Basic Structure and Orientation of the eye (tuesday week 2) Flashcards

1
Q

Understand the Basic Structure and Orientation of the eye…

A

Need to know and how to label…
- sclera
- choroid
- retina
- lens
- pupil
- cornea
-RPE
-Cone
-Rod
- Horizontal cell
- bipolar cell
- muller glia
- amacrine cell
- ganglion cell
- optic nerve
- blind spot
- photoreceptor cell
- ciliary muscle
- lens
- iris
- nerve fibers
- optic ganglion?
DORSAL VS VENTRAL SIDE

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2
Q

The octopus retina is “upside down”… What is the advantage?

A
  • inverted retina actually is a superior space-saving solution, especially in small eyes.

The inverted retina has most likely facilitated the evolution of image-forming eyes in vertebrates, and it still benefits especially small and highly visual species.

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3
Q

Compare Octopus retina and human retina (cross sections, histology)

Comapre human vs octopus eye balls

A

draw and label both

slide 4 and slide 5

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4
Q

What retinal ganglion cells are and what they do

A

Retinal ganglion cells (RGCs) are the bridging neurons that connect the retinal input to the visual processing centres within the central nervous system.

Retinal ganglion cells (RGC) bear the sole responsibility of propagating visual stimuli to the brain

Ganglion cells are the projection neurons of the vertebrate retina, conveying information from other retinal neurons to the rest of the brain.

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5
Q

*What photoreceptors are and what they do?

A

Special cells in the eye’s retina that are responsible for converting light into signals that are sent to the brain.

Photoreceptors give us our colour vision and night vision.

Photoreceptor cell -
A photoreceptor cell is a specialized type of neuroepithelial cell found in the retina that is capable of visual phototransduction.

The great biological importance of photoreceptors is that they convert light (visible electromagnetic radiation) into signals that can stimulate biological processes.

There are two types of photoreceptor cells: rods and cones.

The cones are responsible for daytime vision, while the rods respond under dark conditions.

The cones come in three varieties: L, M, and S types (for long, middle, and short wavelength).

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6
Q

what is INNER NUCLEAR LAYER in eye?

A

Inner nuclear layer:
filters out “random noise”

  • found between ganglion cells and photoreceptors
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7
Q

Draw ganglion cells, inner nuclear layer and photoreceptors…

A

slide 6

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8
Q

Which species can read fine print?

Which species can see in the dark?

Human vs octopus

A
  1. Human
  2. octopus
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9
Q

Which species has high acuity?

which species has high sensitivity?

A

slide

  1. species 3: one to one ratio of photoreceptor has partner ganglion cell
  2. species 4 - MASSES of photoreceptors, less ganglion cells - more likely to capture
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10
Q

What does Retinal vasculature looks like in different species…

BLOOD SUPPLY DEVELOPMENT AMPHIBIA

A

BLOOD SUPPLY DEVELOPMENT AMPHIBIA : - ‘Hyaloid (vitreal) vessels stay’

  • ONLY ON FRONT SURFACE (“net stocking”)
  • eg frogs
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11
Q

BLOOD SUPPLY DEVELOPMENT AMPHIBIA : - ‘Hyaloid (vitreal) vessels stay’

look at frog vs tadpole VENTRAL ENTRYB POINT AND DIAGRAM

A
  • Ventral entry point
  • largest blood vessel on surface of retina

SLIDE 8

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12
Q

MAJOR VESSELS AVOID HIGH NERUON DENSITIES (WHEN THEY EXIST)

FAT-TAILED DUNNART

OPPOSSUM OR RAT

RETINAL GANGLION CELLS VS BLOOD VESSELS

A

FAT-TAILED DUNNART -
“Area centralis and visual streak”

OPPOSSUM OR RAT -
“weak or no specialisation”

SLIDE 8- LABEL AND DRAW

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13
Q

Summary of non-mammalian vertebrates: 2

examples of the vertebrates 4

A
  • Everyone has choroid (back)
  • Retinal vessels vary (front)\

examples:
- teleost fish
- amphibians
- reptiles
- birds

(*Concus capillaris not pleated/folded; #pecten is folded)

slide 9

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14
Q

Vertebrates (4) - explain their retinal vessels type and choroid

A
  1. teleost fish - HYALOID VESSELS - Choroid at back
  2. amphibians - HYALOID VESSELS - Choroid at back
  3. reptiles - CONCUS CAPILLARIS - Choroid at back
  4. birds - PECTEN - Choroid at back

(*Concus capillaris not pleated/folded; #pecten is foleded)

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15
Q

What is Fovea?

Why is fovea like a pit?

A

The fovea centralis is a small, central pit composed of closely packed cones in the eye.

It is located in the center of the macula lutea of the retina

The fovea is responsible for sharp central vision (also called foveal vision), which is necessary in humans for activities for which visual detail is of primary importance, such as reading and driving.

The fovea is surrounded by the parafovea belt and the perifovea outer region

The foveal pit is a zone where the inner retinal tissue, including the vasculature, is pushed to one side, leaving a clearer optical zone in the central foveola.

Moreover, inner retinal layers are laterally displaced, resulting in a concave depression called foveal pit

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16
Q

Look at fovea diagrams and the different types

A

slides 11 and 12

17
Q

What is Terrain theory?

A

Terrain theory: how retinal specialisations relate to ecology

Science skeptics are flocking toward a fringe set of beliefs called “terrain theory,” an ideology that ranges from total denial of the existence of viruses and bacteria to the belief that lifestyle choices alone force otherwise benevolent microbes to transform into pathogens

18
Q

LOOK AT DIAGRAM SLIDE 14 AND 15

LABEL SUPERIOR, NASAL, TEMPORAL, INFERIOR OF RETINAL

A

UNDERSTAND

19
Q

What am I and what
happened to me?
(Peichl et al 1992 in unit readings week 1)

A

In response to questions this week: I have looked for retinal
ganglion cell distribution in different dog breeds with little
success.

The most interesting article I found is
https://doi.org/10.1159/000073756

(A Strong Correlation Exists between the Distribution of Retinal Ganglion Cells and Nose Length in the Dog) and I have added it to the week 1 content in unit readings

Unfortunately, the online database of RGC distributions seems to no longer be available, but the original publication is A webbased archive for topographic map

20
Q

Following up on a question in the lecture today: here is an article about the
saccades in the avian retina, you can find it in the Unit Readings for Week 2:
retinal vasculature

A

For more obscure content, consider eye movements in flies:
https://www.sciencedirect.com/science/article/pii/S0960982222018218

I also mentioned retinal energetics a lot: for more information see:
https://doi.org/10.1016/j.brainres.2017.07.025