Big Robbins - Female Genital Tract (22)

Question 1

Origin of epithelium and stroma of ovary

Answer 1

Mesodermal Epithelium from wall of yolk sac (Mesonephric, Wolffian ducts)

Question 2

The UG sinus develops when

Answer 2

the cloaca is subdivided by the urorectal septum

Question 3

The UT sinus eventually forms

Answer 3

lower part of vagina and vestibule of external genitalia

Question 4

Gartner Duct Cysts

Answer 4

Rests of residual mesonephric ducts in cervix and vagina

Question 5

The epithelial lining of the female genital tract and the __ share a common origin from coelomic epithelium (mesothelium), which may explain

Answer 5

Ovarian Surface; Morphologically similar lesions arise in various sites w/in female genital tract and adjacent periotoneal surfaces

Question 6

Neisseria gonorrhoeae and Chlamydia are major causes of

Answer 6

Female infertility

Question 7

Candida, Trichomonas, and Gardnerella

Answer 7

May cause significant discomfort, but w/out serious sequelae

Question 8

What develops into Fallopian Tube

Answer 8

Mullerian Duct

Question 9

HSV1 vs HSV2

Answer 9

HSV1 usually oropharyngeal, 2 usually genital mucosa and skin

Question 10

Presentation of HSV infection

Answer 10

Lesions 3-7 days after transmission; Often systemic sx

Question 11

What is this?

Answer 11

Characteristic cytopathic changes in HSV - Intranuclear vira inclusions

Question 12

Having HSV1 before 2 and vice versa

Answer 12

Having HSV1 reduces HSV2 infection; But having HSV2 enhances HSV1 transmission

Question 13

Individuals w/ primary, acute-phase HSV do not have

Answer 13

Anti-HSV serum Ab’s yet

Question 14

Pearly, dome-shaped papules with a dimpled center

Answer 14

Molluscum Contagiosum

Question 15

What is this?

Answer 15

Molluscum: Dome-shaped papule with dimpled center + Intracytoplasmic viral inclusions

Question 16

MCV1 vs 2

Answer 16

MCV1 is most prevalent; MCV2 is most often sexually transmitted

Question 17

Pathogenesis of vaginal Candida infection

Answer 17

DM, Abx, Pregnancy, other conditions yielding compromised neutrophil or Th17 function

Question 18

Dx of Vaginal Candidiasis

Answer 18

Pseudospores or filamentous fungal hyphae in wet KOH mounts of Pap smear

Question 19

Pseudospores or filamentous fungal hyphae on wet KOH mount of Pap smear

Answer 19

Candidiasis

Question 20

Strawberry Cervix

Answer 20

Trichomonas Vaginalis - Mucosa has fiery-red appearance, w/ marked dilation of the cervical mucosal vessels

Question 21

Manifestations of Trichomonas Vaginalis

Answer 21

Strawberry Cervix - Vaginal, Cervical mucosa has fiery red appearance w/ marked dilatation of cervical mucosa vessels

Question 22

Main causes of Bacterial Vaginosis

Answer 22

Gardnerella Vaginalis

Question 23

Presentation of Gardnerella Vaginalis (BV)

Answer 23

Thin, green-gray, fishy vaginal discharge

Question 24

Pap smear in Gardnerella Vaginalis

Answer 24

Superficial and intermediate squamous cells covered with a shaggy coating coccobacilli

Question 25

Superficial and intermediate squamous cells covered with a shaggy coating coccobacilli on Pap Smear

Answer 25

Gardnerella Vaginalis (BV)

Question 26

Gardnerella Vaginalis in pregnancy

Answer 26

Can cause preterm labor

Question 27

Ureaplasma urealyticum and Mycoplasma hominis have been implicated in

Answer 27

Chorioamnionitis and Premature Delivery

Question 28

Chlamydia trachomatis causes

Answer 28

Usually cervicitis, but occasionally ascends to uterus and fallopian tubes

Question 29

Most serious complication of gonorrhea in women

Answer 29

Pelvic Inflammatory Disease

Question 30

2 common causes of Pelvic Inflammatory Disease

Answer 30

Neisseria gon and Chlamydia

Question 31

PID after abortions or deliveries

Answer 31

Usually polymicrobial, including staph, strep, coliforms, and C perf

Question 32

Why do post-surgical PID infections involve deeper layers than gonorrhea infections

Answer 32

Thought to spread upwards via lymphatics or venous channels, rather than on mucosal surfaces

Question 33

What is this?

Answer 33

Acute Salpingitis - Dilated tube lumen and edematous tubal plicae + Pus filling center of fallopian tube

Question 34

What is this?

Answer 34

Chronic Salpingitis - Scarring and fusion of plicae