Bilirubin Pathway Flashcards
1
Q
What diseases are due to a deficiency in UDP gluconyltransferase?
A
Crajer-Najjar and Gilbert’s syndrome
2
Q
What diseases are due to a deficiency in cMOAT
A
Dubin-Johnson and Rotors Syndrome
3
Q
What are the carrier molecules of free heam and free Hb
A
Hb = Haptoglobin Heam = heampexin
4
Q
What enzyme converts Hb to biliverdin
A
Heam oxygenase
5
Q
What enzyme converts biliverdin to bilirubin
A
Biliverdin reuctase