BASICS Flashcards

1
Q

First blood transfusion

A

1492- POPE INNOCENT VII

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2
Q

Recommend sodium phosphate as blood preservative

A

Braxton Hicks

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3
Q

Discover the ABO blood group system

A

Karl Landsteiner

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4
Q

Give the ISBT system number of ABO and Rh
First 3: Blood Group System
Last 3: Specific antigen

A

ABO: ISBT 004 001
Rh: ISBT 001 009

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5
Q

Most important of all blood group
Most common cause of HTR and HDN
Associated with IMMEDIATE, INTRAVASCULAR HEMOLYSIS

A

ABO

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6
Q

Specimen: Patient RBC
Known: antisera; anti-A (blue); anti-B (yellow)
Use: Detection of antigens

A

FORWARD TYPING/ front/ direct typing

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7
Q

Universal recipient

A

AB- no antibodies

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8
Q

Other names for reverse typing

A

Back/Indirect/Serum Typing

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9
Q

Specimen: Serum/Plasma
Reagent: A cells, B cells
Use: Detection of antibodies

A

REVERSE TYPING

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10
Q

Universal DONOR of whole blood or packed RBC

A

O- no antigen

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11
Q

Universal DONOR of PLASMA products

A

AB (no antibodies)

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12
Q

Grading Agglutination reactions
A few solid aggregates; mostly free floating cells; supernatant appears red

A

Mixed field

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13
Q

What is the immunodominant sugar of B

A

D-galactose

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14
Q

What is the glycosyltransferase of A

A

N-acetylgalactosyltransferase

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15
Q

What is the immunodominant sugar of A

A

N-acetyl-D-galactosamine

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16
Q

What is the glycosyltransferase of H

A

L-fucosyltransferase

17
Q

Source of anti-A1 lectin

A

Dolichos biflorus

18
Q

Source of anti-B lectin

A

Bandeiraea simplicifiola

19
Q

Genotype of Para-Bombay

A

Hh

20
Q

Weakly reacting or missing antibodies
- most common
- discrepancies on reverse typing

A

GROUP 1

21
Q

Weakly reacting or missing antigens

  • least common
  • discrepancies on forward typing
A

GROUP 2