Basics of Iron Absorption and Function Flashcards
1
Q
Where is non-haem iron mainly found?
A
Cereals
2
Q
Haem iron is mainly derived from?
A
Haemoglobin and myoglobin in red or organ meats
3
Q
Where is iron stored?
A
In macrophages temporarily when Red cells are broken down
4
Q
Where does iiron absorption mainly occur?
A
Duodenum
5
Q
How is haem iron absorbed?
A
Through dedicated haem transporter and non-haem iron is absorbed through DMT-1
6
Q
Major regulator of iron uptake?
A
Hepcidin
-Produced in the liver in response to iron and inflammation
7
Q
Ferroportin facilitates what?
A
Iron export from enterocyte, and it passes the iron onto transferrin for transport elsewhere
8
Q
Assessment of iron status?
A
- Functional iron can be assessed by measuring Hb conc
- Transferrin saturation
- Storage iron by measuring serum ferritin
