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Pharmacology - Foundation Module > Beta Adrenergic Antagonists > Flashcards

Beta Adrenergic Antagonists Flashcards

1
Q

All available beta blockers are ____________ (competetive/noncompetetive) antagonists

A

Competetive

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2
Q

Beta blockers do not induce postural hypotension. Why is that?

A

Alpha adrenoceptors are functional therefore normal sympathetic control of vasculature is maintained.

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3
Q

What are beta blockers used for?

A 
Hypertension
Angina
Cardiac arrhythmias
Myocardial Infarction
Heart failure
Hyperthyroidism
Glaucoma
Migraine headaches
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4
Q

Beta adrenoceptor antagonists _________ (increase/decrease) blood pressure, possibly because of their combined effects on heart, RAAS, and CNS.

A

Decrease

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5
Q

Beta blockers have ___________(positive/negative) chronotropic and inotropic effects

A

Negative

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6
Q

How do Beta blockers produce bradycardia?

A

They depress sinoatrial and atrioventricular nodal activity

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7
Q

Beta-1 Blockers are useful in treating angina. Why is that so?

A

Cardiac output, workload, oxygen consumption is decreased by the blockade of Beta-1 receptors

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8
Q

Beta blockers are effective in attenuating _____________ (supraventricular/ventricular) cardiac arrhythmias.

A

Supraventricular arrhythmias

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9
Q

Beta blockers are not effective against ___________ (supraventricular/ventricular) arrhythmias, except those induced by exercise.

A

Ventricular

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10
Q

B1 receptors mediate ______________ (tachycardia/vasodilation)

A

tachycardia

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11
Q

B2 receptors upon stimulation produces _________ (bronchodilation/bronchoconstriction)

A

bronchodilation

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12
Q

B1 receptors are mainly found on the _________ (heart/blood vessels)

A

heart

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13
Q

B2 receptors are mainly found on the _________ (heart/blood vessels)

A

blood vessels

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14
Q

____ (B1/B2) receptors increase myocardial contractility

A

B1

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15
Q

B2 receptor upon stimulation increases ___________ (lipolysis/glycogenolysis)

A

glycogenolysis (in liver and muscles)

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16
Q

B1 receptor upon stimulation increases _________ (lipolysis/glycogenolysis)

A

lipolysis

17
Q

___ (B1/B2) receptor upon stimulation increases the release of renin

A

B1

18
Q

B1 receptor mediates effects related to specific organ/tissues. Name them.

A

Heart (Tachycardia, Increased myocardial contractility)
Adipocytes (Increased lipolysis)
Kidney (Increased renin release)

19
Q

B2 receptors upon stimulation _____________ (increases/decreases) the release of glucagon

A

Increases

20
Q

B2 receptors upon stimulation produces ___________ (vasoconstriction/vasodilation)

A

vasodilation

21
Q

B2 receptors upon stimulation ______________ (increases/decreases) peripheral resistance

A

decreases

22
Q

___ (B1/B2) receptors upon stimulation relaxes uterine smooth muscle

A

B2

23
Q

Brand name of Acebutolol is ____________

A

Sectral

24
Q

Brand name of Atenolol is

A

Tenormin

25
Q

Brand name of Betaxolol is __________

A

Betoptic-S, Kerlone

26
Q

Brand name of Propanolol is ___________

A

Inderal LA, Innopran XL

27
Q

Brand name of Nadolol is __________

A

Corgard

28
Q

Brand name of Timolol is _________

A

Betimol, Istalol, Timoptic

29
Q

Brand name of Bisoprolol is

A

Zebeta

30
Q

Brand name of Carteolol is

A

Cartrol

31
Q

Brand name of Esmolol is __________\\

A

Brevibloc

32
Q

Brand name of carvedilol

A

Coreg

33
Q

Brand name of labetalol is

A

Trandate

34
Q

Brand name of metoprolol is

A

Lopressor, Toprol-XL

35
Q

Brand name of nebivolol is

A

Bystolic

36
Q

Brand name of penbutolol is

A

Levatol

37
Q

Brand name of pindolol

A

Visken

38
Q

Brand name of reserpine is

A

Serpasil

39
Q

Brave Ants Manipulated Everlasting Beautiful Astronauts Nastily. Selective B1 Antagonists

A 
Betaxolol
Acebutolol
Metoprolol
Esmolol
Bisoprolol
Atenolol
Nebivolol

Pharmacology - Foundation Module (3 decks)

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