Behavioral Health

Question 1

lamictal (lamotrigine) SAE

Answer 1

SJS (if drug stopped then suddenly restarted, or if high dose)

Question 2

SIGECAPS

Answer 2

SI, lack of interest, guilt, energy, concentration, appetite, psychomotor agitation, sleep

Question 3

DIGFAST

Answer 3

distractibility, irresponsible, grandiosity, flight of ideas, activity/libido increased, sleep decreased, talkative

Question 4

atypical antidepressant for appetite/sleep

Answer 4

mirtazapine

Question 5

generic version of remeron

Answer 5

mirtazapine

Question 6

serotonin syndrome is what

Answer 6

akathisia, tremor, hyperthermia, HTN, clonus, death

Question 7

NT in migraine

Answer 7

seratonin- too low

Question 8

inhibitory NT

Answer 8

GABA

Question 9

excitatory NTs

Answer 9

glutamate and Ach

Question 10

NT in Alzheimer’s

Answer 10

Ach is underactive

Question 11

histamine originates in the

Answer 11

tuberomamillary nucleus of hypothalamus

Question 12

what to give for muscle contractions d/t atypical antipsychotics

Answer 12

diphendramine IM

Question 13

NT involved in DPN?

Answer 13

seratonin and NE are undersactive

Question 14

NT in anxiety?

Answer 14

GABA and seratonin are underactive

Question 15

NT in Parkinson’s

Answer 15

Ach - overactive, DA - underactive

Question 16

NT in schizophrenia?

Answer 16

DA - hyperactive

Question 17

avoid in pg

Answer 17

fluoxetine, sertraline, amitriptaline

Question 18

fluoxetine, sertraline MOA

Answer 18

blocks SERT

Question 19

duloxetine MOA

Answer 19

blocks SERT + NET

Question 20

rasagline, selegine MOA

Answer 20

inhibit DA degradation by MAO-B

Question 21

carbamazepine MOA

Answer 21

inactiate NA channel to potentiate GABA response

Question 22

benzo MOA

Answer 22

binds to GABA-A site, enhance Cl influx

Question 23

clozapine, olanzapine, risperidone MOA

Answer 23

5HT2 block>D2 block
Facilitate DA release in cortex (less neg sx)
and
D2 antagonis in mesolimibc pathway (less pos sx w/o causing EPS)

Question 24

halperidol

Answer 24

D2 block»5HT2 block

Question 25

antipsychotic w/ high risk of agranulocyosis

Answer 25

clozapine

Question 26

atypical antipsychotic good for elderly (non-sedating)

Answer 26

risperidone (rise and shine)

Question 27

atypical antipsychotic w/ QT prolongation

Answer 27

ziprasidone

Question 28

drug for DPN + migraine

Answer 28

amytriptaline (trycyclic antidepressant)

Question 29

benzo approved as short term sleep aid

Answer 29

triazolam

Question 30

non-SSRI used for GAD that does not cause sedation

Answer 30

buspirone

Question 31

bipolar d/o drugs

Answer 31

lithium, valproic acid, lamoptrigine, olzanapine

Question 32

antidep ok to give kids <14 yo

Answer 32

fluoxetine

Question 33

antidep bad for anxiety b/c if can cause agitation, anxiety, seizure

Answer 33

buproprion - blocks DA uptake, MOA poorly understood

Question 34

cardiac toxicities of TCA

Answer 34

arrthymia, tachycardia, orthostatic HOTN, conduction block

tx w/ LIDOCAINE

Question 35

antiDPN class that can be easiest OD’d on - do not give to pt w/ SI

Answer 35

TCA

Question 36

anticonvulsant w/ high risk of TEN in Han Chinese

Answer 36

carbamezpine

Question 37

other indication of carbamezapine besides anticonvulsant

Answer 37

bipolar d/o, trigeminal neuralgia