Bendiak lectures Flashcards
What are the encapsulated lymph organs?
Lymph nodes, thymus, spleen
Where do lymphocytes enter a lymph node from the afferent lymph vessel?
Subcapsular space from the afferent lymph vessel
What are the primary cells of the lymph follicle?
B cells and macrophages
What are the primary cells of the lymph paracortex?
T cells and some B cells
What are the primary cells of the lymph medulla?
B cells, T cells, plasma cells
Where to circulating lymphocytes enter the lymph node?
high endothelial venues
How many lobes does the thymus have?
2
T or F: Mature thymocytes are found mostly in the cortex of the thymus.
False. Found mostly in the medulla of the thymus.
What cells are important for the positive and negative selection and maturation of thymocytes?
Stromal (aka epithelioreticular) cells
T or F: The thymus contains reticular fibers.
FALSE. Lymph nodes have reticular fibers which direct fluid movement through the node.
Where can Hassel?s corpuscles be found?
The thymus.
What do Hassel?s corpuscles do?
Produce thymic stromal lymphoprotein that is important in suppressing autoimmune events.
T or F: The thymus capillaries are leaky and allow for passage of many proteins, cells, and drugs?
False. The thymus has a very selective blood-thymus barrier.
What is the bulk of the lymphoid tissue in the spleen arranged around?
The periarteriolar sheath (PALS)
What is the white pulp of the spleen?
Areas of more organized lymph tissue
