behaviour disorders

Question 1

Psychosis :

Answer 1

loss of reality

Question 2

Schizo-phrenia

Split-brain

Answer 2

associations, affect, ambivalence, autism

Question 3

concordance rate

Answer 3

the likely hood that twins will have a certain disease

Question 4

3 types of Schizo-phrenia

Answer 4

• Simple
• Catatonic (waxy flexibility)
Paranoid

Question 5

Positive symptoms Schizo-phrenia (3)

Answer 5

Hallucinations
• Delusions
• Disorganized, agitated speech

Question 6

The Dopamine Hypothesis Schizo-phrenia

Answer 6

excess DA in forebrain
• Support: DA antagonists e.g. (chlorpromazine) reduce symptoms
• Agonists like l-DOPA bring out symptoms

Question 7

Schizo-phrenia Negative symptoms

Answer 7

• Reduced affect
• Autism
• Waxy flexibility

Question 8

• Disregulation Hypothesis Schizo-phrenia

Answer 8

The involvement of SE

– Clozapine ( Clozaril ) D2 and 5HT2 block

Question 9

Schizo-phrenia 3 methods of treatment

Answer 9

Psychosurgery
• Psychotherapy
• Pharmacotherapy

Question 10

The PCP model

Answer 10

– PCP blocks glutamate (NMDA) receptor
– Glutamate excites GABA
– If no GABA inhibition excess dopamine
– Glutamate’s role in cognition (

Question 11

what can cause negative symptoms

Answer 11

brain damage

Question 12

• Laborit , Charpentier , Delay found that _____ and side effects

Answer 12

Chlorpromazine ( Thorazine ) DA Blocker

extra pyramidal effects, tardive dyskenesia

Question 13

extra pyramidal effects

Answer 13

emors, chorea, dystonia, akinesia, akathisia,

Question 14

tardive dyskenesia

Answer 14

bizzarre facial and tongue movements and a stiff neck, and difficulty swallowing.

Question 15

what are the newer antopsychltics (2)

Answer 15

benzodiazepine, Risperidone (Risperdal)

Question 16

benzodiazepine, Risperidone (Risperdal) blocks_____ and side effects

Answer 16

5HT2  and DA2 blocker

agranulocytosis,anxiety,Gestational disorder

Question 17

learned helplessness

Answer 17

person suffers from a sense of powerlessness, arising from a traumatic event or persistent failure to succeed. It is thought to be one of the underlying causes of depression.

Question 18

bio behavioral effects depression

Answer 18

learned helplessness, nterpersonal stress, frustration punishment,

Question 19

what are the treatment options for depression

Answer 19

ECT most effective electric shock, Antidepressents, trans cranial stimulation

Question 20

tranclpromine (parnate is )

Answer 20

antidpressent MAO Inhibitor

Question 21

eutonil (pagyline)

Answer 21

antidepressent MAO inhibitor

Question 22

phenelezine (Nardil)

Answer 22

antidepressent MAO Inhibitor

Question 23

imipiramine (tofranil)

Answer 23

tricylic antidepressant

Question 24

amitripyline (elavil)

Answer 24

tricylic antidepressant

Question 25

MAO Inhibitor mech. of action, side effects

Answer 25

increases biogernic amnes (DA ,5-HT0, hypertension,fatiuge, agitation

Question 26

tricylic mech. of action, side effects

Answer 26

blocks reuptake of NE,5-HT, Da, apropine side effects ex dry mouth

Question 27

3 main SSRI's

Answer 27

Prozac, (fluoxetine), zoloft (Sertalin), paxil (paroxetine)

Question 28

Prozac, (fluoxetine) can be used for

Answer 28

depression, OCD, anxiety, eating disorders

Question 29

zoloft (Sertalin), is different from prozac

Answer 29

shoter half life

Question 30

paxil (paroxetine)...

Answer 30

most potent and safest SSRi, least side effects (dry mouth, loss of sex drive),

Question 31

what is the difference between mania and hypomania

Answer 31

hyopmania consists of high, optimism ,racing thoughts unrealistic expectations, and the surge of energy Marina is the same as above + irritability and aggression

Question 32

Theory of mania organic brain disorder

Answer 32

Epileptiform activity | Tumors virus and drug, proins

Question 33

Theory of mania biogenic amine hypotheses

Answer 33

Excess of noradrenaline

Question 34

Cade--- invented Litium salts to __________ and what are the behavioral effects of it

Answer 34

Treat mania, effects: sedation ataxia fatigue nausea and slurred speech

Question 35

What is the mechanism of action for lithium salts

Answer 35

Increases every uptake of norepinephrine by 30% inhibits sodium dependent processes and inhibits the enzyme GSK-3

Question 36

How does treat Tegretol mania

Answer 36

Blocks sodium channels ,inhibits enzyme activity

Question 37

How does valproic acid treat mania

Answer 37

Inhibits GABT-T make you behave like a monster (teratological effects)