Benign Tumors and Fibrocystic Changes Flashcards
What is the most common change in the premenopausal breast; thought to be hormone mediated
development of fibrosis and cysts in the breast (fibrocystic change)
Presents as vague irregularity of the breast tissue (‘lumpy breast’), usually in the upper outer quadrant
fibrocystic change
how do benign cysts associated with fibrocystic change appear on gross exam?
blue dome appearance
some fibrocystic changes are associated with an increased risk of invasive carcinoma in
both breasts
fibrocystic changes increase the risk for ductal hyperlasia and sclerosis adenosis
2 fold
fibrocystic changes increase the risk for atypical hyperplasia
5 fold
what do you call papillary growth, usually into a large duct, that is characterized by fibrovascular projections lined by epithelial (luminal) AND myoepithelial cells?
intraductal papilloma
bloody nipple discharge in a premenopausal woman is most likely
intraductal papilloma
bloody nipple discharge differential
intraductal papilloma
papillary carcinoma
histology of papillary carcinoma
fibrovascular projections lined by epithelial cells WITHOUT underlying myoepithelial cells
histology of intraductal papilloma
fibrovascular projections lined by epithelial AND myoepithelial cellls
risk of papillary carcinoma increases with
age, so it’s more common in postmenopausal women
what is the most common benign neoplasm of the breast?
Fibroadenoma
in what population is fibroadenoma usually seen?
premenopausal women
presentation of fibroadenoma
well-circumscribed, mobile, marble-like mass