Beta Adrenergic Antagonists

Question 1

All available beta blockers are ____________ (competetive/noncompetetive) antagonists

Answer 1

Competetive

Question 2

Beta blockers do not induce postural hypotension. Why is that?

Answer 2

Alpha adrenoceptors are functional therefore normal sympathetic control of vasculature is maintained.

Question 3

What are beta blockers used for?

Answer 3

Hypertension
Angina
Cardiac arrhythmias
Myocardial Infarction
Heart failure
Hyperthyroidism
Glaucoma
Migraine headaches

Question 4

Beta adrenoceptor antagonists _________ (increase/decrease) blood pressure, possibly because of their combined effects on heart, RAAS, and CNS.

Answer 4

Decrease

Question 5

Beta blockers have ___________(positive/negative) chronotropic and inotropic effects

Answer 5

Negative

Question 6

How do Beta blockers produce bradycardia?

Answer 6

They depress sinoatrial and atrioventricular nodal activity

Question 7

Beta-1 Blockers are useful in treating angina. Why is that so?

Answer 7

Cardiac output, workload, oxygen consumption is decreased by the blockade of Beta-1 receptors

Question 8

Beta blockers are effective in attenuating _____________ (supraventricular/ventricular) cardiac arrhythmias.

Answer 8

Supraventricular arrhythmias

Question 9

Beta blockers are not effective against ___________ (supraventricular/ventricular) arrhythmias, except those induced by exercise.

Answer 9

Ventricular

Question 10

B1 receptors mediate ______________ (tachycardia/vasodilation)

Answer 10

tachycardia

Question 11

B2 receptors upon stimulation produces _________ (bronchodilation/bronchoconstriction)

Answer 11

bronchodilation

Question 12

B1 receptors are mainly found on the _________ (heart/blood vessels)

Answer 12

heart

Question 13

B2 receptors are mainly found on the _________ (heart/blood vessels)

Answer 13

blood vessels

Question 14

____ (B1/B2) receptors increase myocardial contractility

Answer 14

B1

Question 15

B2 receptor upon stimulation increases ___________ (lipolysis/glycogenolysis)

Answer 15

glycogenolysis (in liver and muscles)

Question 16

B1 receptor upon stimulation increases _________ (lipolysis/glycogenolysis)

Answer 16

lipolysis

Question 17

___ (B1/B2) receptor upon stimulation increases the release of renin

Answer 17

B1

Question 18

B1 receptor mediates effects related to specific organ/tissues. Name them.

Answer 18

Heart (Tachycardia, Increased myocardial contractility)
Adipocytes (Increased lipolysis)
Kidney (Increased renin release)

Question 19

B2 receptors upon stimulation _____________ (increases/decreases) the release of glucagon

Answer 19

Increases

Question 20

B2 receptors upon stimulation produces ___________ (vasoconstriction/vasodilation)

Answer 20

vasodilation

Question 21

B2 receptors upon stimulation ______________ (increases/decreases) peripheral resistance

Answer 21

decreases

Question 22

___ (B1/B2) receptors upon stimulation relaxes uterine smooth muscle

Answer 22

B2

Question 23

Brand name of Acebutolol is ____________

Answer 23

Sectral

Question 24

Brand name of Atenolol is

Answer 24

Tenormin

Question 25

Brand name of Betaxolol is __________

Answer 25

Betoptic-S, Kerlone

Question 26

Brand name of Propanolol is ___________

Answer 26

Inderal LA, Innopran XL

Question 27

Brand name of Nadolol is __________

Answer 27

Corgard

Question 28

Brand name of Timolol is _________

Answer 28

Betimol, Istalol, Timoptic

Question 29

Brand name of Bisoprolol is

Answer 29

Zebeta

Question 30

Brand name of Carteolol is

Answer 30

Cartrol

Question 31

Brand name of Esmolol is __________\\\

Answer 31

Brevibloc

Question 32

Brand name of carvedilol

Answer 32

Coreg

Question 33

Brand name of labetalol is

Answer 33

Trandate

Question 34

Brand name of metoprolol is

Answer 34

Lopressor, Toprol-XL

Question 35

Brand name of nebivolol is

Answer 35

Bystolic

Question 36

Brand name of penbutolol is

Answer 36

Levatol

Question 37

Brand name of pindolol

Answer 37

Visken

Question 38

Brand name of reserpine is

Answer 38

Serpasil

Question 39

Brave Ants Manipulated Everlasting Beautiful Astronauts Nastily. Selective B1 Antagonists

Answer 39

``` Betaxolol Acebutolol Metoprolol Esmolol Bisoprolol Atenolol Nebivolol ```