bio exam 4 Flashcards

1
Q

Darwin’s Heredity Theory

A

Little “Bits” (gemmules) of each trait aggregated in the gamete to form an offspring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The Blending Hypothesis

A

Traits from each parent mixed together and the offspring is a perfect mix of he 2 parents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Gregor Mendel

A

monk
mathematician
pea plants
enginerr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Monohybrid Cross

A

Crossbreeding two organisms in reference to a specific trait

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

True Breeding

A

Only produces 1 of the 2 traits possible over many generations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Mendel established

A

the dominant and recessive relationship between traits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Genotype

A

what gene you are carrying :
AA- Homozygous Dom
Aa- Heterozygous
aa- Homozygous recessive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Phenotype

A

The physical manifestation of the genotype

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Incomplete Dominance

A

The dominant allele determines how much of a gene you have. If mom is white and dad is red, then Aa could show up as pink

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Co-Dominance

A

When two or more dominant alleles are present in one trait Ex: AB blood type

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Pleiotropy

A

One gene at one locus WITH IT’S OWN INDEPENDENT PHENOTYPE, affects the expression of another gene at another locus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Epistasis

A

One gene at one locus WITHOUT IT’S OWN INDEPENDENT PHENOTYPE, affects the expression of another gene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Y chromosome:

A
  • has 75 genes on it
  • All about sexual reproduction and secondary sexual characteristics
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

X chromosome:

A
  • has 1000 genes
  • MOST are about sexual reproduction and secondary sexual characteristics
  • SOME sex linked genes are not about sexual reproduction and secondary sexual characteristics
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Some recessive disorders are sex-linked:

A

Men are more likely to show sex-linked recessive disease because they only have 1 X chromosome and must show whatever that chromosome carries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Carriers must be heterozygous, so what is the only gender that can be a carrier

A

women

17
Q

X-inactivation

A

In the Autosomal/non-sex/somatic cells. one X is randomly activated.

18
Q

Mosaicism

A

Each cell displays traits on only one X

19
Q

Klinefelter’s

A

XXY ( extra X from mom = nondisjunction)

20
Q

Polygenic

A

Many genes affect one characteristic

21
Q

if A = 10% then….

A

T= 10%
C= 40%
G= 40%

22
Q

Origin:

A

Where the enzymes respawn for duplication bind at the chromosome

23
Q

At the origin,

A
  • 2 strands are separated, forming the replication bubble
24
Q

The ends of the replication bubble are called

A

Forks

25
Q

Replication proceeds away from:

A

the origin into the forks in both directions.

26
Q

When 2 bubbles meet they….

A

form together

27
Q

When replication is complete,

A

the 2 daughter DNA mols each consist of an old strand and a new strand

28
Q

What are the 7 enzymes in replication/duplacation

A

Helicase, Topoisomerase, Single stranded binding proteins, Primase, DNA polymerase 3, DNA Polymerase 1, and Ligase

29
Q

Helicase:

A
  • breaks hydrogen bonds
  • unwinds the helix (creates a knot in the DNA)
  • unzips the double strand
30
Q

Topoisomerase

A
  • relieves tension from helicase
  • Cuts off the knot and heals the cut
31
Q

Single Stranded Binding Proteins

A
  • follows helicase and prevents the 2 strands from rezipping
32
Q

Primase

A

initiates replication by building a short RNA primer at the origin

33
Q

DNA polymerase 3

A
  • builds the new complementary DNA strands by adding to the primers
  • Can only build from 5’ to 3’
34
Q

Leading strand

A
  • Runs from 5’ to 3’
  • quick and easy to build
    -runs into the replication fork
35
Q

Lagging strand

A
  • Runs from 3’ to 5’ into rep fork
  • Difficult to build
  • Primase builds multiple primers along the lagging strand
  • DNA poly 3 fills in between the primers in the opposite direction
36
Q

Okazaki Fragments

A

The short segments of DNA between the primers on the lagging strand

37
Q

DNA Polymerase 1

A
  • Removes RNA nucleotides and replaces them with DNA nucleotides
38
Q

Ligase

A
  • Follows DNA poly 1 to check that DNA’s polymerase nucleotides