BIO/BCHM Flashcards

1
Q

these fibers can generate more power (force times velocity) bc thir atpase activity is higher

A

fast twitch

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2
Q

in anaerobic ocnditions, the muscle fiber will undergo _______ resulting in production of ______ and a ______ in cytosolic pH

A

fermentation, lactic acid, decrease ph - will acidify the cytoplasm

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3
Q

in anerobic condiiton, glycogen, with under go fermentation after ____, which will deplte the levels of ____

A

glycolysis, glycogen

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4
Q

in anaroboc condition, what will happen to pyruvate, and it would not interact with the

A

pyruvate go to lactic acid, and not enter the mitochondria for CAC, no ETC in anaerobic

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5
Q

formula for work

A

force X d, product of force applied over a distance an object is moved - look at the power curve (force times velocity), and see when the force is low indicates low work too

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6
Q

for fast twitch fibers they have greater contractile strength - so what woule be a likle property

A

greater calcium pumpin property - movement when calcium binds to troponin, allow for binding of actin and myosin head to produce this contraction

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7
Q

slow twitch fibers have more aerobis so htye have

A

increased capillary density, more mitochondria, high level of oxygen binding proteins

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8
Q

this kind of evoltuion is when unrealted organisms evolve to meet similar envioronmental needs and is associated with analogous structures

A

convergent - features that they INDENPENDANTLY EVOLVE + same enviornment

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9
Q

a bat and butterfly both have wings - what evolution

A

convergent

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10
Q

if animal belong to same species than it cannot be this evolution

A

convergent

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11
Q

in this disease it impact the GnRH produces neurons fail to migrate from the olfactory area to hypothalamus during development - which endocrine axis is affected

A

reproductive

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12
Q

this enzyme prevents the re-coiling of dna strand during replication by addressing the dna strands tendency to supercoiling

A

topoisomerase

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13
Q

this enzyme catalysis separation of parent dna strands at origin of rep

A

helicase

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14
Q

if something lack catalytic activity then it will

A

not active apoptosis

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15
Q

cells undergoing apoptosis will stop their

A

growth (growth arrest), arrest replication of dna, shrink

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16
Q

if cells are not apoptotics then it can become

A

cancerous

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17
Q

an operon contains 2 genes - where are they produced from

A

single mrna transcribed from single promoter in the operon

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18
Q

if the genes share the same operon then means share the

A

same promoter and mrna fragment

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19
Q

with prok - is there alternative splicing

A

NO - transcription and lation happen same time - they have no RNA processing

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20
Q

in the operon it contains a regulatory region which includes the

A

promoter - PART OF OPERON not upstream

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21
Q

a ___inotrope increases the force of _____ and _____ which is mediated by intracell ____levels

A

positive, contraction and contractility, mediated by calcium levels

22
Q

what kind of transport is the Na/K ase

A

primary

23
Q

histone acetyltransferase promote

A

transcription by dec the attractive interaction bw lysine residues in the histones/dna

24
Q

if chromatin is condences then i

A

inhibit transcription

25
Q

when someone frst starts fasting these are actiavted

A

glycogenolysis and gluconeogenesis, maintain blood glucose levels and provide energy

26
Q

during prolonged fasting this helps sustain energy

A

fatty acid oxidation, and ketogenesis, provide sustain energy

27
Q

adrenal medulla is part of which branch of PNS

A

sympathetic branch of ANS only

28
Q

osmotic pressure is porportional to

A

molarity – can do in fractions

29
Q

with hypoxia, lactic fermentation induced to regernate

A

NAD+ –> oxidative phosphorylation is reduced

30
Q

glycogensis occurs depend/indepen to regenerate NAD+

A

independanty

31
Q

if gene is being overexpressed that means it will further amplify it already results

A

so for ex if KO is already low oxygen consumption compare to wildtype, then overexpression of that gene, then it will further lower O2 consumption

32
Q

why is tubulin included

A

is used as contorl to assess the totl protein level - bcs its a cytoskeletal protein whoe expression is similar in different cells - used as loading

33
Q

__ and ___ and ____ often are housekeeping gene and loading control because its constitutively expressed - does not change under hypoxic conditions

A

GAPDH, actin, tubulin

34
Q

if results how compromised or messed tubulin means that the

A

loaded was incorrectly = poor loading

35
Q

palindrome sequenc is when both strands are the same in this dir

A

5” to 3”

36
Q

succinyl coa synthetase produces what

A

succinate, and GTP

37
Q

this gene is parent specifc based on inherited epigenetic modifications

A

imprinted genes (for ex, if off in parent then off in child, and if exlcusive to paternal and affect both sexes)

38
Q

if protein synthesis was under way when the radioative a.a were added, how would the radioativty be distrubuted

A

radioactive a.a. were located only at one end of molecule, only able to incorporate into C terminal of protein - if protein synthesis was underway then for sure N terminues had translated and possinle middle to but since its never done for usre then one end isnt and radio can be there

39
Q

certain viruses contain rna as their genetic material - one of ways these rna viruses replicate themselves is to

A

code for or carry a transcriptase that copies viral rna - reverse

40
Q

only viruses can have ____ as genetic material

A

rna

41
Q

what kind of genetic material does microorganisms have

A

dna

42
Q

rna viruses code for their own ____ that they can use and they do not ____ the hosts own polymerase

A

polymerase, dont alter

43
Q

large amount of protein are found in the urine of pateint - which part of nephorn is malfunctioning

A

glomerulus

44
Q

mucous secretions in the respiratroy tract inhibit microbial infections - these secretions are produces by which of the following tissue types in the lungs

A

epithelial - a specialized goblet cells that produce mucus

45
Q

connective tissue include the

A

blood, fat, bone, cartilage

46
Q

if drug works by blocking the presynaptic neuron reuptake of serotonin then

A

serotonin lasts longer in the synaptic space - spend more time in the synaptic cleft

47
Q

if person has decrease in the SA of the SI leading to dec in nutrient absopriton

A

muscle mass loss - getting body loss

48
Q

in the capillary side , the hydrostatic pressure (water out) is ____ than oncotic

A

greater - goes into the interstitial space/tissues

49
Q

if we increased unabsorbed fats in the body then what happen with osmotic pressure

A

increase the osmotic pressure of intestine - water absorption - causing diarrhea

50
Q

these are osteoblasts that part of bone matrix and involved in cell communication and mechanical sensing

A

osteocytes

51
Q

these break down and reabsorb the matrix

A

osteoclasts

52
Q
A