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ORTHOBULLETS > BASIC SCI > Flashcards

BASIC SCI Flashcards

1
Q

myofibrils activation order

A
  1. type 1 slow oxidative
  2. type 2a intermediate
  3. type 2b fastest most powerful
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2
Q

most powerful myofibil

A

type 2b

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3
Q

osteoblasts activate hematopoietic stem cell pathway via

A

Jagged 1 - Notch pathway

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4
Q

in scoliosis surgery what improves apical translation

A

90 deg rod rotation

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5
Q

collagen fibril size molecule

A

decorin

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6
Q

what is responsbile for tendon crimp

A

elastin

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7
Q

what deposits elastin

A

fibrillin

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8
Q

fxn of Sharpey fibers

A

anchor periosteum to bone/tendon OR ligaments to bone

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9
Q

fxn of calcitonin

A

inhib sclerostin, inhib osteoclast apoptossis causes osteoporosis

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10
Q

fxn of sclerostin

A

inhib bone formation by inhib Wnt pathway

decr osteoblasts

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11
Q

deformation of material by force that acts on it

A

strain

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12
Q

material w different properties based on direction object is loaded

A

anisotropy

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13
Q

force over known area

A

stress

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14
Q

D-zone test used to identify inducible resistance to what abx

A

clindamycin

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15
Q

incr cross linking of UHMWPE

effect on wear or toughness

A

decr both

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16
Q

mechanism of denosumab

A

inhib RANKL

17
Q

how does size and cellularity change in nucleus pulposus proportional to intervertebral disc after birth

A

decr size and cellularity

18
Q

major diff btwn thrombogenesis in ortho vs other surgeries

A

decr antithrombin III

19
Q

wear btwn 2 implant surfaces designed to be in contact

A

adhesion wear

20
Q

wear btwn 2 diff metals not designed to be in contact

A

corrosion

21
Q

abrasive wear when particulates become entrapped and cause wear at articulating surfaces

A

third body wear

22
Q

annealing vs remelting effect on crystal formation of UHMWPE

A 
annealing = incr
remelting = decr crystals
23
Q

sequestrum vs involucrum

A

sequestrum = infected dead bone

involucrum = new bone around infection

24
Q

chondroitin vs keratan sulfate changes w age

A 
decr chondroitin 
incr keratan (replaces chonroitin)
25
Q

type 1 error

A

reject null when it is true

26
Q

type 2 error

A

accept null when it is false

27
Q

blood suppply to scaphoid primarily from

A

dorsal carpal br of radial artery

28
Q

in physeal injury progression of injury across physis starts

A

zone of provisional calcification

then widening of hypertrophic zone

then proliferative zone

29
Q

collagen fiber orientation in superficial vs deep zone

A

superficial = parallel

deep = perpendicular

ORTHOBULLETS (9 decks)

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