Basta 16 Flashcards

1
Q

They can be found in soil, in freshwater and saltwater sediments, and as components of the endogenous microbiota of humans and other animals.

A

ANAEROBIC BACTERIA

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2
Q

anaerobes that exist outside the bodies of animals;
the infections they cause are termed exogenous infections.

A

Exogenous anaerobes

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3
Q

Example of Exogenous anaerobes

A

Genus Clostridium

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4
Q

anaerobes that exist inside the bodies of animals
(endogenous microbiota), the source of endogenous infections.

A

Endogenous anaerobes

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5
Q

Causes Actinomycosis

A

A. Israelii, other Actinomyces spp.

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6
Q

Antibiotic-associated diarrhea. pseudomembranous colitis

A

Clostridium difficile

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7
Q

Bacteremia

A

B. fragilis group, fusobacteria, clostridia, peptostreptococci

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8
Q

Brain abscess

A

Bacteroides spp.,
Prevotella spp.,
Porphyromonas spp.,
Fusobacterium spp.,
Clostridium Spp.

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9
Q

Infections of the female genitourinary tract

A

Peptostreptococci,
Bacteroides spp.,
Clostridium spp.;
Prevotella bivia,
P. disiens,
Actinomyces israelii

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10
Q

Intraabdominal infections, liver abscess, peritonitis, perineal and perirectal infections

A

Bacteroides fragilis group, other
Bacteroides spp., Fusobacterium
spp., C. perfringens, other
Clostridium spp.,
peptostreptococci

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11
Q

Myonecrosis

A

Clostridium perfringens, C. novyi,
C. septicum

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12
Q

Oral, sinus, dental infections

A

Peptostreptococci, Porphyromonas spp., Fusobacterium spp.

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13
Q

Aspiration pneumonia, pleuropulmonary infections

A

Porphyromonas spp., F. nucleatum,
peptostreptococci, B. fragilis
group, Actinomyces spp.

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14
Q

Contamination from the patient’s skin resulting from
poor site preparation during the venipuncture.

A

Propionibacterium acnes

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15
Q

Opportunistic pathogen associated with cases of endocarditis, surgical wounds, and prosthetic joint infections.

A

Propionibacterium acnes

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16
Q

Propionibacterium acnes is isolated from

A

Blood culture

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17
Q

Present in saliva, nasal washings, and gingival and tooth scrapings.

A

Respiratory Tract - Gram-negative anaerobic bacilli (Prevotella, Porphyromonas, and Fusobacterium)

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18
Q

Invasion through the oral mucosa should be suspected whenever oral anaerobes and are recovered from the bloodstream or from abscesses located far from the oral cavity.

A

F. nucleatum and Porphyromonas

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19
Q

In Gastrointestinal Tract, Anaerobes outnumber facultative anaerobes by a factor of

A

1000 :1

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20
Q

accounts for less than 1% of the human intestinal biota

A

Bacteroides fragilisis

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21
Q

most common species of bacteria isolated from human feces.

A

B. vulgatus, B. thetaiotaomicron, and B.
distasonis

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22
Q

What percentage of the bacteria in cervical and vaginal secretions are anaerobes.

A

50%

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23
Q

Anaerobic cocci in Genitourinary Tract

A

Fusobacterium,
Prevotella,
Bacteroides, and
Lactobacillus.

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24
Q

Genitourinary Tract specimens that are unacceptable for anaerobic bacteriology.

A

GU swabs
catheterized urine specimens

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25
Capable of producing spores
Clostridium spp
26
Their toxins usually gain access to the body through ingestion or open wounds that have become contaminated with soil.
Clostridium spp
27
Causes wound or abscess infection, and most can be isolated from the blood in cases of bacteremia.
Clostridium spp
28
Causes food poisoning
Clostridium perfringens
29
Clostridium perfringens is associated with two types of food poisoning
type A (mild and self-limited GI illness) type C (more serious but rarely seen disease)
30
Lacks the ability to produce several essential amino acids (common implication: meats and gravies)
Clostridium perfringens
31
What type of food poisoning caused by C. perfringens enterotoxin linked to sporulation
Type A (8-30 hr incubation period)
32
What type of food poisoning caused by C. perfringens is associated with strains that produce β-toxin and, less commonly, α-toxin (Incubation period of at least 5 to 6 hours)
Type C
33
Causative agent of Botulism
Clostridium botulinum
34
Results from the ingestion of preformed botulinum toxin
Botulism
35
There are seven antigenically different botulinum toxins, only types ________ are associated with human disease.
A, B, and E
36
an extremely potent neurotoxin (attaches to the neuromuscular junction of nerves and prevents the release of acetylcholine ---- flaccid paralysis and death.
Botulinum toxin
37
used to treat strabismus and as a beauty enhancer by temporarily improving frown lines.
Botulinum toxin type A (botox)
38
Causative agent of Tetanus
Clostridium tetani
39
Tetanus is Attributed to the neurotoxin ______ produced by Clostridium tetani.
tetanospasmin
40
acts on inhibitory neurons, preventing the release of neurotransmitters. This results in a spastic type of paralysis, with continuous muscular spasms leading to trismus (lockjaw), risus sardonicus (distorted grin), and difficulty breathing.
Tetanospasmin
41
Tetanus occurs when spores in the environment enter the skin through
puncture wounds.
42
Prevention for Tetanus
diphtheria tetanus-acellular pertussis (DTaP) vaccine
43
Occurs when organisms contaminate wounds, through trauma or surgery.
Myonecrosis or gas gangrene
44
Most common cause of Myonecrosis or gas gangrene
C. perfringens
45
cause necrosis of the tissue and allow deeper penetration by the organisms.
Gas gangrene exotoxins (α-toxin)
46
Clinical manifestations include pain and swelling, bullae (fluid-filled blisters), serous discharge, discoloration, and tissue necrosis.
Myonecrosis or gas gangrene
47
Most common cause of antibiotic-associated diarrhea and pseudomembranous colitis.
Clostridium difficile
48
C. difficile multiply with less competition and produce two toxins:
toxin A (enterotoxin) and toxin B (cytotoxin)
49
Bloody diarrhea with associated necrosis of colonic mucosa
pseudomembranous colitis
50
Chronic, granulomatous, infectious disease characterized by the development of sinus tracts and fistulae, which erupt to the surface and drain pus that may contain so-called sulfur granules.
Actinomycosis
51
Diagnosis: Examinations of wet mounts and Gram-stained preparations of pus from draining sinuses
Actinomycosis
52
can be seen in the maxillary region, but the common site is the female genital tract associated with the use of long-standing intrauterine devices (IUDs)
Actinomycosis
53
the most common cause of actinomycosis
Actinomyces israelii
54
a shift in the vaginal biota occurs, resulting in the overgrowth of other endogenous anaerobes of the vagina
Bacterial Vaginosis
55
Organisms in Bacterial Vaginosis
Mobiluncus spp., Bacteroides spp., Prevotella spp., anaerobic gram-positive cocci, and the aerobic bacterium Gardnerella vaginalis.
56
Clinical features: gray-white, homogenous, malodorous vaginal discharge, with little or no discomfort and no inflammation
Bacterial Vaginosis
57
Associated with an increased risk of a woman acquiring human immunodeficiency virus (HIV) infection, adverse outcomes in pregnancy, and possibly with the pathogenesis of pelvic inflammatory disease.
Bacterial Vaginosis
58
Lactobacilli produce lactic acid from glycogen, which lowers the vaginal pH and suppresses the overgrowth of organisms such as
Mobiluncus, Prevotella, and G. vaginalis.
59
constitutes most of the lactobacilli of the healthy vagina.
Lactobacillus acidophilus complex
60
Opportunistic infections (endocarditis and polymicrobial abscesses) caused by lactobacilli are seen in patients who received the antimicrobial agent
vancomycin.