BASOFILOS Y CELULAS CEBADAS (MASTOCITOS) Flashcards

1
Q

Donde se encuentran

A

Basofilos: en el torrente sanguíneo
Células cebadas: en los tejidos

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2
Q

de qué derivan

A

derivan de progenitor célula precursora de GMP (progenitor mieloide granulocitos y monocitos

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3
Q

generación de basófilos

A

interleucina 3 IL-3
linfopoyetina estromal tímica (TSLP)

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4
Q

TIEMPO De vida de los basofilos

A

60 hrs

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5
Q

similitudes basofilos y celulas cebadas

A

comparten mediadores como la histamina, granzyma b, etc

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6
Q

la histamina ß tryptasa viene de

A

el mastocito

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7
Q

funcion de basofilo

A

reacciones alergicas, asma, alergia a alimentos, anafilaxia

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8
Q

granulos

A

proteasas, mediadores lipidecos, citocinas

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9
Q

DONDE ABUNDAN LAS CELULAS CEBADAS

A

en tejidos, mucosas

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10
Q

Estimulo de los basofilos

A

il 3
linfopoyetina estromal tímica TSLP

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11
Q

Caracteristicas

A

granulos basofilos: proteasas, mediadodres lipidicos y citocinas

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12
Q

que mediadores comparten loas basofilos y las celulas cebadas

A
  • Histamina
  • ¡Granzyme B
  • il3
  • IL13
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13
Q

HISTAMINA

A
  • producida por basofilos y celulas cebadas
  • producen alergias, asma y anafilaxia
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14
Q

mecanismo de accion

A

degranulación

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15
Q

basofilia

A

gran cantidad de basofilos

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16
Q

basopenia

A

poca cantidad de basofilos