bassa gnanglia part 1 Flashcards

to learn for final

1
Q

Functions of the basal ganglia

A

-Regulate muscle contraction,force.
-Initiation and termination of movement
-Regulate multi-joint movements .
-control movement sequence.
oculomotor control
-habit learning

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2
Q

what are the motor components of the human basal ganglia :input zone

A

Corpus Striatum which inculdes:

  • Caudate
  • putamen
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3
Q

What do the Striatum (caudate and Putamen) receive and from where?

A

The Caudate and Putamen Receive and process movement-related signals from the cerebral cortex and substantial nigra pars compacta.

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4
Q

Caudate receives input from?

A
  • Multimodal association cortices.

- motor areas in the frontal lobe that control eye movements.

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5
Q

Putamen receives input from?

A
  • S1 and S2 cortices in the parietal lobe.
  • Extrastriate visual cortices in the occipital and temporal lobes.
  • premotor and M1 cortices in the frontal Lobe.
  • Auditory association areas in the temporal lobe.
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6
Q

Neurons and circuits of the basal ganglia :

Main Neurons of the Caudate and the putamen are?

A

the medium spiny neurons

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7
Q

Neurons and circuits of the basal ganglia:

Dendrites of medium spiny neurones receive input from ?

A
  • Cortex
  • Thalamus
  • brainstem
  • other medium spiny neurons
  • local circuit interneurons
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8
Q

Neurons and circuits of the basal ganglia:

Where do Cortical inputs synapse on?

A

on the dendritic spines of the medium spiny neurons

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9
Q

Where do the Dopaminergic inputs come from??

A

the substance nigra pars compacta

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10
Q

Where do the Dopaminergic inputs from the substance nigra pars compacta synapse at?

A

At the base of the dendritic spine,in close proximity to the cortical synapses ,where they selectively modulate cortical input

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11
Q

where the Local circuit neuron and thalamic synapses are made on?

A

on the dendritic shafts and close to the cell soma, where they can modulate the effectiveness of cortical synaptic activation of the more distal end of the dendrites.

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12
Q

Axons from the Medium spiny neurons contact neurons in the ?

A

In the Pallidum (Globus pallidus and substantia nigra pars reticulata)

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13
Q

The palladium includes?

A
  • Globus pallidus

- Substania nigra pars reticulata

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14
Q

The efferent neurons of the globes pallidus and substance nigra pars reticulata influence the?

A

the activity of upper motor neurons located in the motor cortex and the brainstem.

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15
Q

The pathway to the cortex arises primarily in the ?

reaches the motor cortex via?

A

medial division of the globus pallidus, called the internal segment, and reaches the motor cortex via a relay in the ventral anterior and ventral lateral nuclei of the thalamus.

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16
Q

Substania nigra pars reticulata synapse with

A

neurons of superior colliculus that command head and eye movements

17
Q

the main output of the basal ganglia is

A

inhibitory

18
Q

the efferent cells of both the globes pallid us and substantia nigra pars reticulata are

A

GABAergic

19
Q

Substantia nigra pars reticulata project to the thalamus where they relay neurons to the?

A

to the frontal eye fields of premotor cortex

20
Q

what are the role of Basal ganglia

A
  • Basal ganglia are involved in the movement programming
  • Basal ganglia could be involved in the selection and initiation of intended motor programs
  • basal ganglia like rewards to favour certain motor programs.
21
Q

Striatum (Caudate, Putamen)

is output zone or input zone?

A

input zone

22
Q

Palladium (Globus pallidus, Substantia nigra pars reticulata)
is output zone or input zone?

A

output zone