Bio Explanation- Genetics

Question 1

Genetic explanation of Sz

Answer 1

Gottesman- found positive correlation between increased genetic similarity of family members and increased risk of developing Sz
Concordance rates- Mz= 48%, Dz= 17% Sibling= 9% parent= 6%

Ripke- candidate gene- genome wide study of 37000 people found 108 candidate gene

Riley and Kendler- life time risk of 1% increases 10x if 1st degree relative has Sz

Aetologically heterogenous

Question 2

Limitation Genetic explanation Sz (reductionist)

Answer 2

Biologically reductionist
Ignores environment
Di forti- smoking THC rich cannabis as teen increases risk of Sz 7x
Mz twins not 100% concordant as expected

Question 3

Strength genetic explanation Sz

Answer 3

Supporting evidence- ripke, gottesman, Riley and Kendal
Brown- risk of child getting Sz increases by over 1.3% if father is over 50

However all correlational

Question 4

Limitation genetic explanation Sz (sensitive)

Answer 4

Socially sensitive research
Blame, worry, anxiety