Dopamine hypothesis- Hyperdopaminergia in sub cortex causing positive symptoms

Updated dopamine Hypothesis- Davis
Negative- caused by Hypo in mesocortical pathway in the cortex
Positive- caused by Hyper in mesolymbic pathway in Subcortex

Question 2

Neural explanation Sz- Neural differences

Answer 2

Enlarged ventricles fluid filled
Leads to less grey matter and functional neurones
Leads to smaller and lighter (6%) overall brain (brown)

Question 3

Limitation neural explanation Sz (reductionist)

Answer 3

Bio reductionist
Ignores cognitive element

Di forti, etc

Question 4

Limitation neural explanation (correlational)

Answer 4

Correlational
No cause and effect
Treatment fallacy- just giving treatment and decreasing dopamine doesn’t mean dopamine is full cause

Question 5

Strength neural explanation Sz

Answer 5

Supporting evidence
Luckel- avolition negatively correlated with ventral Striation activity (reward centre)
Lower activity= more avolition (in Sz vs control)