Bio Explanation 1- Dopamine Flashcards
What is the mesolimbic pathway?
An addictive substance triggers dopamine to be released from the ventral tegmental area (VTA). This leads to feeling pleasure in the nucleus accumbens (Nac).
Jousta et Al (2012) - mesolimbic pathway
Dopamine levels were raised in participants that were given a gambling task regardless of whether the outcome was a win or lose.
Tolerance and withdrawal ( Volkow et Al 1997)
Overtime addictive behaviour causes a decrease in D2 receptors (dopamine) and therefore a decrease in dopamine.
If an addict stops they will experience withdrawal symptoms. Therefore engaging in the activity is more about avoiding withdrawal symptoms than experiencing the initial pleasure.
Maintaining the addiction
When you’ve been taking lots of an addictive substance for a long period of time there is an increased amount of dopamine, this effects the frontal cortex.
What does the frontal cortex do ?(maintaining addiction)
Decision making and memory
Addictive behaviour can change brain circuits.
Can impact the part of the brain the decides what we pay attention to - salience