Bilirubin Pathway Flashcards

1
Q

What diseases are due to a deficiency in UDP gluconyltransferase?

A

Crajer-Najjar and Gilbert’s syndrome

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2
Q

What diseases are due to a deficiency in cMOAT

A

Dubin-Johnson and Rotors Syndrome

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3
Q

What are the carrier molecules of free heam and free Hb

A
Hb = Haptoglobin
Heam = heampexin
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4
Q

What enzyme converts Hb to biliverdin

A

Heam oxygenase

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5
Q

What enzyme converts biliverdin to bilirubin

A

Biliverdin reuctase

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